Cell Line Information

General Information of the Cell Line

Cell Line ID	CL001024
Cell Line Name	MDR CCRF vcr1000
Category	Cancer cell line
Organism	Homo sapiens (Human)
Cellosaurus ID	CVCL_D546
Tissue Information	Peripheral blood
Disease	Childhood T acute lymphoblastic leukemia (NCIt: C7953) Precursor T-cell acute lymphoblastic leukemia (ORDO: Orphanet_99861)

Map of Molecular Bioactivity Related to the Cell Line

Map of Molecular Bioactivity Related to the Cell Line Cell Line Protein Compound Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity

Table of Molecular Bioactivities Related to the Cell Line

Protein ID: PT01546, ATP-dependent translocase ABCB1

Protein Info

Compound ID	Compound Name	Compound Formula
CP0911601 Compound Info	1-[2-[(2R)-3-[4-(2,3-dimethylphenyl)piperazin-1-yl]-2-hydroxypropoxy]phenyl]-3-phenylpropan-1-one Show/Hide	C30H36N2O3	1
1	EC50 = 5.623 nM Bioactivity Info	TI LI LO TS
CP0852429 Compound Info	3-[4-(dimethylamino)phenyl]-1-[2-[(2R)-2-hydroxy-3-[4-(2-methylphenyl)piperazin-1-yl]propoxy]phenyl]propan-1-one Show/Hide	C31H39N3O3	1
1	EC50 = 12.88 nM Bioactivity Info	TI LI LO TS
CP0957074 Compound Info	1-[2-[(2R)-2-hydroxy-3-[4-(2-methylphenyl)piperazin-1-yl]propoxy]phenyl]-3-(4-methoxyphenyl)propan-1-one Show/Hide	C30H36N2O4	1
1	EC50 = 14.13 nM Bioactivity Info	TI LI LO TS
CP0963494 Compound Info	1-[4,5-dichloro-2-[(2R)-2-hydroxy-3-[4-(2-methylphenyl)piperazin-1-yl]propoxy]phenyl]-3-phenylpropan-1-one Show/Hide	C29H32Cl2N2O3	1
1	EC50 = 16.98 nM Bioactivity Info	TI LI LO TS
CP0948701 Compound Info	1-[2-[(2R)-3-[4-(4-fluorophenyl)piperazin-1-yl]-2-hydroxypropoxy]phenyl]-3-naphthalen-1-ylpropan-1-one Show/Hide	C32H33FN2O3	1
1	EC50 = 17.78 nM Bioactivity Info	TI LI LO TS
CP0888659 Compound Info	1-[2-[(2R)-2-hydroxy-3-[4-(2-methylphenyl)piperazin-1-yl]propoxy]phenyl]-3-(4-methylphenyl)propan-1-one Show/Hide	C30H36N2O3	1
1	EC50 = 18.2 nM Bioactivity Info	TI LI LO TS
CP0912168 Compound Info	3-(4-chlorophenyl)-1-[2-[(2R)-2-hydroxy-3-[4-(2-methylphenyl)piperazin-1-yl]propoxy]phenyl]propan-1-one Show/Hide	C29H33ClN2O3	1
1	EC50 = 19.05 nM Bioactivity Info	TI LI LO TS
CP0918348 Compound Info	1-[2-[(2R)-2-hydroxy-3-[4-(2-methylphenyl)piperazin-1-yl]propoxy]-5-methylphenyl]-3-phenylpropan-1-one Show/Hide	C30H36N2O3	1
1	EC50 = 25.7 nM Bioactivity Info	TI LI LO TS
CP0902344 Compound Info	1-[2-[(2R)-2-hydroxy-3-[4-(2-methylphenyl)piperazin-1-yl]propoxy]phenyl]-3-phenylpropan-1-one Show/Hide	C29H34N2O3	1
1	EC50 = 26.92 nM Bioactivity Info	TI LI LO TS
CP0852428 Compound Info	1-[2-[(2R)-2-hydroxy-3-[4-(2-methylphenyl)piperazin-1-yl]propoxy]-4-methoxyphenyl]-3-phenylpropan-1-one Show/Hide	C30H36N2O4	1
1	EC50 = 30.9 nM Bioactivity Info	TI LI LO TS
CP0957076 Compound Info	(2R)-1-[2-[(1S)-1-methoxy-3-phenylpropyl]phenoxy]-3-[4-(2-methylphenyl)piperazin-1-yl]propan-2-ol Show/Hide	C30H38N2O3	1
1	EC50 = 36.31 nM Bioactivity Info	TI LI LO TS
CP0949378 Compound Info	3-(3,4-dichlorophenyl)-1-[2-[(2R)-2-hydroxy-3-[4-(2-methylphenyl)piperazin-1-yl]propoxy]phenyl]propan-1-one Show/Hide	C29H32Cl2N2O3	1
1	EC50 = 38.02 nM Bioactivity Info	TI LI LO TS
CP0942729 Compound Info	3-[4-(dimethylamino)phenyl]-1-[2-[(2R)-2-hydroxy-3-[4-(2-methylphenyl)piperazin-1-yl]propoxy]-4-methoxyphenyl]propan-1-one Show/Hide	C32H41N3O4	1
1	EC50 = 39.81 nM Bioactivity Info	TI LI LO TS
CP0957634 Compound Info	(1S)-1-[2-[(2R)-2-hydroxy-3-[4-(2-methylphenyl)piperazin-1-yl]propoxy]phenyl]-3-phenylpropan-1-ol Show/Hide	C29H36N2O3	1
1	EC50 = 44.67 nM Bioactivity Info	TI LI LO TS
CP0910813 Compound Info	[2-[(2R)-3-[4-[(2S)-3-(2-benzoylphenoxy)-2-hydroxypropyl]piperazin-1-yl]-2-hydroxypropoxy]phenyl]-phenylmethanone Show/Hide	C36H38N2O6	1
1	EC50 = 52.48 nM Bioactivity Info	TI LI LO TS
CP0939950 Compound Info	1-[2-[(2R)-3-[4-(2,3-dimethylphenyl)piperazin-1-yl]-2-hydroxypropoxy]-5-methylphenyl]-3-phenylpropan-1-one Show/Hide	C31H38N2O3	1
1	EC50 = 56.23 nM Bioactivity Info	TI LI LO TS
CP0939939 Compound Info	1-[2-[(2R)-2-hydroxy-3-(4-hydroxy-4-phenylpiperidin-1-yl)propoxy]phenyl]-3-phenylpropan-1-one Show/Hide	C29H33NO4	1
1	EC50 = 57.54 nM Bioactivity Info	TI LI LO TS
CP0870320 Compound Info	1-[5-chloro-2-[(2R)-2-hydroxy-3-[4-(2-methylphenyl)piperazin-1-yl]propoxy]phenyl]-3-phenylpropan-1-one Show/Hide	C29H33ClN2O3	1
1	EC50 = 58.88 nM Bioactivity Info	TI LI LO TS
CP0875953 Compound Info	1-[3-[(2R)-3-[di(propan-2-yl)amino]-2-hydroxypropoxy]phenyl]-3-naphthalen-1-ylpropan-1-one Show/Hide	C28H35NO3	1
1	EC50 = 58.88 nM Bioactivity Info	TI LI LO TS
CP0910805 Compound Info	1-[2-[(2R)-3-[4-(4-fluorophenyl)piperazin-1-yl]-2-hydroxypropoxy]phenyl]-3-phenylpropan-1-one Show/Hide	C28H31FN2O3	1
1	EC50 = 70.79 nM Bioactivity Info	TI LI LO TS
CP0957064 Compound Info	1-[3-[2-hydroxy-3-[4-(2-methylphenyl)piperazin-1-yl]propoxy]phenyl]-3-naphthalen-1-ylpropan-1-one Show/Hide	C33H36N2O3	1
1	EC50 = 70.79 nM Bioactivity Info	TI LI LO TS
CP0957075 Compound Info	1-[3-[(2R)-2-hydroxy-3-[4-(2-methylphenyl)piperazin-1-yl]propoxy]phenyl]-3-phenylpropan-1-one Show/Hide	C29H34N2O3	1
1	EC50 = 74.13 nM Bioactivity Info	TI LI LO TS
CP0911600 Compound Info	1-[2-[(2R)-2-hydroxy-3-(4-hydroxy-4-phenylpiperidin-1-yl)propoxy]phenyl]-3-naphthalen-1-ylpropan-1-one Show/Hide	C33H35NO4	1
1	EC50 = 75.86 nM Bioactivity Info	TI LI LO TS
CP0852434 Compound Info	[2-[(2R)-3-[4-(2,3-dimethylphenyl)piperazin-1-yl]-2-hydroxypropoxy]phenyl]-phenylmethanone Show/Hide	C28H32N2O3	1
1	EC50 = 79.43 nM Bioactivity Info	TI LI LO TS
CP0915090 Compound Info	(2R)-1-(4-benzylpiperazin-1-yl)-3-[2-[(1S)-1-methoxy-3-phenylpropyl]phenoxy]propan-2-ol Show/Hide	C30H38N2O3	1
1	EC50 = 79.43 nM Bioactivity Info	TI LI LO TS
CP0870319 Compound Info	1-[2-[(2R)-3-[di(propan-2-yl)amino]-2-hydroxypropoxy]-5-phenylmethoxyphenyl]-3-phenylpropan-1-one Show/Hide	C31H39NO4	1
1	EC50 = 81.28 nM Bioactivity Info	TI LI LO TS
CP0852432 Compound Info	(1S)-1-[2-[(2R)-3-[4-(2,3-dimethylphenyl)piperazin-1-yl]-2-hydroxypropoxy]phenyl]-3-phenylpropan-1-ol Show/Hide	C30H38N2O3	1
1	EC50 = 83.18 nM Bioactivity Info	TI LI LO TS
CP0963490 Compound Info	1-[2-[(2R)-2-hydroxy-3-(4-hydroxy-4-phenylpiperidin-1-yl)propoxy]-5-phenylmethoxyphenyl]-3-phenylpropan-1-one Show/Hide	C36H39NO5	1
1	EC50 = 85.11 nM Bioactivity Info	TI LI LO TS
CP0380591 Compound Info	N-[2-[(3-acetyl-2,4,6-trimethylphenyl)methylsulfanyl]-1,3-benzothiazol-6-yl]-4-butoxybenzamide Show/Hide	C30H32N2O3S2	1
1	EC50 = 97.72 nM Bioactivity Info	TI LI LO TS
CP0875948 Compound Info	1-[2-[(2R)-2-hydroxy-3-(propylamino)propoxy]-5-phenylmethoxyphenyl]-3-phenylpropan-1-one Show/Hide	C28H33NO4	1
1	EC50 = 109.65 nM Bioactivity Info	TI LI LO TS
CP0939940 Compound Info	1-[2-[(2R)-3-(4-benzylpiperazin-1-yl)-2-hydroxypropoxy]-5-phenylmethoxyphenyl]-3-phenylpropan-1-one Show/Hide	C36H40N2O4	1
1	EC50 = 114.82 nM Bioactivity Info	TI LI LO TS
CP0942727 Compound Info	1-[4-[(2R)-3-[di(propan-2-yl)amino]-2-hydroxypropoxy]phenyl]-3-naphthalen-1-ylpropan-1-one Show/Hide	C28H35NO3	1
1	EC50 = 114.82 nM Bioactivity Info	TI LI LO TS
CP0902356 Compound Info	1-[2-[(2R)-3-(3,3-diphenylpropylamino)-2-hydroxypropoxy]phenyl]propan-1-one Show/Hide	C27H31NO3	1
1	EC50 = 120.23 nM Bioactivity Info	TI LI LO TS
CP0948699 Compound Info	1-[4,5-dichloro-2-[(2R)-2-hydroxy-3-[4-(2-methylphenyl)piperazin-1-yl]propoxy]phenyl]ethanone Show/Hide	C22H26Cl2N2O3	1
1	EC50 = 125.89 nM Bioactivity Info	TI LI LO TS
CP0949379 Compound Info	1-[2-[(2R)-3-(4-benzoylpiperazin-1-yl)-2-hydroxypropoxy]phenyl]-3-phenylpropan-1-one Show/Hide	C29H32N2O4	1
1	EC50 = 128.82 nM Bioactivity Info	TI LI LO TS
CP0377383 Compound Info	3-phenyl-1-(2-(8-(piperidin-1-yl)octyloxy)phenyl)propan-1-one Show/Hide	C28H39NO2	1
1	EC50 = 138.04 nM Bioactivity Info	TI LI LO TS
