General Information of the Cell Line
Cell Line ID
CL000248
Cell Line Name
OCI-AML-2
Synonyms
OCI/AML-2
OCIAML-2
OCI-AML2
OCI/AML2
OCI AML2
OCIAML2
AML-2
Ontario Cancer Institute-Acute Myeloid Leukemia-2
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_1619
Tissue Information
Peripheral blood
Disease
Adult acute myeloid leukemia (NCIt: C9154)
Acute myeloid leukemia with t(6;11)(q27;q23) KMT2A-MLLT4 (NCIt: C132105)
Acute myeloid leukemia (ORDO: Orphanet_519)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT01546, ATP-dependent translocase ABCB1
 Protein Info 
Compound ID Compound Name Compound Formula
CP0036382
 Compound Info 
CAS_52-53-9
   Show/Hide
C27H38N2O4
  1
1
IC50 = 400 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0437846
 Compound Info 
5,7-dimethoxy-2-(3,4,5-trimethoxyphenyl)chromen-4-one
   Show/Hide
C20H20O7
  1
1
IC50 = 400 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0373904
 Compound Info 
5,6,7-trimethoxy-2-(3,4,5-trimethoxyphenyl)chromen-4-one
   Show/Hide
C21H22O8
  1
1
IC50 = 900 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0113396
 Compound Info 
2-(3,4-dimethoxyphenyl)chromen-4-one
   Show/Hide
C17H14O4
  1
1
IC50 = 1200 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0423766
 Compound Info 
2-(3,4-dimethoxyphenyl)-7-methoxychromen-4-one
   Show/Hide
C18H16O5
  1
1
IC50 = 1200 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0486919
 Compound Info 
TRIMETHYLAPIGENIN
   Show/Hide
C18H16O5
  1
1
IC50 = 1400 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0544531
 Compound Info 
2-(3,4-dimethoxyphenyl)-3,6-dimethoxychromen-4-one
   Show/Hide
C19H18O6
  1
1
IC50 = 1900 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0019398
 Compound Info 
3,5,7-trihydroxy-2-(3,4,5-trimethoxyphenyl)chromen-4-one
   Show/Hide
C18H16O8
  1
1
IC50 = 3200 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0335075
 Compound Info 
2-(3,4-dimethoxyphenyl)-5,6,7-trimethoxy-4H-chromen-4-one
   Show/Hide
C20H20O7
  1
1
IC50 = 3200 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0405466
 Compound Info 
2-(3,4-dimethoxyphenyl)-3,7-dihydroxychromen-4-one
   Show/Hide
C17H14O6
  1
1
IC50 = 6300 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0010754
 Compound Info 
2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one
   Show/Hide
C15H10O6
  1
1
IC50 = 19600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0020849
 Compound Info 
2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chromen-4-one
   Show/Hide
C15H10O7
  1
1
IC50 = 52500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Cell Viability or Cytotoxicity Assay
Compound ID Compound Name Compound Formula
CP0002778
 Compound Info 
4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide
   Show/Hide
 C29H31N7O  1
1
GI50 > 10000 nM
   TI
   LI
   LO
   TS
CP0007430
 Compound Info 
IBRUTINIB
   Show/Hide
 C25H24N6O2  1
1
GI50 > 10000 nM
   TI
   LI
   LO
   TS
CP0010193
 Compound Info 
AG-013736
   Show/Hide
 C22H18N4OS  1
1
GI50 = 2360 nM
   TI
   LI
   LO
   TS
CP0035635
 Compound Info 
(2S,5R)-4-[6-(3-Amino-1H-indazol-6-yl)-2-(methylamino)-4-pyrimidinyl]-N-cyclohexyl-5-ethyl-2-morpholinecarboxamide
