Brief Information of the Compound and Protein
Compound Name
[(2R,3S,4S)-3-hydroxy-4-[4-(2-methoxyphenyl)piperazin-1-yl]-2-methyl-3,4-dihydro-2H-quinolin-1-yl]-(4-methylphenyl)methanone
    Show/Hide
PubChem ID
CID: 73355771
Canonical SMILES
COc1ccccc1N1CCN([C@H]2c3ccccc3N(C(=O)c3ccc(C)cc3)[C@H](C)[C@@H]2O)CC1
    Show/Hide
Compound Formula C29H33N3O3
Compound Structure
Protein Name
ATP-dependent translocase ABCB1
Protein Classification
Transporter
>
Primary active transporter
>
ATP-binding cassette
>
ABCB subfamily
Uniprot ID
P08183
Gene Name
ABCB1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL001024 MDR CCRF vcr1000 Homo sapiens (Human)  1
1
EC50 = 3548.13 nM
   TI
   LI
   LO
   TS