CP0933743 Compound Info	1-[3-[(2R)-3-[4-(2,3-dimethylphenyl)piperazin-1-yl]-2-hydroxypropoxy]phenyl]-3-phenylpropan-1-one Show/Hide	C30H36N2O3	1
1	EC50 = 138.04 nM Bioactivity Info	TI LI LO TS
CP0902354 Compound Info	(2R)-2-benzyl-4-[(2R)-2-hydroxy-3-piperidin-1-ylpropoxy]-2,3-dihydroinden-1-one Show/Hide	C24H29NO3	1
1	EC50 = 141.25 nM Bioactivity Info	TI LI LO TS
CP0869421 Compound Info	1-[3-[(2R)-2-hydroxy-3-piperidin-1-ylpropoxy]phenyl]-3-naphthalen-1-ylpropan-1-one Show/Hide	C27H31NO3	1
1	EC50 = 144.54 nM Bioactivity Info	TI LI LO TS
CP0939942 Compound Info	1-[2-[(2R)-3-[[(R)-cyclohexyl(phenyl)methyl]amino]-2-hydroxypropoxy]phenyl]-3-phenylpropan-1-one Show/Hide	C31H37NO3	1
1	EC50 = 144.54 nM Bioactivity Info	TI LI LO TS
CP0957072 Compound Info	[2-[(2R)-3-[4-(4-fluorophenyl)piperazin-1-yl]-2-hydroxypropoxy]phenyl]-phenylmethanone Show/Hide	C26H27FN2O3	1
1	EC50 = 147.91 nM Bioactivity Info	TI LI LO TS
CP0910803 Compound Info	1-[3-[3-[4-(4-fluorophenyl)piperazin-1-yl]-2-hydroxypropoxy]phenyl]-3-naphthalen-1-ylpropan-1-one Show/Hide	C32H33FN2O3	1
1	EC50 = 158.49 nM Bioactivity Info	TI LI LO TS
CP0852430 Compound Info	1-[2-[(2R)-2-hydroxy-3-[4-(2-methylphenyl)piperazin-1-yl]propoxy]-4-methylphenyl]ethanone Show/Hide	C23H30N2O3	1
1	EC50 = 162.18 nM Bioactivity Info	TI LI LO TS
CP0939943 Compound Info	(2S)-2-benzyl-7-[(2R)-3-[4-(2,3-dimethylphenyl)piperazin-1-yl]-2-hydroxypropoxy]-2,3-dihydroinden-1-one Show/Hide	C31H36N2O3	1
1	EC50 = 165.96 nM Bioactivity Info	TI LI LO TS
CP0947507 Compound Info	1-[2-[(2R)-2-hydroxy-3-[4-(2-methylphenyl)piperazin-1-yl]propoxy]phenyl]propan-1-one Show/Hide	C23H30N2O3	1
1	EC50 = 169.82 nM Bioactivity Info	TI LI LO TS
CP0856350 Compound Info	1-[2-[(2R)-2-hydroxy-3-piperidin-1-ylpropoxy]phenyl]-3-naphthalen-1-ylpropan-1-one Show/Hide	C27H31NO3	1
1	EC50 = 173.78 nM Bioactivity Info	TI LI LO TS
CP0913301 Compound Info	1-[2-[(2R)-2-hydroxy-3-piperidin-1-ylpropoxy]-5-phenylmethoxyphenyl]-3-phenylpropan-1-one Show/Hide	C30H35NO4	1
1	EC50 = 173.78 nM Bioactivity Info	TI LI LO TS
CP0939952 Compound Info	[3-[(2R)-3-[4-(2,3-dimethylphenyl)piperazin-1-yl]-2-hydroxypropoxy]phenyl]-phenylmethanone Show/Hide	C28H32N2O3	1
1	EC50 = 173.78 nM Bioactivity Info	TI LI LO TS
CP0942742 Compound Info	(2R)-1-[2-[(1R)-1-methoxy-3-phenylpropyl]phenoxy]-3-piperidin-1-ylpropan-2-ol Show/Hide	C24H33NO3	1
1	EC50 = 173.78 nM Bioactivity Info	TI LI LO TS
CP0489792 Compound Info	3-phenyl-1-(2-(7-(piperidin-1-yl)heptyloxy)phenyl)propan-1-one Show/Hide	C27H37NO2	1
1	EC50 = 177.83 nM Bioactivity Info	TI LI LO TS
CP0902355 Compound Info	1-[4-[(2R)-3-(3,3-diphenylpropylamino)-2-hydroxypropoxy]phenyl]ethanone Show/Hide	C26H29NO3	1
1	EC50 = 177.83 nM Bioactivity Info	TI LI LO TS
CP0905119 Compound Info	1-[2-[(2R)-2-hydroxy-3-[4-(2-methylphenyl)piperazin-1-yl]propoxy]-5-methoxyphenyl]-3-phenylpropan-1-one Show/Hide	C30H36N2O4	1
1	EC50 = 177.83 nM Bioactivity Info	TI LI LO TS
CP0949375 Compound Info	(1R)-2-[4-(2-methoxyphenyl)piperazin-1-yl]-1-[3-(2-phenylethyl)-1-benzofuran-2-yl]ethanol Show/Hide	C29H32N2O3	1
1	EC50 = 177.83 nM Bioactivity Info	TI LI LO TS
CP0915100 Compound Info	(1S)-1-[2-[(2R)-3-(4-benzylpiperazin-1-yl)-2-hydroxypropoxy]phenyl]-3-phenylpropan-1-ol Show/Hide	C29H36N2O3	1
1	EC50 = 186.21 nM Bioactivity Info	TI LI LO TS
CP0444390 Compound Info	1-(2-(4-(4-(4-fluorophenyl)piperazin-1-yl)butoxy)phenyl)-3-phenylpropan-1-one Show/Hide	C29H33FN2O2	1
1	EC50 = 190.55 nM Bioactivity Info	TI LI LO TS
CP0852431 Compound Info	1-[3-[(2R)-3-(3,3-diphenylpropylamino)-2-hydroxypropoxy]phenyl]-3-phenylpropan-1-one Show/Hide	C33H35NO3	1
1	EC50 = 190.55 nM Bioactivity Info	TI LI LO TS
CP0933742 Compound Info	1-[2-[(2R)-3-[4-(2,3-dimethylphenyl)piperazin-1-yl]-2-hydroxypropoxy]phenyl]ethanone Show/Hide	C23H30N2O3	1
1	EC50 = 199.53 nM Bioactivity Info	TI LI LO TS
CP0503966 Compound Info	3-phenyl-1-(2-(6-(piperidin-1-yl)hexyloxy)phenyl)propan-1-one Show/Hide	C26H35NO2	1
1	EC50 = 204.17 nM Bioactivity Info	TI LI LO TS
CP0911603 Compound Info	[3-[(2R)-2-hydroxy-3-[4-(2-methylphenyl)piperazin-1-yl]propoxy]phenyl]-phenylmethanone Show/Hide	C27H30N2O3	1
1	EC50 = 204.17 nM Bioactivity Info	TI LI LO TS
CP0939947 Compound Info	1-[5-acetyl-4-[(2R)-2-hydroxy-3-[4-(2-methylphenyl)piperazin-1-yl]propoxy]-2-methylphenyl]ethanone Show/Hide	C25H32N2O4	1
1	EC50 = 208.93 nM Bioactivity Info	TI LI LO TS
CP0948382 Compound Info	1-[2-[(2R)-2-hydroxy-3-[[(1S)-2-methyl-1-phenylpropyl]amino]propoxy]phenyl]-3-phenylpropan-1-one Show/Hide	C28H33NO3	1
1	EC50 = 208.93 nM Bioactivity Info	TI LI LO TS
CP0905120 Compound Info	(2S)-2-benzyl-7-[(2R)-2-hydroxy-3-piperidin-1-ylpropoxy]-2,3-dihydroinden-1-one Show/Hide	C24H29NO3	1
1	EC50 = 213.8 nM Bioactivity Info	TI LI LO TS
CP0942743 Compound Info	(2R)-1-[4-(4-fluorophenyl)piperazin-1-yl]-3-[2-[(1R)-1-methoxy-3-phenylpropyl]phenoxy]propan-2-ol Show/Hide	C29H35FN2O3	1
1	EC50 = 223.87 nM Bioactivity Info	TI LI LO TS
CP0902343 Compound Info	1-[2-[(2R)-2-hydroxy-3-[4-(2-methoxyphenyl)piperazin-1-yl]propoxy]phenyl]-3-phenylpropan-1-one Show/Hide	C29H34N2O4	1
1	EC50 = 229.09 nM Bioactivity Info	TI LI LO TS
CP0903985 Compound Info	1-[4-[(2R)-3-[4-(2,3-dimethylphenyl)piperazin-1-yl]-2-hydroxypropoxy]phenyl]-3-phenylpropan-1-one Show/Hide	C30H36N2O3	1
1	EC50 = 229.09 nM Bioactivity Info	TI LI LO TS
CP0522690 Compound Info	3-phenyl-1-(2-(5-(piperidin-1-yl)pentyloxy)phenyl)propan-1-one Show/Hide	C25H33NO2	1
1	EC50 = 239.88 nM Bioactivity Info	TI LI LO TS
CP0915091 Compound Info	1-[2-[(2R)-3-[4-(4-fluorophenyl)piperazin-1-yl]-2-hydroxypropoxy]-5-methylphenyl]-3-phenylpropan-1-one Show/Hide	C29H33FN2O3	1
1	EC50 = 245.47 nM Bioactivity Info	TI LI LO TS
CP0870291 Compound Info	1-[2-[(2R)-2-hydroxy-3-[4-(2-methylphenyl)piperazin-1-yl]propoxy]phenyl]ethanone Show/Hide	C22H28N2O3	1
1	EC50 = 251.19 nM Bioactivity Info	TI LI LO TS
CP0848611 Compound Info	1-[2-[(2R)-2-hydroxy-3-[4-(4-methoxyphenyl)piperazin-1-yl]propoxy]phenyl]-3-phenylpropan-1-one Show/Hide	C29H34N2O4	1
1	EC50 = 257.04 nM Bioactivity Info	TI LI LO TS
CP0870318 Compound Info	1-[2-[(2R)-3-(4-benzylpiperidin-1-yl)-2-hydroxypropoxy]phenyl]-3-phenylpropan-1-one Show/Hide	C30H35NO3	1
1	EC50 = 257.04 nM Bioactivity Info	TI LI LO TS
CP0875950 Compound Info	1-[3-[(2R)-3-[4-(2,3-dimethylphenyl)piperazin-1-yl]-2-hydroxypropoxy]phenyl]-3-naphthalen-1-ylpropan-1-one Show/Hide	C34H38N2O3	1
1	EC50 = 263.03 nM Bioactivity Info	TI LI LO TS
CP0947510 Compound Info	1-[4-[(2R)-2-hydroxy-3-piperidin-1-ylpropoxy]phenyl]-3-naphthalen-1-ylpropan-1-one Show/Hide	C27H31NO3	1
1	EC50 = 263.03 nM Bioactivity Info	TI LI LO TS
CP0948383 Compound Info	1-[2-[(2R)-2-hydroxy-3-piperidin-1-ylpropoxy]-5-methylphenyl]-3-phenylpropan-1-one Show/Hide	C24H31NO3	1
1	EC50 = 263.03 nM Bioactivity Info	TI LI LO TS
CP0425013 Compound Info	N-[2-[(3-acetyl-2,4,6-trimethylphenyl)methylsulfanyl]-1,3-benzothiazol-6-yl]-4-tert-butylbenzamide Show/Hide	C30H32N2O2S2	1
1	EC50 = 281.84 nM Bioactivity Info	TI LI LO TS
CP0933682 Compound Info	1-[2-[(2R)-2-hydroxy-3-(propylamino)propoxy]phenyl]-3-phenylpropan-1-one Show/Hide	C21H27NO3	1
1	EC50 = 281.84 nM Bioactivity Info	TI LI LO TS
CP0918318 Compound Info	(2R)-3-[4-[(2S)-butan-2-yl]phenyl]-2-(4-propan-2-ylphenyl)-1,2-dihydroquinazolin-4-one Show/Hide	C27H30N2O	1
1	EC50 = 288.4 nM Bioactivity Info	TI LI LO TS
CP0856355 Compound Info	1-[2-[(2R)-3-[[(1R)-2,2-dimethyl-1-phenylpropyl]amino]-2-hydroxypropoxy]phenyl]-3-phenylpropan-1-one Show/Hide	C29H35NO3	1
1	EC50 = 295.12 nM Bioactivity Info	TI LI LO TS
CP0870326 Compound Info	1-[2-[(2R)-2-hydroxy-3-piperidin-1-ylpropoxy]-4-methoxyphenyl]-3-phenylpropan-1-one Show/Hide	C24H31NO4	1
