General Information of the Cell Line
Cell Line ID
CL000531
Cell Line Name
Ri-1
Synonyms
RI-1
RI1
RIVA
Riva
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_1885
Tissue Information
Peripheral blood
Disease
Diffuse large B-cell lymphoma activated B-cell type (NCIt: C36081)
Diffuse large B-cell lymphoma (ORDO: Orphanet_544)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT00999, PIK3CD
 Protein Info 
Compound ID Compound Name Compound Formula
CP0192746
 Compound Info 
2-[1-[[5-(2-ethylbenzimidazol-1-yl)-7-morpholin-4-yl-[1,3]thiazolo[4,5-d]pyrimidin-2-yl]methyl]piperidin-4-yl]propan-2-ol
   Show/Hide
C27H35N7O2S
  1
1
IC50 = 7 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0238995
 Compound Info 
2-[1-[[2-[2-(1-methoxyethyl)benzimidazol-1-yl]-9-methyl-6-morpholin-4-ylpurin-8-yl]methyl]piperidin-4-yl]propan-2-ol
   Show/Hide
C29H40N8O3
  1
1
IC50 = 10 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0339254
 Compound Info 
2-[1-[[2-(2-ethylbenzimidazol-1-yl)-6-morpholin-4-yl-7H-purin-8-yl]methyl]piperidin-4-yl]propan-2-ol
   Show/Hide
C27H36N8O2
  1
1
IC50 = 12 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0110718
 Compound Info 
2-[1-[[2-(2-ethylbenzimidazol-1-yl)-9-methyl-6-morpholin-4-ylpurin-8-yl]methyl]piperidin-4-yl]propan-2-ol
   Show/Hide
C28H38N8O2
  1
1
IC50 = 14 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0339253
 Compound Info 
2-[1-[[2-[2-(dimethylamino)benzimidazol-1-yl]-9-methyl-6-morpholin-4-ylpurin-8-yl]methyl]piperidin-4-yl]propan-2-ol
   Show/Hide
C28H39N9O2
  1
1
IC50 = 16 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0193312
 Compound Info 
2-[1-[[2-[2-(1-hydroxyethyl)benzimidazol-1-yl]-9-methyl-6-morpholin-4-ylpurin-8-yl]methyl]piperidin-4-yl]propan-2-ol
   Show/Hide
C28H38N8O3
  1
1
IC50 = 17 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0086188
 Compound Info 
2-[1-[[2-(2-cyclopropylbenzimidazol-1-yl)-9-methyl-6-morpholin-4-ylpurin-8-yl]methyl]piperidin-4-yl]propan-2-ol
   Show/Hide
C29H38N8O2
  1
1
IC50 = 19 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0148454
 Compound Info 
2-[1-[[9-methyl-6-morpholin-4-yl-2-(2-propan-2-ylbenzimidazol-1-yl)purin-8-yl]methyl]piperidin-4-yl]propan-2-ol
   Show/Hide
C29H40N8O2
  1
1
IC50 = 19 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0513993
 Compound Info 
1-[[2-(5-fluoro-1H-indol-4-yl)-4-morpholin-4-ylthieno[3,2-d]pyrimidin-6-yl]methyl]-N,N-dimethylpiperidin-4-amine
   Show/Hide
C26H31FN6OS
  1
1
IC50 = 29 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0238997
 Compound Info 
2-[1-[[5-(2-ethylbenzimidazol-1-yl)-7-morpholin-4-yl-[1,3]thiazolo[5,4-d]pyrimidin-2-yl]methyl]piperidin-4-yl]propan-2-ol
   Show/Hide
C27H35N7O2S
  1
1
IC50 = 50 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0239063
 Compound Info 
4-[2-(2-ethylbenzimidazol-1-yl)-6-[(4-methylsulfonylpiperazin-1-yl)methyl]thieno[3,2-d]pyrimidin-4-yl]morpholine
   Show/Hide
C25H31N7O3S2
  1
1
IC50 = 79 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0239062
 Compound Info 
4-[6-[[2,2-dimethyl-4-(oxetan-3-yl)piperazin-1-yl]methyl]-2-(2-ethylbenzimidazol-1-yl)thieno[3,2-d]pyrimidin-4-yl]morpholine
   Show/Hide
C29H37N7O2S
  1
1
IC50 = 102 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0169311
 Compound Info 
2-[1-[[2-(2-ethylbenzimidazol-1-yl)-4-morpholin-4-ylthieno[3,2-d]pyrimidin-6-yl]methyl]piperidin-4-yl]propan-2-ol
   Show/Hide
C28H36N6O2S
  1
1
IC50 = 116 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0193269
 Compound Info 
1-[(2-imidazo[1,2-a]pyridin-5-yl-4-morpholin-4-ylthieno[3,2-d]pyrimidin-6-yl)methyl]-N,N-dimethylpiperidin-4-amine
   Show/Hide
C25H31N7OS
  1
1
IC50 = 180 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0339241
 Compound Info 
N,N-dimethyl-1-[[2-(2-methylbenzimidazol-1-yl)-4-morpholin-4-ylthieno[3,2-d]pyrimidin-6-yl]methyl]piperidin-4-amine
   Show/Hide
C26H33N7OS
  1
1
IC50 = 374 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0169312
 Compound Info 
1-[(2-indol-1-yl-4-morpholin-4-ylthieno[3,2-d]pyrimidin-6-yl)methyl]-N,N-dimethylpiperidin-4-amine
   Show/Hide
C26H32N6OS
  1
1
IC50 = 420 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0239064
 Compound Info 
1-[[2-(benzimidazol-1-yl)-4-morpholin-4-ylthieno[3,2-d]pyrimidin-6-yl]methyl]-N,N-dimethylpiperidin-4-amine
   Show/Hide
C25H31N7OS
  1
1
IC50 = 970 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0513992
