Brief Information of the Compound and Protein
Compound Name
(2R)-3-[4-[(2S)-butan-2-yl]phenyl]-2-(4-propan-2-ylphenyl)-1,2-dihydroquinazolin-4-one
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PubChem ID
CID: 1723760
Canonical SMILES
CC[C@H](C)c1ccc(N2C(=O)c3ccccc3N[C@H]2c2ccc(C(C)C)cc2)cc1
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Compound Formula C27H30N2O
Compound Structure
Protein Name
ATP-dependent translocase ABCB1
Protein Classification
Transporter
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Primary active transporter
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ATP-binding cassette
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ABCB subfamily
Uniprot ID
P08183
Gene Name
ABCB1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL001024 MDR CCRF vcr1000 Homo sapiens (Human)  1
1
EC50 = 288.4 nM
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