1	EC50 = 295.12 nM Bioactivity Info	TI LI LO TS
CP0942744 Compound Info	(2S)-2-benzyl-7-[(2R)-2-hydroxy-3-morpholin-4-ylpropoxy]-2,3-dihydroinden-1-one Show/Hide	C23H27NO4	1
1	EC50 = 295.12 nM Bioactivity Info	TI LI LO TS
CP0425010 Compound Info	N-[2-[(3-acetyl-2,4,6-trimethylphenyl)methylsulfanyl]-1,3-benzothiazol-6-yl]-3-phenylpropanamide Show/Hide	C28H28N2O2S2	1
1	EC50 = 302 nM Bioactivity Info	TI LI LO TS
CP0848615 Compound Info	1-[2-[(2R)-2-hydroxy-3-(4-hydroxy-4-phenylpiperidin-1-yl)propoxy]phenyl]propan-1-one Show/Hide	C23H29NO4	1
1	EC50 = 302 nM Bioactivity Info	TI LI LO TS
CP0856354 Compound Info	[2-[(2R)-2-hydroxy-3-(4-hydroxy-4-phenylpiperidin-1-yl)propoxy]phenyl]-phenylmethanone Show/Hide	C27H29NO4	1
1	EC50 = 309.03 nM Bioactivity Info	TI LI LO TS
CP0957070 Compound Info	(E)-1-[2-[(2R)-2-hydroxy-3-piperidin-1-ylpropoxy]phenyl]-3-phenylprop-2-en-1-one Show/Hide	C23H27NO3	1
1	EC50 = 316.23 nM Bioactivity Info	TI LI LO TS
CP0011846 Compound Info	1-(2-(2-hydroxy-3-(propylamino)propoxy)phenyl)-3-phenylpropan-1-one Show/Hide	C21H27NO3	1
1	EC50 = 331.13 nM Bioactivity Info	TI LI LO TS
CP0942733 Compound Info	[(2R,3S,4R)-4-[[(2S)-5-(diethylamino)pentan-2-yl]amino]-2-methyl-1,2,3,4-tetrahydroquinolin-3-yl] 4-methylbenzoate Show/Hide	C27H39N3O2	1
1	EC50 = 331.13 nM Bioactivity Info	TI LI LO TS
CP0947509 Compound Info	1-[2-[(2R)-3-[4-(2,3-dimethylphenyl)piperazin-1-yl]-2-hydroxypropoxy]-5-methylphenyl]ethanone Show/Hide	C24H32N2O3	1
1	EC50 = 331.13 nM Bioactivity Info	TI LI LO TS
CP0856351 Compound Info	1-[2-[(2R)-3-(cyclohexylamino)-2-hydroxypropoxy]phenyl]-3-phenylpropan-1-one Show/Hide	C24H31NO3	1
1	EC50 = 338.84 nM Bioactivity Info	TI LI LO TS
CP0902347 Compound Info	[(2R)-1-[2-(3-phenylpropanoyl)phenoxy]-3-piperidin-1-ylpropan-2-yl] acetate Show/Hide	C25H31NO4	1
1	EC50 = 338.84 nM Bioactivity Info	TI LI LO TS
CP0933741 Compound Info	1-[2-[(2R)-3-(4-benzylpiperidin-1-yl)-2-hydroxypropoxy]phenyl]ethanone Show/Hide	C23H29NO3	1
1	EC50 = 354.81 nM Bioactivity Info	TI LI LO TS
CP0866602 Compound Info	1-[2-[(2R)-3-[di(propan-2-yl)amino]-2-hydroxypropoxy]phenyl]-3-phenylpropan-1-one Show/Hide	C24H33NO3	1
1	EC50 = 380.19 nM Bioactivity Info	TI LI LO TS
CP0870325 Compound Info	1-[3-[(2R)-3-[4-(2,3-dimethylphenyl)piperazin-1-yl]-2-hydroxypropoxy]phenyl]ethanone Show/Hide	C23H30N2O3	1
1	EC50 = 380.19 nM Bioactivity Info	TI LI LO TS
CP0876182 Compound Info	4-[(2R)-3-(2-benzoylphenoxy)-2-hydroxypropyl]-N-(4-methylphenyl)piperazine-1-carbothioamide Show/Hide	C28H31N3O3S	1
1	EC50 = 380.19 nM Bioactivity Info	TI LI LO TS
CP0910809 Compound Info	(2S)-2-benzyl-7-[(2R)-2-hydroxy-3-[4-(4-methoxyphenyl)piperazin-1-yl]propoxy]-2,3-dihydroinden-1-one Show/Hide	C30H34N2O4	1
1	EC50 = 389.05 nM Bioactivity Info	TI LI LO TS
CP0848195 Compound Info	(2R)-1-[2-[(1R)-1-[(2-methylpropan-2-yl)oxy]-3-phenylpropyl]phenoxy]-3-piperidin-1-ylpropan-2-ol Show/Hide	C27H39NO3	1
1	EC50 = 398.11 nM Bioactivity Info	TI LI LO TS
CP0912170 Compound Info	1-[2-[(2R)-2-hydroxy-3-[4-(2-methylphenyl)piperazin-1-yl]propoxy]-5-methylphenyl]ethanone Show/Hide	C23H30N2O3	1
1	EC50 = 398.11 nM Bioactivity Info	TI LI LO TS
CP0948702 Compound Info	1-[4-[(2R)-2-hydroxy-3-[4-(2-methylphenyl)piperazin-1-yl]propoxy]phenyl]-3-naphthalen-1-ylpropan-1-one Show/Hide	C33H36N2O3	1
1	EC50 = 407.38 nM Bioactivity Info	TI LI LO TS
CP0848612 Compound Info	1-[2-[(2R)-2-hydroxy-3-[methyl(propyl)amino]propoxy]phenyl]-3-phenylpropan-1-one Show/Hide	C22H29NO3	1
1	EC50 = 416.87 nM Bioactivity Info	TI LI LO TS
CP0888658 Compound Info	1-[3-[(2R)-2-hydroxy-3-piperidin-1-ylpropoxy]phenyl]-3-phenylpropan-1-one Show/Hide	C23H29NO3	1
1	EC50 = 426.58 nM Bioactivity Info	TI LI LO TS
CP0948389 Compound Info	[(2R,3S,4S)-4-(4-benzylpiperazin-1-yl)-3-hydroxy-2-methyl-3,4-dihydro-2H-quinolin-1-yl]-(4-methylphenyl)methanone Show/Hide	C29H33N3O2	1
1	EC50 = 426.58 nM Bioactivity Info	TI LI LO TS
CP0963483 Compound Info	[4-[(2R)-3-[di(propan-2-yl)amino]-2-hydroxypropoxy]phenyl]-phenylmethanone Show/Hide	C22H29NO3	1
1	EC50 = 436.52 nM Bioactivity Info	TI LI LO TS
CP0856353 Compound Info	(2R)-1-[2-[(1R)-3-phenyl-1-propan-2-yloxypropyl]phenoxy]-3-piperidin-1-ylpropan-2-ol Show/Hide	C26H37NO3	1
1	EC50 = 457.09 nM Bioactivity Info	TI LI LO TS
CP0852390 Compound Info	1-[2-[(2R)-3-[di(propan-2-yl)amino]-2-hydroxypropoxy]phenyl]-3-naphthalen-1-ylpropan-1-one Show/Hide	C28H35NO3	1
1	EC50 = 467.74 nM Bioactivity Info	TI LI LO TS
CP0650011 Compound Info	SID50100315 Show/Hide	C21H27NO3	1
1	EC50 = 478.63 nM Bioactivity Info	TI LI LO TS
CP0957632 Compound Info	1-[4-[(2R)-3-[4-(2,3-dimethylphenyl)piperazin-1-yl]-2-hydroxypropoxy]phenyl]-3-naphthalen-1-ylpropan-1-one Show/Hide	C34H38N2O3	1
1	EC50 = 478.63 nM Bioactivity Info	TI LI LO TS
CP0957635 Compound Info	4-[(2R)-3-(2-benzoylphenoxy)-2-hydroxypropyl]-N-(4-methylphenyl)piperazine-1-carboxamide Show/Hide	C28H31N3O4	1
1	EC50 = 478.63 nM Bioactivity Info	TI LI LO TS
CP0942734 Compound Info	[4-[(2R)-2-hydroxy-3-[4-(2-methylphenyl)piperazin-1-yl]propoxy]phenyl]-phenylmethanone Show/Hide	C27H30N2O3	1
1	EC50 = 501.19 nM Bioactivity Info	TI LI LO TS
CP0963489 Compound Info	1-[4-[(2R)-3-(3,3-diphenylpropylamino)-2-hydroxypropoxy]phenyl]-3-phenylpropan-1-one Show/Hide	C33H35NO3	1
1	EC50 = 501.19 nM Bioactivity Info	TI LI LO TS
CP0869418 Compound Info	1-[2-[(2R)-3-(4-benzylpiperazin-1-yl)-2-hydroxypropoxy]-5-hydroxyphenyl]-3-phenylpropan-1-one Show/Hide	C29H34N2O4	1
1	EC50 = 524.81 nM Bioactivity Info	TI LI LO TS
CP0483815 Compound Info	3-phenyl-1-(2-(4-(piperidin-1-yl)butoxy)phenyl)propan-1-one Show/Hide	C24H31NO2	1
1	EC50 = 537.03 nM Bioactivity Info	TI LI LO TS
CP0913304 Compound Info	1-[3-[(2R)-2-hydroxy-3-[4-(2-methylphenyl)piperazin-1-yl]propoxy]phenyl]ethanone Show/Hide	C22H28N2O3	1
1	EC50 = 537.03 nM Bioactivity Info	TI LI LO TS
CP0852383 Compound Info	tert-butyl 2-[[(3S,4R)-6-cyano-3-hydroxy-2,2-dimethyl-3,4-dihydrochromen-4-yl]amino]-3-phenylpropanoate Show/Hide	C25H30N2O4	1
1	EC50 = 549.54 nM Bioactivity Info	TI LI LO TS
CP0852464 Compound Info	1-[4-[(2R)-3-[4-(4-fluorophenyl)piperazin-1-yl]-2-hydroxypropoxy]phenyl]-3-naphthalen-1-ylpropan-1-one Show/Hide	C32H33FN2O3	1
1	EC50 = 549.54 nM Bioactivity Info	TI LI LO TS
CP0926357 Compound Info	[3-[(2R)-3-[4-(4-fluorophenyl)piperazin-1-yl]-2-hydroxypropoxy]phenyl]-phenylmethanone Show/Hide	C26H27FN2O3	1
1	EC50 = 575.44 nM Bioactivity Info	TI LI LO TS
CP0939998 Compound Info	1-[2-[(2R)-2-hydroxy-3-piperidin-1-ylpropoxy]phenyl]-3-phenylpropan-1-one Show/Hide	C23H29NO3	1
1	EC50 = 602.56 nM Bioactivity Info	TI LI LO TS
CP0888655 Compound Info	1-[2-[(2R)-2-hydroxy-3-(4-phenylpiperazin-1-yl)propoxy]phenyl]-3-phenylpropan-1-one Show/Hide	C28H32N2O3	1
1	EC50 = 616.6 nM Bioactivity Info	TI LI LO TS
CP0875952 Compound Info	1-[3-[(2R)-2-hydroxy-3-morpholin-4-ylpropoxy]phenyl]-3-naphthalen-1-ylpropan-1-one Show/Hide	C26H29NO4	1
1	EC50 = 630.96 nM Bioactivity Info	TI LI LO TS
CP0432626 Compound Info	3-phenyl-1-(2-(3-(piperidin-1-yl)propoxy)phenyl)propan-1-one Show/Hide	C23H29NO2	1
1	EC50 = 645.65 nM Bioactivity Info	TI LI LO TS
CP0861448 Compound Info	1-[3-(2-phenylethyl)-2,3-dihydro-1-benzofuran-2-yl]-2-piperidin-1-ylethanol Show/Hide	C23H29NO2	1
1	EC50 = 645.65 nM Bioactivity Info	TI LI LO TS
CP0888656 Compound Info	1-[2-[(2R)-3-(4-benzylpiperazin-1-yl)-2-hydroxypropoxy]phenyl]-3-phenylpropan-1-one Show/Hide	C29H34N2O3	1
1	EC50 = 660.69 nM Bioactivity Info	TI LI LO TS
CP0905113 Compound Info	[4-[(2R)-3-[4-(2,3-dimethylphenyl)piperazin-1-yl]-2-hydroxypropoxy]phenyl]-phenylmethanone Show/Hide	C28H32N2O3	1
1	EC50 = 660.69 nM Bioactivity Info	TI LI LO TS
CP0948377 Compound Info	(2R)-1-[di(propan-2-yl)amino]-3-[2-[(1R)-1-methoxy-3-phenylpropyl]phenoxy]propan-2-ol Show/Hide	C25H37NO3	1
