General Information of the Cell Line
Cell Line ID
CL000596
Cell Line Name
U266B1
Synonyms
U266-B1
U266 B1
U-266
U 266
U266
U266S
U266BL
U266 Bl
266 Bl
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0566
Tissue Information
Peripheral blood
Disease
Plasma cell myeloma (NCIt: C3242)
Multiple myeloma (ORDO: Orphanet_29073)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT01217, Bcl-2-like protein 1
 Protein Info 
Compound ID Compound Name Compound Formula
CP0236848
 Compound Info 
2-(4-fluorophenyl)-5-[[4-[[(2R)-4-[methyl(prop-2-ynyl)amino]-1-phenylsulfanylbutan-2-yl]amino]-3-(trifluoromethylsulfonyl)phenyl]sulfonylcarbamoyl]benzenesulfonyl fluoride
   Show/Hide
C34H30F5N3O7S4
  2
1
EC50 = 590 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
EC50 > 31500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0475606
 Compound Info 
4-(4-fluorophenyl)-N-[4-[[(2R)-4-morpholin-4-yl-1-phenylsulfanylbutan-2-yl]amino]-3-nitrophenyl]sulfonylbenzamide
   Show/Hide
C33H33FN4O6S2
  2
1
EC50 = 2380 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
EC50 > 31500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0096820
 Compound Info 
2-(4-fluorophenyl)-5-[[4-[[(2R)-4-morpholin-4-yl-1-phenylsulfanylbutan-2-yl]amino]-3-nitrophenyl]sulfonylcarbamoyl]benzenesulfonyl fluoride
   Show/Hide
C33H32F2N4O8S3
  2
1
EC50 = 2420 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
EC50 > 31500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0475605
 Compound Info 
2-fluoro-5-[4-[[4-[[(2R)-4-morpholin-4-yl-1-phenylsulfanylbutan-2-yl]amino]-3-nitrophenyl]sulfonylcarbamoyl]phenyl]benzenesulfonyl fluoride
   Show/Hide
C33H32F2N4O8S3
  2
1
EC50 = 4080 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
EC50 > 31500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0475608
 Compound Info 
5-fluoro-2-[4-[[4-[[(2R)-4-morpholin-4-yl-1-phenylsulfanylbutan-2-yl]amino]-3-nitrophenyl]sulfonylcarbamoyl]phenyl]benzenesulfonyl fluoride
   Show/Hide
C33H32F2N4O8S3
  2
1
EC50 = 5630 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
EC50 > 31500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0107763
 Compound Info 
4'-FLUORO-1,1'-BIPHENYL-4-CARBOXYLIC ACID
   Show/Hide
C13H9FO2
  1
1
EC50 > 31500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0236850
 Compound Info 
4-(4-fluorophenyl)-3-fluorosulfonylbenzoic acid
   Show/Hide
C13H8F2O4S
  1
1
EC50 > 31500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0402319
 Compound Info 
2-(4-fluorophenyl)-5-[[4-[[(2R)-4-morpholin-4-yl-1-phenylsulfanylbutan-2-yl]amino]-3-nitrophenyl]sulfonylcarbamoyl]benzenesulfonic acid
   Show/Hide
C33H33FN4O9S3
  1
1
EC50 > 31500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0426659
 Compound Info 
4-(4-fluoro-3-fluorosulfonylphenyl)benzoic acid
   Show/Hide
C13H8F2O4S
  1
1
EC50 > 31500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0434674
 Compound Info 
4-(4-fluoro-2-fluorosulfonylphenyl)benzoic acid
   Show/Hide
C13H8F2O4S
  1
1
EC50 > 31500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0537632
 Compound Info 
4-(4-fluorophenyl)-3-methylsulfonyl-N-[4-[[(2R)-4-morpholin-4-yl-1-phenylsulfanylbutan-2-yl]amino]-3-nitrophenyl]sulfonylbenzamide
   Show/Hide
C34H35FN4O8S3
  1
1
EC50 > 31500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Protein ID: PT02585, Proteasome subunit beta type-5
 Protein Info 
Protein ID: PT01503, Signal transducer and activator of transcription 3
 Protein Info 
