Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(2R)-2-(1,3-benzodioxol-5-yl)-3-(4-tert-butylphenyl)-1,2-dihydroquinazolin-4-one
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 PubChem ID
CID: 987245
Canonical SMILES
CC(C)(C)c1ccc(N2C(=O)c3ccccc3N[C@H]2c2ccc3c(c2)OCO3)cc1
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Compound Formula C25H24N2O3
Compound Structure
Protein Name
 Protein Info 
ATP-dependent translocase ABCB1
Protein Classification
Transporter
>
Primary active transporter
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ATP-binding cassette
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ABCB subfamily
Uniprot ID
P08183
Gene Name
ABCB1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL001024 MDR CCRF vcr1000
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 741.31 nM
   TI
   LI
   LO
   TS