1	EC50 = 660.69 nM Bioactivity Info	TI LI LO TS
CP0866603 Compound Info	1-[2-[(2R)-2-hydroxy-3-[4-(3-methoxyphenyl)piperazin-1-yl]propoxy]phenyl]-3-phenylpropan-1-one Show/Hide	C29H34N2O4	1
1	EC50 = 676.08 nM Bioactivity Info	TI LI LO TS
CP0875946 Compound Info	(1R)-1-[2-[(2R)-3-[4-(4-fluorophenyl)piperazin-1-yl]-2-hydroxypropoxy]phenyl]-3-phenylpropan-1-ol Show/Hide	C28H33FN2O3	1
1	EC50 = 676.08 nM Bioactivity Info	TI LI LO TS
CP0912172 Compound Info	(4Z)-5-methyl-4-[[4-(2-methylphenyl)piperazin-1-yl]-phenylmethylidene]-2-phenylpyrazol-3-one Show/Hide	C28H28N4O	1
1	EC50 = 676.08 nM Bioactivity Info	TI LI LO TS
CP0848192 Compound Info	1-[2-[(2R)-3-(3,3-diphenylpropylamino)-2-hydroxypropoxy]phenyl]-3-naphthalen-1-ylpropan-1-one Show/Hide	C37H37NO3	1
1	EC50 = 724.44 nM Bioactivity Info	TI LI LO TS
CP0848194 Compound Info	1-[2-[(2R)-3-(3,3-diphenylpropylamino)-2-hydroxypropoxy]phenyl]-3-phenylpropan-1-one Show/Hide	C33H35NO3	1
1	EC50 = 724.44 nM Bioactivity Info	TI LI LO TS
CP0918349 Compound Info	1-[2-[(2R)-2-hydroxy-3-morpholin-4-ylpropoxy]phenyl]-3-naphthalen-1-ylpropan-1-one Show/Hide	C26H29NO4	1
1	EC50 = 724.44 nM Bioactivity Info	TI LI LO TS
CP0856358 Compound Info	(2R)-2-(1,3-benzodioxol-5-yl)-3-(4-tert-butylphenyl)-1,2-dihydroquinazolin-4-one Show/Hide	C25H24N2O3	1
1	EC50 = 741.31 nM Bioactivity Info	TI LI LO TS
CP0915102 Compound Info	(2R)-3-[4-[(2S)-butan-2-yl]phenyl]-2-(4-methoxyphenyl)-1,2-dihydroquinazolin-4-one Show/Hide	C25H26N2O2	1
1	EC50 = 758.58 nM Bioactivity Info	TI LI LO TS
CP0948378 Compound Info	(2R)-1-(3,3-diphenylpropylamino)-3-[2-[(1R)-1-methoxy-3-phenylpropyl]phenoxy]propan-2-ol Show/Hide	C34H39NO3	1
1	EC50 = 758.58 nM Bioactivity Info	TI LI LO TS
CP0948695 Compound Info	tert-butyl 2-[[(3R,4S)-6-cyano-3-hydroxy-2,2-dimethyl-3,4-dihydrochromen-4-yl]amino]-3-phenylpropanoate Show/Hide	C25H30N2O4	1
1	EC50 = 776.25 nM Bioactivity Info	TI LI LO TS
CP0912167 Compound Info	1-[2-[(2R)-3-(2,2-diphenylethylamino)-2-hydroxypropoxy]phenyl]-3-phenylpropan-1-one Show/Hide	C32H33NO3	1
1	EC50 = 794.33 nM Bioactivity Info	TI LI LO TS
CP0866589 Compound Info	1-[3-[(2R)-2-hydroxy-3-(propylamino)propoxy]thiophen-2-yl]-3-phenylpropan-1-one Show/Hide	C19H25NO3S	1
1	EC50 = 812.83 nM Bioactivity Info	TI LI LO TS
CP0939948 Compound Info	1-[2-[(2R)-3-[4-(4-fluorophenyl)piperazin-1-yl]-2-hydroxypropoxy]phenyl]propan-1-one Show/Hide	C22H27FN2O3	1
1	EC50 = 831.76 nM Bioactivity Info	TI LI LO TS
CP0903986 Compound Info	1-[2-[(2R)-2-hydroxy-3-[4-(2-methylphenyl)piperazin-1-yl]propoxy]-5-methoxyphenyl]ethanone Show/Hide	C23H30N2O4	1
1	EC50 = 851.14 nM Bioactivity Info	TI LI LO TS
CP0910800 Compound Info	(3R,4S)-4-(4-benzylpiperazin-1-yl)-3-hydroxy-2,2-dimethyl-3,4-dihydrochromene-6-carbonitrile Show/Hide	C23H27N3O2	1
1	EC50 = 851.14 nM Bioactivity Info	TI LI LO TS
CP0931877 Compound Info	(1R)-1-[2-[(2R)-2-hydroxy-3-piperidin-1-ylpropoxy]phenyl]-3-phenylpropan-1-ol Show/Hide	C23H31NO3	1
1	EC50 = 851.14 nM Bioactivity Info	TI LI LO TS
CP0852433 Compound Info	1-[4-[(2R)-2-hydroxy-3-[4-(2-methylphenyl)piperazin-1-yl]propoxy]phenyl]propan-1-one Show/Hide	C23H30N2O3	1
1	EC50 = 870.96 nM Bioactivity Info	TI LI LO TS
CP0918351 Compound Info	tert-butyl 4-[(2R)-3-(2-benzoylphenoxy)-2-hydroxypropyl]piperazine-1-carboxylate Show/Hide	C25H32N2O5	1
1	EC50 = 870.96 nM Bioactivity Info	TI LI LO TS
CP0942737 Compound Info	(1S)-1-[2-[(2R)-2-hydroxy-3-piperidin-1-ylpropoxy]phenyl]-3-phenylpropan-1-ol Show/Hide	C23H31NO3	1
1	EC50 = 870.96 nM Bioactivity Info	TI LI LO TS
CP0383408 Compound Info	1-(2-(2-hydroxy-3-(piperidin-1-yl)propoxy)phenyl)-3-phenylpropan-1-ol Show/Hide	C23H31NO3	1
1	EC50 = 891.25 nM Bioactivity Info	TI LI LO TS
CP0912173 Compound Info	4-benzoyl-1-[(2R)-2-hydroxy-3-[4-(2-methylphenyl)piperazin-1-yl]propyl]-5-methyl-2-phenylpyrazol-3-one Show/Hide	C31H34N4O3	1
1	EC50 = 891.25 nM Bioactivity Info	TI LI LO TS
CP0912166 Compound Info	1-[4-[(2R)-3-[di(propan-2-yl)amino]-2-hydroxypropoxy]phenyl]-3-phenylpropan-1-one Show/Hide	C24H33NO3	1
1	EC50 = 912.01 nM Bioactivity Info	TI LI LO TS
CP0939997 Compound Info	1-[2-[(2R)-3-(diethylamino)-2-hydroxypropoxy]phenyl]-3-phenylpropan-1-one Show/Hide	C22H29NO3	1
1	EC50 = 912.01 nM Bioactivity Info	TI LI LO TS
CP0902339 Compound Info	tert-butyl (2S)-2-[[(3S,4R)-6-cyano-3-hydroxy-2,2-dimethyl-3,4-dihydrochromen-4-yl]-methylamino]-3-methylbutanoate Show/Hide	C22H32N2O4	1
1	EC50 = 954.99 nM Bioactivity Info	TI LI LO TS
CP0856349 Compound Info	1-[4-[(2R)-2-hydroxy-3-piperidin-1-ylpropoxy]phenyl]-3-phenylpropan-1-one Show/Hide	C23H29NO3	1
1	EC50 = 977.24 nM Bioactivity Info	TI LI LO TS
CP0915093 Compound Info	tert-butyl (2R)-2-[[(3R,4S)-6-cyano-3-hydroxy-2,2-dimethyl-3,4-dihydrochromen-4-yl]-methylamino]-3-methylbutanoate Show/Hide	C22H32N2O4	1
1	EC50 = 977.24 nM Bioactivity Info	TI LI LO TS
CP0939951 Compound Info	[4-[(2R)-3-[4-(4-fluorophenyl)piperazin-1-yl]-2-hydroxypropoxy]phenyl]-phenylmethanone Show/Hide	C26H27FN2O3	1
1	EC50 = 977.24 nM Bioactivity Info	TI LI LO TS
CP0380586 Compound Info	1-(2-(4-morpholinobutoxy)phenyl)-3-phenylpropan-1-one Show/Hide	C23H29NO3	1
1	EC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0912160 Compound Info	tert-butyl (2R)-2-[[(3S,4R)-6-cyano-3-hydroxy-2,2-dimethyl-3,4-dihydrochromen-4-yl]-methylamino]-3-methylbutanoate Show/Hide	C22H32N2O4	1
1	EC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0939957 Compound Info	(2R)-2-(4-methoxyphenyl)-3-(4-phenoxyphenyl)-1,2-dihydroquinazolin-4-one Show/Hide	C27H22N2O3	1
1	EC50 = 1000 nM Bioactivity Info	TI LI LO TS
CP0444387 Compound Info	(S)-1-(3-phenethylbenzofuran-2-yl)-2-(propylamino)ethanol Show/Hide	C21H25NO2	1
1	EC50 = 1047.13 nM Bioactivity Info	TI LI LO TS
CP0949377 Compound Info	1-[2-[(2R)-3-[di(propan-2-yl)amino]-2-hydroxypropoxy]-5-hydroxyphenyl]-3-phenylpropan-1-one Show/Hide	C24H33NO4	1
1	EC50 = 1047.13 nM Bioactivity Info	TI LI LO TS
CP0483814 Compound Info	(R)-1-(3-phenethylbenzofuran-2-yl)-2-(propylamino)ethanol Show/Hide	C21H25NO2	1
1	EC50 = 1096.48 nM Bioactivity Info	TI LI LO TS
CP0902345 Compound Info	1-[3-[(2R)-3-[4-(4-fluorophenyl)piperazin-1-yl]-2-hydroxypropoxy]phenyl]-3-phenylpropan-1-one Show/Hide	C28H31FN2O3	1
1	EC50 = 1122.02 nM Bioactivity Info	TI LI LO TS
CP0913302 Compound Info	[2-[(2R)-2-hydroxy-3-(propylamino)propoxy]-5-methylphenyl]-phenylmethanone Show/Hide	C20H25NO3	1
1	EC50 = 1202.26 nM Bioactivity Info	TI LI LO TS
CP0942728 Compound Info	[5-[(2R)-3-[di(propan-2-yl)amino]-2-hydroxypropoxy]-1,3-dimethylpyrazol-4-yl]-phenylmethanone Show/Hide	C21H31N3O3	1
1	EC50 = 1202.26 nM Bioactivity Info	TI LI LO TS
CP0949625 Compound Info	(2R)-3-(4-ethylphenyl)-2-[4-(2-methylpropoxy)phenyl]-1,2-dihydroquinazolin-4-one Show/Hide	C26H28N2O2	1
1	EC50 = 1202.26 nM Bioactivity Info	TI LI LO TS
CP0852427 Compound Info	1-[4-[(2R)-3-[4-(2,3-dimethylphenyl)piperazin-1-yl]-2-hydroxypropoxy]phenyl]ethanone Show/Hide	C23H30N2O3	1
1	EC50 = 1348.96 nM Bioactivity Info	TI LI LO TS
CP0910377 Compound Info	tert-butyl (2R)-2-[[(3R,4S)-3-hydroxy-2,2-dimethyl-3,4-dihydrochromen-4-yl]amino]-3-methylbutanoate Show/Hide	C20H31NO4	1
1	EC50 = 1348.96 nM Bioactivity Info	TI LI LO TS
CP0949626 Compound Info	tert-butyl (2S)-2-[[(3R,4S)-6-cyano-3-hydroxy-2,2-dimethyl-3,4-dihydrochromen-4-yl]-methylamino]-3-methylbutanoate Show/Hide	C22H32N2O4	1
1	EC50 = 1348.96 nM Bioactivity Info	TI LI LO TS
CP0848199 Compound Info	[(2R,3S,4R)-4-[benzyl(2-hydroxyethyl)amino]-3-hydroxy-2-methyl-3,4-dihydro-2H-quinolin-1-yl]-(4-methylphenyl)methanone Show/Hide	C27H30N2O3	1
1	EC50 = 1380.38 nM Bioactivity Info	TI LI LO TS
