Brief Information of the Compound and Protein
Compound Name
(4Z)-5-methyl-4-[[4-(2-methylphenyl)piperazin-1-yl]-phenylmethylidene]-2-phenylpyrazol-3-one
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PubChem ID
CID: 10646595
SID: 15678203
Canonical SMILES
CC1=NN(c2ccccc2)C(=O)/C1=C(/c1ccccc1)N1CCN(c2ccccc2C)CC1
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Compound Formula C28H28N4O
Compound Structure
Protein Name
ATP-dependent translocase ABCB1
Protein Classification
Transporter
>
Primary active transporter
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ATP-binding cassette
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ABCB subfamily
Uniprot ID
P08183
Gene Name
ABCB1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000253 CCRF/VCR1000 Homo sapiens (Human)  1
1
EC50 = 680 nM
   TI
   LI
   LO
   TS
CL001024 MDR CCRF vcr1000 Homo sapiens (Human)  1
1
EC50 = 676.08 nM
   TI
   LI
   LO
   TS