Cell Viability or Cytotoxicity Assay
Compound ID Compound Name Compound Formula
CP0006091
 Compound Info 
N-hydroxy-4-[(quinolin-8-ylamino)methyl]benzamide
   Show/Hide
 C17H15N3O2  1
1
GI50 = 40610 nM
   TI
   LI
   LO
   TS
CP0008106
 Compound Info 
N-hydroxy-4-[(quinolin-5-ylamino)methyl]benzamide
   Show/Hide
 C17H15N3O2  1
1
GI50 = 28400 nM
   TI
   LI
   LO
   TS
CP0013049
 Compound Info 
CARFILZOMIB
   Show/Hide
 C40H57N5O7  1
1
IC50 = 35.7 nM
   TI
   LI
   LO
   TS
CP0203135
 Compound Info 
2-[(4-ethoxyphenyl)methyl]-N,1-bis(3-methylbutyl)benzimidazole-5-carboxamide
   Show/Hide
 C27H37N3O2  1
1
IC50 > 40000 nM
   TI
   LI
   LO
   TS
CP0239489
 Compound Info 
4-[4-[[2-(4-chlorophenyl)-4,4-dimethylcyclohexen-1-yl]methyl]piperazin-1-yl]-N-[4-[[6-(hydroxyamino)-6-oxohexyl]amino]-3-nitrophenyl]sulfonyl-2-(1H-pyrrolo[2,3-b]pyridin-5-yloxy)benzamide
   Show/Hide
 C45H51ClN8O8S  1
1
IC50 = 27100 nM
   TI
   LI
   LO
   TS
CP0478334
 Compound Info 
5-chloro-N-[(2S)-4-methyl-1-[[(2S)-4-methyl-1-[[(2R)-4-methyl-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]amino]-1-oxopentan-2-yl]-2-phenylmethoxybenzamide
   Show/Hide
 C32H44ClN3O5  1
1
GI50 = 380 nM
   TI
   LI
   LO
   TS
CP0495584
 Compound Info 
5-chloro-N-[(2S)-4-methyl-1-oxo-1-[[(2S)-1-oxo-3-phenylpropan-2-yl]amino]pentan-2-yl]-2-phenylmethoxybenzamide
   Show/Hide
 C29H31ClN2O4  1
1
GI50 = 14800 nM
   TI
   LI
   LO
   TS
CP0520028
 Compound Info 
5-chloro-N-[(2S)-4-methyl-1-[[(2S)-4-methyl-1-oxo-1-[(1-oxo-3-phenylpropan-2-yl)amino]pentan-2-yl]amino]-1-oxopentan-2-yl]-2-phenylmethoxybenzamide
   Show/Hide
 C35H42ClN3O5  1
1
GI50 = 540 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Peripheral blood)
Cell Line Name Organism Disease
SET-2
 Cell Line Info 
Homo sapiens (Human) Adult acute megakaryoblastic leukemia
Mono-Mac-6
 Cell Line Info 
Homo sapiens (Human) Adult acute monocytic leukemia
HL-60
 Cell Line Info 
Homo sapiens (Human) Adult acute myeloid leukemia
MOLM-13
 Cell Line Info 
Homo sapiens (Human) Adult acute myeloid leukemia
OCI-AML-2
 Cell Line Info 
Homo sapiens (Human) Adult acute myeloid leukemia
HL-60/ADR
 Cell Line Info 
Homo sapiens (Human) Adult acute myeloid leukemia
MOLM-14
 Cell Line Info 
Homo sapiens (Human) Adult acute myeloid leukemia
HL60/MDR
 Cell Line Info 
Homo sapiens (Human) Adult acute myeloid leukemia
HL60/MRP
 Cell Line Info 
Homo sapiens (Human) Adult acute myeloid leukemia
NALM-6
 Cell Line Info 
Homo sapiens (Human) Adult B acute lymphoblastic leukemia
MOLT-4
 Cell Line Info 
Homo sapiens (Human) Adult T acute lymphoblastic leukemia
MOLT-4/CCR5
 Cell Line Info 
Homo sapiens (Human) Adult T acute lymphoblastic leukemia
Karpas-299
 Cell Line Info 
Homo sapiens (Human) Anaplastic large cell lymphoma, ALK-positive
M-07e
 Cell Line Info 
Homo sapiens (Human) Childhood acute megakaryoblastic leukemia
THP-1
 Cell Line Info 
Homo sapiens (Human) Childhood acute monocytic leukemia
MV4-11
 Cell Line Info 
Homo sapiens (Human) Childhood acute monocytic leukemia
THP1-Dual
 Cell Line Info 
Homo sapiens (Human) Childhood acute monocytic leukemia
THP1-Dual KO-STING
 Cell Line Info 
Homo sapiens (Human) Childhood acute monocytic leukemia
THP1-Blue ISG
 Cell Line Info 
Homo sapiens (Human) Childhood acute monocytic leukemia
THP1-ASC-GFP
 Cell Line Info 
Homo sapiens (Human) Childhood acute monocytic leukemia
PMNL
 Cell Line Info 
Homo sapiens (Human) Childhood acute monocytic leukemia
THP1-Xblue
 Cell Line Info 