   Show/Hide
 C25H34N8O2  1
1
IC50 = 890 nM
   TI
   LI
   LO
   TS
CP0035637
 Compound Info 
1,1-Dimethylethyl{(3R,5R)-1-[2-Amino-6-(3-amino-1H-indazol-6-yl)-4-pyrimidinyl]-5-methyl-3-piperidinyl}methylcarbamate
   Show/Hide
 C24H34N8O2  1
1
IC50 = 380 nM
   TI
   LI
   LO
   TS
CP0035650
 Compound Info 
(3S,6R)-1-[6-(3-Amino-1H-indazol-6-yl)-2-(methylamino)-4-pyrimidinyl]-6-methyl-N-phenyl-3-piperidinecarboxamide
   Show/Hide
 C25H28N8O  1
1
IC50 = 580 nM
   TI
   LI
   LO
   TS
CP0204830
 Compound Info 
(2R)-N-[4-[1-[7-(hydroxyamino)-7-oxoheptyl]-4-morpholin-4-ylpyrazolo[3,4-d]pyrimidin-6-yl]phenyl]-2-methylmorpholine-4-carboxamide
   Show/Hide
 C28H38N8O5  1
1
IC50 = 9.01 nM
   TI
   LI
   LO
   TS
CP0383413
 Compound Info 
N-[2-methyl-5-(2-oxo-9-pyrazol-1-ylbenzo[h][1,6]naphthyridin-1-yl)phenyl]prop-2-enamide
   Show/Hide
 C25H19N5O2  1
1
GI50 = 7800 nM
   TI
   LI
   LO
   TS
CP0441015
 Compound Info 
N-[4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-3-[[3-[(E)-2-pyridin-2-ylethenyl]-1H-indazol-6-yl]sulfanyl]propanamide
   Show/Hide
 C30H31F3N6OS  1
1
GI50 = 1420 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Peripheral blood)
Cell Line Name Organism Disease
SET-2
 Cell Line Info 
Homo sapiens (Human) Adult acute megakaryoblastic leukemia
Mono-Mac-6
 Cell Line Info 
Homo sapiens (Human) Adult acute monocytic leukemia
HL-60
 Cell Line Info 
Homo sapiens (Human) Adult acute myeloid leukemia
MOLM-13
 Cell Line Info 
Homo sapiens (Human) Adult acute myeloid leukemia
HL-60/ADR
 Cell Line Info 
Homo sapiens (Human) Adult acute myeloid leukemia
MOLM-14
 Cell Line Info 
Homo sapiens (Human) Adult acute myeloid leukemia
HL60/MDR
 Cell Line Info 
Homo sapiens (Human) Adult acute myeloid leukemia
HL60/MRP
 Cell Line Info 
Homo sapiens (Human) Adult acute myeloid leukemia
NALM-6
 Cell Line Info 
Homo sapiens (Human) Adult B acute lymphoblastic leukemia
MOLT-4
 Cell Line Info 
Homo sapiens (Human) Adult T acute lymphoblastic leukemia
MOLT-4/CCR5
 Cell Line Info 
Homo sapiens (Human) Adult T acute lymphoblastic leukemia
Karpas-299
 Cell Line Info 
Homo sapiens (Human) Anaplastic large cell lymphoma, ALK-positive
M-07e
 Cell Line Info 
Homo sapiens (Human) Childhood acute megakaryoblastic leukemia
THP-1
 Cell Line Info 
Homo sapiens (Human) Childhood acute monocytic leukemia
MV4-11
 Cell Line Info 
Homo sapiens (Human) Childhood acute monocytic leukemia
THP1-Dual
 Cell Line Info 
Homo sapiens (Human) Childhood acute monocytic leukemia
THP1-Dual KO-STING
 Cell Line Info 
Homo sapiens (Human) Childhood acute monocytic leukemia
THP1-Blue ISG
 Cell Line Info 
Homo sapiens (Human) Childhood acute monocytic leukemia
THP1-ASC-GFP
 Cell Line Info 
Homo sapiens (Human) Childhood acute monocytic leukemia
PMNL
 Cell Line Info 
Homo sapiens (Human) Childhood acute monocytic leukemia
THP1-Xblue
 Cell Line Info 
Homo sapiens (Human) Childhood acute monocytic leukemia
SEM
 Cell Line Info 
Homo sapiens (Human) Childhood B acute lymphoblastic leukemia
SEMK2
 Cell Line Info 
Homo sapiens (Human) Childhood B acute lymphoblastic leukemia
Reh
 Cell Line Info 
Homo sapiens (Human) Childhood B acute lymphoblastic leukemia
Jurkat