CP0957078 Compound Info	1-[4-[(2R)-3-[4-(2,3-dimethylphenyl)piperazin-1-yl]-2-hydroxypropoxy]phenyl]propan-1-one Show/Hide	C24H32N2O3	1
1	EC50 = 1412.54 nM Bioactivity Info	TI LI LO TS
CP0464358 Compound Info	3-phenyl-1-(2-(2-(piperidin-1-yl)ethoxy)phenyl)propan-1-one Show/Hide	C22H27NO2	1
1	EC50 = 1445.44 nM Bioactivity Info	TI LI LO TS
CP0942725 Compound Info	1-[4-[(2R)-3-[4-(4-fluorophenyl)piperazin-1-yl]-2-hydroxypropoxy]phenyl]propan-1-one Show/Hide	C22H27FN2O3	1
1	EC50 = 1445.44 nM Bioactivity Info	TI LI LO TS
CP0948700 Compound Info	1-[2-[(2R)-3-(4-benzylpiperazin-1-yl)-2-hydroxypropoxy]phenyl]propan-1-one Show/Hide	C23H30N2O3	1
1	EC50 = 1445.44 nM Bioactivity Info	TI LI LO TS
CP0910802 Compound Info	(1R)-1-[2-[(2S)-2-hydroxy-3-piperidin-1-ylpropoxy]phenyl]-3-phenylpropan-1-ol Show/Hide	C23H31NO3	1
1	EC50 = 1513.56 nM Bioactivity Info	TI LI LO TS
CP0852425 Compound Info	methyl 4-[[(2R)-2-hydroxy-3-[2-(3-phenylpropanoyl)phenoxy]propyl]amino]benzoate Show/Hide	C26H27NO5	1
1	EC50 = 1548.82 nM Bioactivity Info	TI LI LO TS
CP0939138 Compound Info	1-[4-[(2R)-2-hydroxy-3-[4-(2-methylphenyl)piperazin-1-yl]propoxy]phenyl]ethanone Show/Hide	C22H28N2O3	1
1	EC50 = 1548.82 nM Bioactivity Info	TI LI LO TS
CP0942726 Compound Info	1-[4-[(2R)-2-hydroxy-3-morpholin-4-ylpropoxy]phenyl]-3-naphthalen-1-ylpropan-1-one Show/Hide	C26H29NO4	1
1	EC50 = 1548.82 nM Bioactivity Info	TI LI LO TS
CP0939946 Compound Info	1-[[(2R,3S)-3-(2-phenylethyl)-2,3-dihydro-1-benzofuran-2-yl]methyl]piperidine Show/Hide	C22H27NO	1
1	EC50 = 1621.81 nM Bioactivity Info	TI LI LO TS
CP0848196 Compound Info	N-benzyl-N-[(2R)-2-hydroxy-3-[2-(3-phenylpropanoyl)phenoxy]propyl]propanamide Show/Hide	C28H31NO4	1
1	EC50 = 1659.59 nM Bioactivity Info	TI LI LO TS
CP0848618 Compound Info	1-[2-[(2R)-2-hydroxy-3-morpholin-4-ylpropoxy]-5-methylphenyl]-3-phenylpropan-1-one Show/Hide	C23H29NO4	1
1	EC50 = 1659.59 nM Bioactivity Info	TI LI LO TS
CP0895625 Compound Info	(1S)-1-[2-[(2S)-2-hydroxy-3-piperidin-1-ylpropoxy]phenyl]-3-phenylpropan-1-ol Show/Hide	C23H31NO3	1
1	EC50 = 1698.24 nM Bioactivity Info	TI LI LO TS
CP0948697 Compound Info	N-[(2R)-2-hydroxy-3-[2-(3-phenylpropanoyl)phenoxy]propyl]-N-propylbenzamide Show/Hide	C28H31NO4	1
1	EC50 = 1698.24 nM Bioactivity Info	TI LI LO TS
CP0848193 Compound Info	1-[5-hydroxy-2-[(2R)-2-hydroxy-3-piperidin-1-ylpropoxy]phenyl]-3-phenylpropan-1-one Show/Hide	C23H29NO4	1
1	EC50 = 1737.8 nM Bioactivity Info	TI LI LO TS
CP0852389 Compound Info	(1R)-1-[2-[(2R)-3-[di(propan-2-yl)amino]-2-hydroxypropoxy]phenyl]-3-phenylpropan-1-ol Show/Hide	C24H35NO3	1
1	EC50 = 1737.8 nM Bioactivity Info	TI LI LO TS
CP0866590 Compound Info	tert-butyl (2S)-2-[[(3R,4S)-6-cyano-3-hydroxy-2,2-dimethyl-3,4-dihydrochromen-4-yl]amino]-3-methylbutanoate Show/Hide	C21H30N2O4	1
1	EC50 = 1778.28 nM Bioactivity Info	TI LI LO TS
CP0852426 Compound Info	N-[2-[[(2R)-3-(2-benzoylphenoxy)-2-hydroxypropyl]-methylamino]ethyl]-5-(dimethylamino)-N-methylnaphthalene-1-sulfonamide Show/Hide	C32H37N3O5S	1
1	EC50 = 1819.7 nM Bioactivity Info	TI LI LO TS
CP0933740 Compound Info	(2R)-1-[2-[(1R)-1-methoxy-3-phenylpropyl]phenoxy]-3-morpholin-4-ylpropan-2-ol Show/Hide	C23H31NO4	1
1	EC50 = 1819.7 nM Bioactivity Info	TI LI LO TS
CP0915101 Compound Info	tert-butyl 2-[benzyl-[(3R,4S)-6-cyano-3-hydroxy-2,2-dimethyl-3,4-dihydrochromen-4-yl]amino]acetate Show/Hide	C25H30N2O4	1
1	EC50 = 1995.26 nM Bioactivity Info	TI LI LO TS
CP0949380 Compound Info	(2R)-2-[[4-(2,3-dimethylphenyl)piperazin-1-yl]methyl]-2,3-dihydrochromen-4-one Show/Hide	C22H26N2O2	1
1	EC50 = 2041.74 nM Bioactivity Info	TI LI LO TS
CP0395443 Compound Info	1-(2-(3-(4-(4-fluorophenyl)piperazin-1-yl)-2-hydroxypropoxy)phenyl)ethanone Show/Hide	C21H25FN2O3	1
1	EC50 = 2089.3 nM Bioactivity Info	TI LI LO TS
CP0852463 Compound Info	[4-[(2R)-2-hydroxy-3-piperidin-1-ylpropoxy]phenyl]-phenylmethanone Show/Hide	C21H25NO3	1
1	EC50 = 2187.76 nM Bioactivity Info	TI LI LO TS
CP0942738 Compound Info	(3S,4R)-4-[[(2S)-1-chloro-3-methylbutan-2-yl]-methylamino]-3-hydroxy-2,2-dimethyl-3,4,4a,8a-tetrahydrochromene-6-carbonitrile Show/Hide	C18H27ClN2O2	1
1	EC50 = 2238.72 nM Bioactivity Info	TI LI LO TS
CP0856327 Compound Info	[2-[(2R)-3-(diethylamino)-2-hydroxypropoxy]phenyl]-phenylmethanone Show/Hide	C20H25NO3	1
1	EC50 = 2344.23 nM Bioactivity Info	TI LI LO TS
CP0957068 Compound Info	1-[2-[(2R)-3-(dimethylamino)-2-hydroxypropoxy]phenyl]-3-phenylpropan-1-one Show/Hide	C20H25NO3	1
1	EC50 = 2454.71 nM Bioactivity Info	TI LI LO TS
CP0910807 Compound Info	1-[4-[(2R)-3-[4-(4-fluorophenyl)piperazin-1-yl]-2-hydroxypropoxy]phenyl]-3-phenylpropan-1-one Show/Hide	C28H31FN2O3	1
1	EC50 = 2511.89 nM Bioactivity Info	TI LI LO TS
CP0939941 Compound Info	1-[2-[(2R)-2-hydroxy-3-(4-nitroanilino)propoxy]phenyl]-3-phenylpropan-1-one Show/Hide	C24H24N2O5	1
1	EC50 = 2570.4 nM Bioactivity Info	TI LI LO TS
CP0848191 Compound Info	(2S)-2-[[(3R,4S)-6-cyano-3-hydroxy-2,2-dimethyl-3,4-dihydrochromen-4-yl]amino]-3-methylbutanoic acid Show/Hide	C17H22N2O4	1
1	EC50 = 2691.53 nM Bioactivity Info	TI LI LO TS
CP0888653 Compound Info	(2S,4aS,10bR)-2-benzyl-5,5-dimethyl-3-oxo-1,2,4a,10b-tetrahydrochromeno[3,4-b][1,4]oxazine-9-carbonitrile Show/Hide	C21H20N2O3	1
1	EC50 = 2691.53 nM Bioactivity Info	TI LI LO TS
CP0942732 Compound Info	[(2R,3R,4R)-4-[[(2S)-5-(diethylamino)pentan-2-yl]amino]-3-hydroxy-2-methyl-3,4-dihydro-2H-quinolin-1-yl]-(4-methylphenyl)methanone Show/Hide	C27H39N3O2	1
1	EC50 = 2691.53 nM Bioactivity Info	TI LI LO TS
CP0948387 Compound Info	1-[(2R)-3-(butylamino)-2-hydroxypropyl]-5-methyl-2-phenyl-4-(3-phenylpropanoyl)pyrazol-3-one Show/Hide	C26H33N3O3	1
1	EC50 = 2691.53 nM Bioactivity Info	TI LI LO TS
CP0888657 Compound Info	1-[5-hydroxy-2-[(2R)-2-hydroxy-3-(propylamino)propoxy]phenyl]-3-phenylpropan-1-one Show/Hide	C21H27NO4	1
1	EC50 = 3019.95 nM Bioactivity Info	TI LI LO TS
CP0869423 Compound Info	(4S)-6-amino-4-[4-(dimethylamino)phenyl]-3-(4-methylphenyl)-2,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile Show/Hide	C22H21N5O	1
1	EC50 = 3090.3 nM Bioactivity Info	TI LI LO TS
CP0915092 Compound Info	1-[2-[(2R)-2-hydroxy-3-[4-(4-methylphenyl)piperazin-1-yl]propoxy]-5-methylphenyl]ethanone Show/Hide	C23H30N2O3	1
1	EC50 = 3162.28 nM Bioactivity Info	TI LI LO TS
CP0957073 Compound Info	1-[2-[(2R)-2-hydroxy-3-(4-hydroxy-4-phenylpiperidin-1-yl)propoxy]phenyl]ethanone Show/Hide	C22H27NO4	1
1	EC50 = 3162.28 nM Bioactivity Info	TI LI LO TS
CP0942731 Compound Info	[(2R,3R,4S)-4-(benzylamino)-3-hydroxy-2-methyl-3,4-dihydro-2H-quinolin-1-yl]-(4-methylphenyl)methanone Show/Hide	C25H26N2O2	1
1	EC50 = 3235.94 nM Bioactivity Info	TI LI LO TS
CP0510224 Compound Info	2-butylsulfanyl-3-prop-2-enylspiro[6H-benzo[h]quinazoline-5,1'-cyclopentane]-4-one Show/Hide	C23H28N2OS	1
1	EC50 = 3467.37 nM Bioactivity Info	TI LI LO TS
CP0875949 Compound Info	1-[2-[(2R)-2-hydroxy-3-[4-(4-methoxyphenyl)piperazin-1-yl]propoxy]-5-methylphenyl]ethanone Show/Hide	C23H30N2O4	1
1	EC50 = 3467.37 nM Bioactivity Info	TI LI LO TS
CP0942730 Compound Info	1-[3-[(2R)-2-hydroxy-3-morpholin-4-ylpropoxy]phenyl]-3-phenylpropan-1-one Show/Hide	C22H27NO4	1
1	EC50 = 3467.37 nM Bioactivity Info	TI LI LO TS
CP0870292 Compound Info	[(2R,3S,4S)-3-hydroxy-4-[4-(2-methoxyphenyl)piperazin-1-yl]-2-methyl-3,4-dihydro-2H-quinolin-1-yl]-(4-methylphenyl)methanone Show/Hide	C29H33N3O3	1
1	EC50 = 3548.13 nM Bioactivity Info	TI LI LO TS
CP0939780 Compound Info	[3-[(2R)-2-hydroxy-3-piperidin-1-ylpropoxy]phenyl]-phenylmethanone Show/Hide	C21H25NO3	1
1	EC50 = 3548.13 nM Bioactivity Info	TI LI LO TS
CP0939949 Compound Info	1-[2-[(2R)-3-[4-(4-fluorophenyl)piperazin-1-yl]-2-hydroxypropoxy]-5-methylphenyl]ethanone Show/Hide	C22H27FN2O3	1
1	EC50 = 3630.78 nM Bioactivity Info	TI LI LO TS
