Brief Information of the Compound and Protein
Compound Name
(2S,4aS,10bR)-1,2,5,5-tetramethyl-3-oxo-4a,10b-dihydro-2H-chromeno[3,4-b][1,4]oxazine-9-carbonitrile
    Show/Hide
PubChem ID
CID: 73349680
Canonical SMILES
C[C@H]1C(=O)O[C@H]2[C@@H](c3cc(C#N)ccc3OC2(C)C)N1C
    Show/Hide
Compound Formula C16H18N2O3
Compound Structure
Protein Name
ATP-dependent translocase ABCB1
Protein Classification
Transporter
>
Primary active transporter
>
ATP-binding cassette
>
ABCB subfamily
Uniprot ID
P08183
Gene Name
ABCB1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL001024 MDR CCRF vcr1000 Homo sapiens (Human)  1
1
EC50 = 47863.01 nM
   TI
   LI
   LO
   TS