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
Jurkat E6.1
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
CCRF-CEM
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
CCRF/VCR1000
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
CEM/VLB100
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
CEM/VLB500
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
CEM-SS
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
HPB-ALL
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
CCRF-SB
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
CEM-T4
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
J-Lat 10.6
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
12D7-MDR1
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
MDR CCRF vcr1000
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
FGS7 Jurkat
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
EoL-1
 Cell Line Info 
Homo sapiens (Human) Chronic eosinophilic leukemia, not otherwise specified
CII
 Cell Line Info 
Homo sapiens (Human) Chronic lymphocytic leukemia
Ku812
 Cell Line Info 
Homo sapiens (Human) Chronic myelogenous leukemia, BCR-ABL1 positive
Ri-1
 Cell Line Info 
Homo sapiens (Human) Diffuse large B-cell lymphoma activated B-cell type
Daudi
 Cell Line Info 
Homo sapiens (Human) EBV-related Burkitt lymphoma
HEL
 Cell Line Info 
Homo sapiens (Human) Erythroleukemia
UKE-1
 Cell Line Info 
Homo sapiens (Human) Essential thrombocythemia
L-1236
 Cell Line Info 
Homo sapiens (Human) Hodgkin lymphoma
Granta-519
 Cell Line Info 
Homo sapiens (Human) Mantle cell lymphoma
JeKo-1
 Cell Line Info 
Homo sapiens (Human) Mantle cell lymphoma
Mino
 Cell Line Info 
Homo sapiens (Human) Mantle cell lymphoma
HMC-1
 Cell Line Info 
Homo sapiens (Human) Mast cell leukemia
NK-92
 Cell Line Info 
Homo sapiens (Human) Natural killer cell lymphoblastic leukemia/lymphoma
NK
 Cell Line Info 
Homo sapiens (Human) Natural killer cell lymphoblastic leukemia/lymphoma
KHYG-1
 Cell Line Info 
Homo sapiens (Human) Natural killer cell lymphoblastic leukemia/lymphoma
RPMI-8226
 Cell Line Info 
Homo sapiens (Human) Plasma cell myeloma
OPM-2
 Cell Line Info 
Homo sapiens (Human) Plasma cell myeloma
U266B1
 Cell Line Info 
Homo sapiens (Human) Plasma cell myeloma
KMS-18
 Cell Line Info 
Homo sapiens (Human) Plasma cell myeloma
MM1.S
 Cell Line Info 
Homo sapiens (Human) Plasma cell myeloma
MM1.R
 Cell Line Info 
Homo sapiens (Human) Plasma cell myeloma
OPM-1
 Cell Line Info 
Homo sapiens (Human) Plasma cell myeloma
RPMI-8226/Dox40
 Cell Line Info 
Homo sapiens (Human) Plasma cell myeloma
HuT 78
 Cell Line Info 
Homo sapiens (Human) Sezary syndrome
H9
 Cell Line Info 
Homo sapiens (Human) Sezary syndrome
CREM010i-SS9-1
 Cell Line Info 
Homo sapiens (Human) Sickle cell disease
RBL-1
 Cell Line Info 
Rattus norvegicus (Rat) Rat leukemia
RBL-2H3
 Cell Line Info 
Rattus norvegicus (Rat) Rat leukemia
LCL Orang Asli K28
 Cell Line Info 
Homo sapiens (Human) -
JY
 Cell Line Info 
Homo sapiens (Human) -
C.M.L.
 Cell Line Info 
Homo sapiens (Human) -
BON
 Cell Line Info 
Homo sapiens (Human) -
PBMC iPSC #1
 Cell Line Info 
Homo sapiens (Human) -
LCL 721
 Cell Line Info 
Homo sapiens (Human) -