CP0957071 Compound Info	1-[2-[(2R)-2-hydroxy-3-morpholin-4-ylpropoxy]phenyl]-3-phenylpropan-1-one Show/Hide	C22H27NO4	1
1	EC50 = 3630.78 nM Bioactivity Info	TI LI LO TS
CP0910379 Compound Info	tert-butyl (2S)-2-[[(3R,4S)-6-cyano-3-hydroxy-2,2-dimethyl-3,4-dihydrochromen-4-yl]-methylamino]propanoate Show/Hide	C20H28N2O4	1
1	EC50 = 3715.35 nM Bioactivity Info	TI LI LO TS
CP0963484 Compound Info	(4R)-5-methyl-2-phenyl-4-[C-(2-phenylethyl)-N-propylcarbonimidoyl]-4H-pyrazol-3-one Show/Hide	C22H25N3O	1
1	EC50 = 3715.35 nM Bioactivity Info	TI LI LO TS
CP0866601 Compound Info	tert-butyl (2S)-2-[[(3S,4R)-6-cyano-3-hydroxy-2,2-dimethyl-3,4-dihydrochromen-4-yl]-methylamino]propanoate Show/Hide	C20H28N2O4	1
1	EC50 = 3981.07 nM Bioactivity Info	TI LI LO TS
CP0869419 Compound Info	1-[2-[(2R)-3-[di(propan-2-yl)amino]-2-hydroxypropoxy]phenyl]propan-1-one Show/Hide	C18H29NO3	1
1	EC50 = 4265.8 nM Bioactivity Info	TI LI LO TS
CP0933712 Compound Info	[(2R,3S,4R)-2-methyl-4-pyrrolidin-1-yl-1,2,3,4-tetrahydroquinolin-3-yl] 4-methylbenzoate Show/Hide	C22H26N2O2	1
1	EC50 = 4677.35 nM Bioactivity Info	TI LI LO TS
CP0948397 Compound Info	tert-butyl (2R)-2-[[(3S,4R)-6-cyano-3-hydroxy-2,2-dimethyl-3,4-dihydrochromen-4-yl]amino]-3-methylbutanoate Show/Hide	C21H30N2O4	1
1	EC50 = 4677.35 nM Bioactivity Info	TI LI LO TS
CP0957067 Compound Info	(2S)-2-[[(3S,4R)-6-cyano-3-hydroxy-2,2-dimethyl-3,4-dihydrochromen-4-yl]amino]-3-methylbutanoic acid Show/Hide	C17H22N2O4	1
1	EC50 = 4786.3 nM Bioactivity Info	TI LI LO TS
CP0939954 Compound Info	(3R,4S)-4-[benzyl(2-hydroxyethyl)amino]-3-hydroxy-2,2-dimethyl-3,4-dihydrochromene-6-carbonitrile Show/Hide	C21H24N2O3	1
1	EC50 = 5370.32 nM Bioactivity Info	TI LI LO TS
CP0948384 Compound Info	[4-[(2R)-2-hydroxy-3-morpholin-4-ylpropoxy]phenyl]-phenylmethanone Show/Hide	C20H23NO4	1
1	EC50 = 5370.32 nM Bioactivity Info	TI LI LO TS
CP0444388 Compound Info	1-(2-(2-hydroxy-3-(piperidin-1-yl)propoxy)-5-methylphenyl)ethanone Show/Hide	C17H25NO3	1
1	EC50 = 5495.41 nM Bioactivity Info	TI LI LO TS
CP0912162 Compound Info	(3S,4R)-3-hydroxy-4-[[(2S)-1-hydroxy-3-methylbutan-2-yl]-methylamino]-2,2-dimethyl-3,4-dihydrochromene-6-carbonitrile Show/Hide	C18H26N2O3	1
1	EC50 = 5495.41 nM Bioactivity Info	TI LI LO TS
CP0883234 Compound Info	2-(2-chlorophenyl)-4-pyrrolidin-1-ylquinazoline Show/Hide	C18H16ClN3	1
1	EC50 = 5888.44 nM Bioactivity Info	TI LI LO TS
CP0947508 Compound Info	1-[2-[(2R)-3-[di(propan-2-yl)amino]-2-hydroxypropoxy]-5-methylphenyl]ethanone Show/Hide	C18H29NO3	1
1	EC50 = 6165.95 nM Bioactivity Info	TI LI LO TS
CP0957633 Compound Info	1-[(2R)-2-hydroxy-3-(propylamino)propyl]-5-methyl-2-phenyl-4-(3-phenylpropanoyl)pyrazol-3-one Show/Hide	C25H31N3O3	1
1	EC50 = 6309.57 nM Bioactivity Info	TI LI LO TS
CP0949376 Compound Info	1-[2-[(2R)-3-anilino-2-hydroxypropoxy]phenyl]-3-phenylpropan-1-one Show/Hide	C24H25NO3	1
1	EC50 = 6456.54 nM Bioactivity Info	TI LI LO TS
CP0848617 Compound Info	[(2R,3S)-3-(2-phenylethyl)-2,3-dihydro-1-benzofuran-2-yl]-piperidin-1-ylmethanone Show/Hide	C22H25NO2	1
1	EC50 = 6606.93 nM Bioactivity Info	TI LI LO TS
CP0875945 Compound Info	1-[4-[(2R)-2-hydroxy-3-morpholin-4-ylpropoxy]phenyl]-3-phenylpropan-1-one Show/Hide	C22H27NO4	1
1	EC50 = 6918.31 nM Bioactivity Info	TI LI LO TS
CP0931882 Compound Info	(3R,4S)-3-hydroxy-4-[(1-hydroxy-3-methylbutan-2-yl)-methylamino]-2,2-dimethyl-3,4-dihydrochromene-6-carbonitrile Show/Hide	C18H26N2O3	1
1	EC50 = 6918.31 nM Bioactivity Info	TI LI LO TS
CP0957077 Compound Info	4-[(2R)-3-(2-acetyl-4-methylphenoxy)-2-hydroxypropyl]-N-(4-methylphenyl)piperazine-1-carboxamide Show/Hide	C24H31N3O4	1
1	EC50 = 7413.1 nM Bioactivity Info	TI LI LO TS
CP0939953 Compound Info	1-[(2R)-3-(tert-butylamino)-2-hydroxypropyl]-5-methyl-2-phenyl-4-(3-phenylpropanoyl)pyrazol-3-one Show/Hide	C26H33N3O3	1
1	EC50 = 7762.47 nM Bioactivity Info	TI LI LO TS
CP0948385 Compound Info	1-[4-[(2R)-3-[di(propan-2-yl)amino]-2-hydroxypropoxy]phenyl]propan-1-one Show/Hide	C18H29NO3	1
1	EC50 = 7762.47 nM Bioactivity Info	TI LI LO TS
CP0939955 Compound Info	[(2R,3S,4R)-3-hydroxy-2-methyl-4-pyrrolidin-1-yl-3,4-dihydro-2H-quinolin-1-yl]-(4-methylphenyl)methanone Show/Hide	C22H26N2O2	1
1	EC50 = 7943.28 nM Bioactivity Info	TI LI LO TS
CP0910808 Compound Info	1-[2-[(2R)-2-hydroxy-3-[4-(trifluoromethyl)anilino]propoxy]phenyl]-3-phenylpropan-1-one Show/Hide	C25H24F3NO3	1
1	EC50 = 8511.38 nM Bioactivity Info	TI LI LO TS
CP0915099 Compound Info	(4S)-N-(2-ethoxyphenyl)-6-methyl-2-sulfanylidene-4-thiophen-2-yl-3,4-dihydro-1H-pyrimidine-5-carboxamide Show/Hide	C18H19N3O2S2	1
1	EC50 = 8709.64 nM Bioactivity Info	TI LI LO TS
CP0848616 Compound Info	(2R)-2-[(4-benzylpiperazin-1-yl)methyl]-2,3-dihydrochromen-4-one Show/Hide	C21H24N2O2	1
1	EC50 = 8912.51 nM Bioactivity Info	TI LI LO TS
CP0856357 Compound Info	[(2R,3S,4R)-4-[ethyl(2-hydroxyethyl)amino]-3-hydroxy-2-methyl-3,4-dihydro-2H-quinolin-1-yl]-(4-methylphenyl)methanone Show/Hide	C22H28N2O3	1
1	EC50 = 9120.11 nM Bioactivity Info	TI LI LO TS
CP0948380 Compound Info	1-[3-[(2R)-2-hydroxy-3-piperidin-1-ylpropoxy]phenyl]ethanone Show/Hide	C16H23NO3	1
1	EC50 = 9120.11 nM Bioactivity Info	TI LI LO TS
CP0875947 Compound Info	(1R)-1-[2-[(2R)-2-hydroxy-3-morpholin-4-ylpropoxy]phenyl]-3-phenylpropan-1-ol Show/Hide	C22H29NO4	1
1	EC50 = 9549.93 nM Bioactivity Info	TI LI LO TS
CP0957065 Compound Info	(2R,4aR,10bS)-5,5-dimethyl-3-oxo-2-propan-2-yl-1,2,4a,10b-tetrahydrochromeno[3,4-b][1,4]oxazine-9-carbonitrile Show/Hide	C17H20N2O3	1
1	EC50 = 9549.93 nM Bioactivity Info	TI LI LO TS
CP0957636 Compound Info	1-[2-[(2R)-3-[4-[(2S)-3-(2-benzoylphenoxy)-2-hydroxypropyl]piperazin-1-yl]-2-hydroxypropoxy]-5-methylphenyl]ethanone Show/Hide	C32H38N2O6	1
1	EC50 = 9549.93 nM Bioactivity Info	TI LI LO TS
CP0902352 Compound Info	7-[(2R)-2-hydroxy-3-piperidin-1-ylpropoxy]-2,3-dihydroinden-1-one Show/Hide	C17H23NO3	1
1	EC50 = 9772.37 nM Bioactivity Info	TI LI LO TS
CP0903987 Compound Info	1-[2-[(2R)-3-[di(propan-2-yl)amino]-2-hydroxypropoxy]phenyl]ethanone Show/Hide	C17H27NO3	1
1	EC50 = 10000 nM Bioactivity Info	TI LI LO TS
CP0963492 Compound Info	1-[3-[(2R)-3-[4-(4-fluorophenyl)piperazin-1-yl]-2-hydroxypropoxy]phenyl]ethanone Show/Hide	C21H25FN2O3	1
1	EC50 = 10000 nM Bioactivity Info	TI LI LO TS
CP0910381 Compound Info	1-[2-[(2R)-3-(benzhydrylamino)-2-hydroxypropoxy]phenyl]-3-phenylpropan-1-one Show/Hide	C31H31NO3	1
1	EC50 = 10471.29 nM Bioactivity Info	TI LI LO TS
CP0406058 Compound Info	(3-Methyl-1-phenyl-5-propylamino-1H-pyrazol-4-yl)-phenyl-methanone Show/Hide	C20H21N3O	1
1	EC50 = 10964.78 nM Bioactivity Info	TI LI LO TS
CP0948698 Compound Info	4-[(2R)-2-hydroxy-3-piperidin-1-ylpropoxy]-2,3-dihydroinden-1-one Show/Hide	C17H23NO3	1
1	EC50 = 11220.18 nM Bioactivity Info	TI LI LO TS
CP0875951 Compound Info	[3-[(2R)-2-hydroxy-3-morpholin-4-ylpropoxy]phenyl]-phenylmethanone Show/Hide	C20H23NO4	1
1	EC50 = 11481.54 nM Bioactivity Info	TI LI LO TS
CP0910806 Compound Info	(1R)-1-(3-ethyl-1-benzofuran-2-yl)-2-(propylamino)ethanol Show/Hide	C15H21NO2	1
1	EC50 = 11481.54 nM Bioactivity Info	TI LI LO TS
CP0918350 Compound Info	1-[4-[(2R)-3-[4-(4-fluorophenyl)piperazin-1-yl]-2-hydroxypropoxy]phenyl]ethanone Show/Hide	C21H25FN2O3	1
1	EC50 = 11748.98 nM Bioactivity Info	TI LI LO TS
CP0963486 Compound Info	1-[(2R)-2-hydroxy-3-(propan-2-ylamino)propyl]-5-methyl-2-phenyl-4-(3-phenylpropanoyl)pyrazol-3-one Show/Hide	C25H31N3O3	1
1	EC50 = 11748.98 nM Bioactivity Info	TI LI LO TS
CP0910812 Compound Info	1-[2-[(2R)-2-hydroxy-3-morpholin-4-ylpropoxy]-5-methylphenyl]ethanone Show/Hide	C16H23NO4	1
1	EC50 = 12589.25 nM Bioactivity Info	TI LI LO TS