Homo sapiens (Human) Childhood acute monocytic leukemia
SEM
 Cell Line Info 
Homo sapiens (Human) Childhood B acute lymphoblastic leukemia
SEMK2
 Cell Line Info 
Homo sapiens (Human) Childhood B acute lymphoblastic leukemia
Reh
 Cell Line Info 
Homo sapiens (Human) Childhood B acute lymphoblastic leukemia
Jurkat
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
Jurkat E6.1
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
CCRF-CEM
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
CCRF/VCR1000
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
CEM/VLB100
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
CEM/VLB500
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
CEM-SS
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
HPB-ALL
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
CCRF-SB
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
CEM-T4
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
J-Lat 10.6
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
12D7-MDR1
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
MDR CCRF vcr1000
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
FGS7 Jurkat
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
EoL-1
 Cell Line Info 
Homo sapiens (Human) Chronic eosinophilic leukemia, not otherwise specified
CII
 Cell Line Info 
Homo sapiens (Human) Chronic lymphocytic leukemia
Ku812
 Cell Line Info 
Homo sapiens (Human) Chronic myelogenous leukemia, BCR-ABL1 positive
Ri-1
 Cell Line Info 
Homo sapiens (Human) Diffuse large B-cell lymphoma activated B-cell type
Daudi
 Cell Line Info 
Homo sapiens (Human) EBV-related Burkitt lymphoma
HEL
 Cell Line Info 
Homo sapiens (Human) Erythroleukemia
UKE-1
 Cell Line Info 
Homo sapiens (Human) Essential thrombocythemia
L-1236
 Cell Line Info 
Homo sapiens (Human) Hodgkin lymphoma
Granta-519
 Cell Line Info 
Homo sapiens (Human) Mantle cell lymphoma
JeKo-1
 Cell Line Info 
Homo sapiens (Human) Mantle cell lymphoma
Mino
 Cell Line Info 
Homo sapiens (Human) Mantle cell lymphoma
HMC-1
 Cell Line Info 
Homo sapiens (Human) Mast cell leukemia
NK-92
 Cell Line Info 
Homo sapiens (Human) Natural killer cell lymphoblastic leukemia/lymphoma
NK
 Cell Line Info 
Homo sapiens (Human) Natural killer cell lymphoblastic leukemia/lymphoma
KHYG-1
 Cell Line Info 
Homo sapiens (Human) Natural killer cell lymphoblastic leukemia/lymphoma
RPMI-8226
 Cell Line Info 
Homo sapiens (Human) Plasma cell myeloma
OPM-2
 Cell Line Info 
Homo sapiens (Human) Plasma cell myeloma
KMS-18
 Cell Line Info 
Homo sapiens (Human) Plasma cell myeloma
MM1.S
 Cell Line Info 
Homo sapiens (Human) Plasma cell myeloma
MM1.R
 Cell Line Info 
Homo sapiens (Human) Plasma cell myeloma
OPM-1
 Cell Line Info 
Homo sapiens (Human) Plasma cell myeloma
RPMI-8226/Dox40
 Cell Line Info 
Homo sapiens (Human) Plasma cell myeloma
HuT 78
 Cell Line Info 
Homo sapiens (Human) Sezary syndrome
H9
 Cell Line Info 
Homo sapiens (Human) Sezary syndrome
CREM010i-SS9-1
 Cell Line Info 
Homo sapiens (Human) Sickle cell disease
RBL-1
 Cell Line Info 
Rattus norvegicus (Rat) Rat leukemia
RBL-2H3
 Cell Line Info 
Rattus norvegicus (Rat) Rat leukemia
LCL Orang Asli K28
 Cell Line Info 
Homo sapiens (Human) -
JY
 Cell Line Info 
Homo sapiens (Human) -
C.M.L.
 Cell Line Info 
Homo sapiens (Human) -
BON
 Cell Line Info 
Homo sapiens (Human) -
PBMC iPSC #1
 Cell Line Info 
Homo sapiens (Human) -
LCL 721
 Cell Line Info 
Homo sapiens (Human) -