Brief Information of the Compound and Protein
Compound Name
(4aR,10bS)-1,5,5-trimethyl-2,3,4a,10b-tetrahydrochromeno[3,4-b][1,4]oxazine-9-carbonitrile
    Show/Hide
PubChem ID
CID: 73351233
Canonical SMILES
CN1CCO[C@@H]2[C@@H]1c1cc(C#N)ccc1OC2(C)C
    Show/Hide
Compound Formula C15H18N2O2
Compound Structure
Protein Name
ATP-dependent translocase ABCB1
Protein Classification
Transporter
>
Primary active transporter
>
ATP-binding cassette
>
ABCB subfamily
Uniprot ID
P08183
Gene Name
ABCB1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL001024 MDR CCRF vcr1000 Homo sapiens (Human)  1
1
EC50 = 61659.5 nM
   TI
   LI
   LO
   TS