CP0963482 Compound Info	[2-[(2R)-2-hydroxy-3-morpholin-4-ylpropoxy]phenyl]-phenylmethanone Show/Hide	C20H23NO4	1
1	EC50 = 13489.63 nM Bioactivity Info	TI LI LO TS
CP0902340 Compound Info	tert-butyl (2S)-2-[[(3R,4S)-6-cyano-3-hydroxy-2,2-dimethyl-3,4-dihydrochromen-4-yl]amino]propanoate Show/Hide	C19H26N2O4	1
1	EC50 = 14454.4 nM Bioactivity Info	TI LI LO TS
CP0912163 Compound Info	1-[2-[(2R)-2-hydroxy-3-piperidin-1-ylpropoxy]phenyl]propan-1-one Show/Hide	C17H25NO3	1
1	EC50 = 14454.4 nM Bioactivity Info	TI LI LO TS
CP0902341 Compound Info	(2S,4aS,10bR)-5,5-dimethyl-3-oxo-2-propan-2-yl-1,2,4a,10b-tetrahydrochromeno[3,4-b][1,4]oxazine-9-carbonitrile Show/Hide	C17H20N2O3	1
1	EC50 = 15488.17 nM Bioactivity Info	TI LI LO TS
CP0911604 Compound Info	4-benzoyl-1-[(2R)-3-[di(propan-2-yl)amino]-2-hydroxypropyl]-5-methyl-2-phenylpyrazol-3-one Show/Hide	C26H33N3O3	1
1	EC50 = 15848.93 nM Bioactivity Info	TI LI LO TS
CP0942740 Compound Info	(2S,4aR,10bS)-1,5,5-trimethyl-3-oxo-2-propan-2-yl-4a,10b-dihydro-2H-chromeno[3,4-b][1,4]oxazine-9-carbonitrile Show/Hide	C18H22N2O3	1
1	EC50 = 16595.87 nM Bioactivity Info	TI LI LO TS
CP0870323 Compound Info	(2R)-2-[[4-(4-fluorophenyl)piperazin-1-yl]methyl]-2,3-dihydrochromen-4-one Show/Hide	C20H21FN2O2	1
1	EC50 = 17782.79 nM Bioactivity Info	TI LI LO TS
CP0963487 Compound Info	(4aR,10bS)-1-benzyl-5,5-dimethyl-2,3,4a,10b-tetrahydrochromeno[3,4-b][1,4]oxazine-9-carbonitrile Show/Hide	C21H22N2O2	1
1	EC50 = 19498.45 nM Bioactivity Info	TI LI LO TS
CP0913278 Compound Info	N-[4-[(2R)-2-(4-methoxyphenyl)-4-oxo-1,2-dihydroquinazolin-3-yl]phenyl]acetamide Show/Hide	C23H21N3O3	1
1	EC50 = 20892.96 nM Bioactivity Info	TI LI LO TS
CP0475195 Compound Info	ethyl 2-[2-(3-phenylpropanoyl)phenoxy]acetate Show/Hide	C19H20O4	1
1	EC50 = 23442.29 nM Bioactivity Info	TI LI LO TS
CP0852465 Compound Info	1-[(2R)-3-[di(propan-2-yl)amino]-2-hydroxypropyl]-4-[(R)-hydroxy(phenyl)methyl]-5-methyl-2-phenylpyrazol-3-one Show/Hide	C26H35N3O3	1
1	EC50 = 23988.33 nM Bioactivity Info	TI LI LO TS
CP0912174 Compound Info	4-benzoyl-1-[(2R)-3-[di(propan-2-yl)amino]-2-hydroxypropyl]-2,5-dimethylpyrazol-3-one Show/Hide	C21H31N3O3	1
1	EC50 = 23988.33 nM Bioactivity Info	TI LI LO TS
CP0939956 Compound Info	(2R)-2-[4-(dimethylamino)phenyl]-3-(4-ethoxyphenyl)-1,2-dihydroquinazolin-4-one Show/Hide	C24H25N3O2	1
1	EC50 = 25118.86 nM Bioactivity Info	TI LI LO TS
CP0948513 Compound Info	(2R,4aR,10bS)-1,5,5-trimethyl-3-oxo-2-propan-2-yl-4a,10b-dihydro-2H-chromeno[3,4-b][1,4]oxazine-9-carbonitrile Show/Hide	C18H22N2O3	1
1	EC50 = 27542.29 nM Bioactivity Info	TI LI LO TS
CP0931880 Compound Info	(2S,4aR,10bS)-1,2,5,5-tetramethyl-3-oxo-4a,10b-dihydro-2H-chromeno[3,4-b][1,4]oxazine-9-carbonitrile Show/Hide	C16H18N2O3	1
1	EC50 = 28840.32 nM Bioactivity Info	TI LI LO TS
CP0910378 Compound Info	tert-butyl 2-[(6-cyano-3-hydroxy-2,2-dimethyl-3,4-dihydrochromen-4-yl)amino]propanoate Show/Hide	C19H26N2O4	1
1	EC50 = 29512.09 nM Bioactivity Info	TI LI LO TS
CP0861496 Compound Info	1-[2-[(2R)-2-hydroxy-3-piperidin-1-ylpropoxy]phenyl]ethanone Show/Hide	C16H23NO3	1
1	EC50 = 31622.78 nM Bioactivity Info	TI LI LO TS
CP0933711 Compound Info	1-[4-[(2R)-2-hydroxy-3-piperidin-1-ylpropoxy]phenyl]propan-1-one Show/Hide	C17H25NO3	1
1	EC50 = 33113.11 nM Bioactivity Info	TI LI LO TS
CP0888654 Compound Info	(3S,4R)-4-[[(2S)-1-chloro-3-methylbutan-2-yl]-methylamino]-3-hydroxy-2,2-dimethyl-3,4-dihydrochromene-6-carbonitrile Show/Hide	C18H25ClN2O2	1
1	EC50 = 35481.34 nM Bioactivity Info	TI LI LO TS
CP0910376 Compound Info	(3R,4S)-4-(benzylamino)-3-hydroxy-2,2-dimethyl-3,4-dihydrochromene-6-carbonitrile Show/Hide	C19H20N2O2	1
1	EC50 = 35481.34 nM Bioactivity Info	TI LI LO TS
CP0931883 Compound Info	(3R,4S)-4-[[(2S)-1-chloro-3-methylbutan-2-yl]-methylamino]-3-hydroxy-2,2-dimethyl-3,4-dihydrochromene-6-carbonitrile Show/Hide	C18H25ClN2O2	1
1	EC50 = 44668.36 nM Bioactivity Info	TI LI LO TS
CP0902342 Compound Info	tert-butyl (2S)-2-[[(3S,4R)-6-cyano-3-hydroxy-2,2-dimethyl-3,4-dihydrochromen-4-yl]amino]propanoate Show/Hide	C19H26N2O4	1
1	EC50 = 45708.82 nM Bioactivity Info	TI LI LO TS
CP0852468 Compound Info	tert-butyl 2-[[(3R,4S)-6-cyano-3-hydroxy-2,2-dimethyl-3,4-dihydrochromen-4-yl]amino]acetate Show/Hide	C18H24N2O4	1
1	EC50 = 46773.51 nM Bioactivity Info	TI LI LO TS
CP0912161 Compound Info	(2S,4aS,10bR)-1,2,5,5-tetramethyl-3-oxo-4a,10b-dihydro-2H-chromeno[3,4-b][1,4]oxazine-9-carbonitrile Show/Hide	C16H18N2O3	1
1	EC50 = 47863.01 nM Bioactivity Info	TI LI LO TS
CP0931881 Compound Info	(2S,4aS,10bR)-1,5,5-trimethyl-3-oxo-2-propan-2-yl-4a,10b-dihydro-2H-chromeno[3,4-b][1,4]oxazine-9-carbonitrile Show/Hide	C18H22N2O3	1
1	EC50 = 47863.01 nM Bioactivity Info	TI LI LO TS
CP0911605 Compound Info	(2R,4aR,10bS)-5,5-dimethyl-2-propan-2-yl-2,3,4a,10b-tetrahydro-1H-chromeno[3,4-b][1,4]oxazine-9-carbonitrile Show/Hide	C17H22N2O2	1
1	EC50 = 48977.88 nM Bioactivity Info	TI LI LO TS
CP0912169 Compound Info	1-[[(2R,3S)-3-methyl-2,3-dihydro-1-benzofuran-2-yl]methyl]piperidine Show/Hide	C15H21NO	1
1	EC50 = 48977.88 nM Bioactivity Info	TI LI LO TS
CP0963493 Compound Info	1-[4-[(2R)-2-hydroxy-3-piperidin-1-ylpropoxy]phenyl]ethanone Show/Hide	C16H23NO3	1
1	EC50 = 48977.88 nM Bioactivity Info	TI LI LO TS
CP0942741 Compound Info	(3S,4R)-3-hydroxy-4-[[(2S)-1-hydroxy-3-methylbutan-2-yl]amino]-2,2-dimethyl-3,4-dihydrochromene-6-carbonitrile Show/Hide	C17H24N2O3	1
1	EC50 = 53703.18 nM Bioactivity Info	TI LI LO TS
CP0861449 Compound Info	(3S,4R)-4-(benzylamino)-3-hydroxy-2,2-dimethyl-3,4-dihydrochromene-6-carbonitrile Show/Hide	C19H20N2O2	1
1	EC50 = 58884.37 nM Bioactivity Info	TI LI LO TS
CP0888650 Compound Info	(2S,4aR,10bS)-5,5-dimethyl-3-oxo-2-propan-2-yl-1,2,4a,10b-tetrahydrochromeno[3,4-b][1,4]oxazine-9-carbonitrile Show/Hide	C17H20N2O3	1
1	EC50 = 58884.37 nM Bioactivity Info	TI LI LO TS
CP0912175 Compound Info	(4aR,10bS)-1,5,5-trimethyl-2,3,4a,10b-tetrahydrochromeno[3,4-b][1,4]oxazine-9-carbonitrile Show/Hide	C15H18N2O2	1
1	EC50 = 61659.5 nM Bioactivity Info	TI LI LO TS
CP0957069 Compound Info	1-[2-[(2R)-2-hydroxy-3-morpholin-4-ylpropoxy]phenyl]ethanone Show/Hide	C15H21NO4	1
1	EC50 = 67608.3 nM Bioactivity Info	TI LI LO TS
CP0948703 Compound Info	1-[(2R)-3-(tert-butylamino)-2-hydroxypropyl]-5-methyl-2-phenyl-4-(thiophene-2-carbonyl)pyrazol-3-one Show/Hide	C22H27N3O3S	1
1	EC50 = 72443.6 nM Bioactivity Info	TI LI LO TS
CP0931879 Compound Info	4-(benzylamino)-3-hydroxy-2,2-dimethyl-3,4-dihydrochromene-6-carbonitrile Show/Hide	C19H20N2O2	1
1	EC50 = 75857.76 nM Bioactivity Info	TI LI LO TS
CP0948707 Compound Info	(2S,4aR,10bS)-2,5,5-trimethyl-3-oxo-1,2,4a,10b-tetrahydrochromeno[3,4-b][1,4]oxazine-9-carbonitrile Show/Hide	C15H16N2O3	1
1	EC50 = 77624.71 nM Bioactivity Info	TI LI LO TS
CP0888651 Compound Info	(2R,4aS,10bR)-1,5,5-trimethyl-3-oxo-2-propan-2-yl-4a,10b-dihydro-2H-chromeno[3,4-b][1,4]oxazine-9-carbonitrile Show/Hide	C18H22N2O3	1
1	EC50 = 79432.82 nM Bioactivity Info	TI LI LO TS
CP0852467 Compound Info	4-benzoyl-1-[(2R)-3-(tert-butylamino)-2-hydroxypropyl]-5-methyl-2-phenylpyrazol-3-one Show/Hide	C24H29N3O3	1
1	EC50 = 81283.05 nM Bioactivity Info	TI LI LO TS
CP0949381 Compound Info	4-benzoyl-1-[(2R)-2-hydroxy-3-(propan-2-ylamino)propyl]-5-methyl-2-phenylpyrazol-3-one Show/Hide	C23H27N3O3	1
1	EC50 = 83176.38 nM Bioactivity Info	TI LI LO TS
CP0856356 Compound Info	1-[(2R)-2-hydroxy-3-(propylamino)propyl]-5-methyl-2-phenyl-4-(thiophene-2-carbonyl)pyrazol-3-one Show/Hide	C21H25N3O3S	1
1	EC50 = 95499.26 nM Bioactivity Info	TI LI LO TS
CP0948388 Compound Info	(3R,4S)-3-hydroxy-4-[2-hydroxyethyl(methyl)amino]-2,2-dimethyl-3,4-dihydrochromene-6-carbonitrile Show/Hide	C15H20N2O3	1
1	EC50 = 97723.72 nM Bioactivity Info	TI LI LO TS

Protein family and CMB statistics Related to the Cell Line

Cell Lines Derived from the same Tissue Source (Peripheral blood)

Cell Line Name		Organism	Disease
SET-2	Cell Line Info	Homo sapiens (Human)	Adult acute megakaryoblastic leukemia
Mono-Mac-6	Cell Line Info	Homo sapiens (Human)	Adult acute monocytic leukemia
HL-60	Cell Line Info	Homo sapiens (Human)	Adult acute myeloid leukemia
MOLM-13	Cell Line Info	Homo sapiens (Human)	Adult acute myeloid leukemia
OCI-AML-2	Cell Line Info	Homo sapiens (Human)	Adult acute myeloid leukemia
HL-60/ADR	Cell Line Info	Homo sapiens (Human)	Adult acute myeloid leukemia
MOLM-14	Cell Line Info	Homo sapiens (Human)	Adult acute myeloid leukemia
HL60/MDR	Cell Line Info	Homo sapiens (Human)	Adult acute myeloid leukemia
HL60/MRP	Cell Line Info	Homo sapiens (Human)	Adult acute myeloid leukemia
NALM-6	Cell Line Info	Homo sapiens (Human)	Adult B acute lymphoblastic leukemia
MOLT-4	Cell Line Info	Homo sapiens (Human)	Adult T acute lymphoblastic leukemia
MOLT-4/CCR5	Cell Line Info	Homo sapiens (Human)	Adult T acute lymphoblastic leukemia
Karpas-299	Cell Line Info	Homo sapiens (Human)	Anaplastic large cell lymphoma, ALK-positive
M-07e	Cell Line Info	Homo sapiens (Human)	Childhood acute megakaryoblastic leukemia
THP-1	Cell Line Info	Homo sapiens (Human)	Childhood acute monocytic leukemia
MV4-11	Cell Line Info	Homo sapiens (Human)	Childhood acute monocytic leukemia
THP1-Dual	Cell Line Info	Homo sapiens (Human)	Childhood acute monocytic leukemia
THP1-Dual KO-STING	Cell Line Info	Homo sapiens (Human)	Childhood acute monocytic leukemia
THP1-Blue ISG	Cell Line Info	Homo sapiens (Human)	Childhood acute monocytic leukemia
THP1-ASC-GFP	Cell Line Info	Homo sapiens (Human)	Childhood acute monocytic leukemia
PMNL	Cell Line Info	Homo sapiens (Human)	Childhood acute monocytic leukemia
THP1-Xblue	Cell Line Info	Homo sapiens (Human)	Childhood acute monocytic leukemia
SEM	Cell Line Info	Homo sapiens (Human)	Childhood B acute lymphoblastic leukemia
SEMK2	Cell Line Info	Homo sapiens (Human)	Childhood B acute lymphoblastic leukemia
Reh	Cell Line Info	Homo sapiens (Human)	Childhood B acute lymphoblastic leukemia
Jurkat	Cell Line Info	Homo sapiens (Human)	Childhood T acute lymphoblastic leukemia
Jurkat E6.1	Cell Line Info	Homo sapiens (Human)	Childhood T acute lymphoblastic leukemia
CCRF-CEM	Cell Line Info	Homo sapiens (Human)	Childhood T acute lymphoblastic leukemia
CCRF/VCR1000	Cell Line Info	Homo sapiens (Human)	Childhood T acute lymphoblastic leukemia
CEM/VLB100	Cell Line Info	Homo sapiens (Human)	Childhood T acute lymphoblastic leukemia
CEM/VLB500	Cell Line Info	Homo sapiens (Human)	Childhood T acute lymphoblastic leukemia
CEM-SS	Cell Line Info	Homo sapiens (Human)	Childhood T acute lymphoblastic leukemia
HPB-ALL	Cell Line Info	Homo sapiens (Human)	Childhood T acute lymphoblastic leukemia
CCRF-SB	Cell Line Info	Homo sapiens (Human)	Childhood T acute lymphoblastic leukemia
CEM-T4	Cell Line Info	Homo sapiens (Human)	Childhood T acute lymphoblastic leukemia
J-Lat 10.6	Cell Line Info	Homo sapiens (Human)	Childhood T acute lymphoblastic leukemia
12D7-MDR1	Cell Line Info	Homo sapiens (Human)	Childhood T acute lymphoblastic leukemia
FGS7 Jurkat	Cell Line Info	Homo sapiens (Human)	Childhood T acute lymphoblastic leukemia
EoL-1	Cell Line Info	Homo sapiens (Human)	Chronic eosinophilic leukemia, not otherwise specified
CII	Cell Line Info	Homo sapiens (Human)	Chronic lymphocytic leukemia
Ku812	Cell Line Info	Homo sapiens (Human)	Chronic myelogenous leukemia, BCR-ABL1 positive
Ri-1	Cell Line Info	Homo sapiens (Human)	Diffuse large B-cell lymphoma activated B-cell type
Daudi	Cell Line Info	Homo sapiens (Human)	EBV-related Burkitt lymphoma
HEL	Cell Line Info	Homo sapiens (Human)	Erythroleukemia
UKE-1	Cell Line Info	Homo sapiens (Human)	Essential thrombocythemia
L-1236	Cell Line Info	Homo sapiens (Human)	Hodgkin lymphoma
Granta-519	Cell Line Info	Homo sapiens (Human)	Mantle cell lymphoma
JeKo-1	Cell Line Info	Homo sapiens (Human)	Mantle cell lymphoma
Mino	Cell Line Info	Homo sapiens (Human)	Mantle cell lymphoma
HMC-1	Cell Line Info	Homo sapiens (Human)	Mast cell leukemia
NK-92	Cell Line Info	Homo sapiens (Human)	Natural killer cell lymphoblastic leukemia/lymphoma
NK	Cell Line Info	Homo sapiens (Human)	Natural killer cell lymphoblastic leukemia/lymphoma
KHYG-1	Cell Line Info	Homo sapiens (Human)	Natural killer cell lymphoblastic leukemia/lymphoma
RPMI-8226	Cell Line Info	Homo sapiens (Human)	Plasma cell myeloma
OPM-2	Cell Line Info	Homo sapiens (Human)	Plasma cell myeloma
U266B1	Cell Line Info	Homo sapiens (Human)	Plasma cell myeloma
KMS-18	Cell Line Info	Homo sapiens (Human)	Plasma cell myeloma
MM1.S	Cell Line Info	Homo sapiens (Human)	Plasma cell myeloma
MM1.R	Cell Line Info	Homo sapiens (Human)	Plasma cell myeloma
OPM-1	Cell Line Info	Homo sapiens (Human)	Plasma cell myeloma
RPMI-8226/Dox40	Cell Line Info	Homo sapiens (Human)	Plasma cell myeloma
HuT 78	Cell Line Info	Homo sapiens (Human)	Sezary syndrome
H9	Cell Line Info	Homo sapiens (Human)	Sezary syndrome
CREM010i-SS9-1	Cell Line Info	Homo sapiens (Human)	Sickle cell disease
RBL-1	Cell Line Info	Rattus norvegicus (Rat)	Rat leukemia
RBL-2H3	Cell Line Info	Rattus norvegicus (Rat)	Rat leukemia
LCL Orang Asli K28	Cell Line Info	Homo sapiens (Human)	-
JY	Cell Line Info	Homo sapiens (Human)	-
C.M.L.	Cell Line Info	Homo sapiens (Human)	-
BON	Cell Line Info	Homo sapiens (Human)	-
PBMC iPSC #1	Cell Line Info	Homo sapiens (Human)	-
LCL 721	Cell Line Info	Homo sapiens (Human)	-

Cite

About MolBiC

Correspondence

Prof. Feng ZHU

Prof. Leo, Lianyi Han