 Compound Info 
N,N-dimethyl-1-[[2-(3-methylphenyl)-4-morpholin-4-ylthieno[3,2-d]pyrimidin-6-yl]methyl]piperidin-4-amine
   Show/Hide
C25H33N5OS
  1
1
IC50 = 1300 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0247119
 Compound Info 
N,N-dimethyl-1-[[2-(3-methylisoquinolin-4-yl)-4-morpholin-4-ylthieno[3,2-d]pyrimidin-6-yl]methyl]piperidin-4-amine
   Show/Hide
C28H34N6OS
  1
1
IC50 = 2000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0186992
 Compound Info 
1-[(2-indazol-1-yl-4-morpholin-4-ylthieno[3,2-d]pyrimidin-6-yl)methyl]-N,N-dimethylpiperidin-4-amine
   Show/Hide
C25H31N7OS
  1
1
IC50 = 3200 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0239066
 Compound Info 
4-[6-[[4-(dimethylamino)piperidin-1-yl]methyl]-4-morpholin-4-ylthieno[3,2-d]pyrimidin-2-yl]-1,3-dihydroindol-2-one
   Show/Hide
C26H32N6O2S
  1
1
IC50 = 3400 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0315883
 Compound Info 
N,N-dimethyl-1-[[2-(2-methyl-1-benzothiophen-3-yl)-4-morpholin-4-ylthieno[3,2-d]pyrimidin-6-yl]methyl]piperidin-4-amine
   Show/Hide
C27H33N5OS2
  1
1
IC50 = 3800 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Peripheral blood)
Cell Line Name Organism Disease
SET-2
 Cell Line Info 
Homo sapiens (Human) Adult acute megakaryoblastic leukemia
Mono-Mac-6
 Cell Line Info 
Homo sapiens (Human) Adult acute monocytic leukemia
HL-60
 Cell Line Info 
Homo sapiens (Human) Adult acute myeloid leukemia
MOLM-13
 Cell Line Info 
Homo sapiens (Human) Adult acute myeloid leukemia
OCI-AML-2
 Cell Line Info 
Homo sapiens (Human) Adult acute myeloid leukemia
HL-60/ADR
 Cell Line Info 
Homo sapiens (Human) Adult acute myeloid leukemia
MOLM-14
 Cell Line Info 
Homo sapiens (Human) Adult acute myeloid leukemia
HL60/MDR
 Cell Line Info 
Homo sapiens (Human) Adult acute myeloid leukemia
HL60/MRP
 Cell Line Info 
Homo sapiens (Human) Adult acute myeloid leukemia
NALM-6
 Cell Line Info 
Homo sapiens (Human) Adult B acute lymphoblastic leukemia
MOLT-4
 Cell Line Info 
Homo sapiens (Human) Adult T acute lymphoblastic leukemia
MOLT-4/CCR5
 Cell Line Info 
Homo sapiens (Human) Adult T acute lymphoblastic leukemia
Karpas-299
 Cell Line Info 
Homo sapiens (Human) Anaplastic large cell lymphoma, ALK-positive
M-07e
 Cell Line Info 
Homo sapiens (Human) Childhood acute megakaryoblastic leukemia
THP-1
 Cell Line Info 
Homo sapiens (Human) Childhood acute monocytic leukemia
MV4-11
 Cell Line Info 
Homo sapiens (Human) Childhood acute monocytic leukemia
THP1-Dual
 Cell Line Info 
Homo sapiens (Human) Childhood acute monocytic leukemia
THP1-Dual KO-STING
 Cell Line Info 
Homo sapiens (Human) Childhood acute monocytic leukemia
THP1-Blue ISG
 Cell Line Info 
Homo sapiens (Human) Childhood acute monocytic leukemia
THP1-ASC-GFP
 Cell Line Info 
Homo sapiens (Human) Childhood acute monocytic leukemia
PMNL
 Cell Line Info 
Homo sapiens (Human) Childhood acute monocytic leukemia
THP1-Xblue
 Cell Line Info 
Homo sapiens (Human) Childhood acute monocytic leukemia
SEM
 Cell Line Info 
Homo sapiens (Human) Childhood B acute lymphoblastic leukemia
SEMK2
 Cell Line Info 
Homo sapiens (Human) Childhood B acute lymphoblastic leukemia
Reh
 Cell Line Info 
Homo sapiens (Human) Childhood B acute lymphoblastic leukemia
Jurkat
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
Jurkat E6.1
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
CCRF-CEM
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
CCRF/VCR1000
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
CEM/VLB100
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
CEM/VLB500
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
CEM-SS
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
HPB-ALL
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
CCRF-SB
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
CEM-T4
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
J-Lat 10.6
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
12D7-MDR1
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
MDR CCRF vcr1000
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
FGS7 Jurkat
 Cell Line Info 
Homo sapiens (Human) Childhood T acute lymphoblastic leukemia
EoL-1
 Cell Line Info 
Homo sapiens (Human) Chronic eosinophilic leukemia, not otherwise specified
CII
 Cell Line Info 
Homo sapiens (Human) Chronic lymphocytic leukemia
Ku812
 Cell Line Info 
Homo sapiens (Human) Chronic myelogenous leukemia, BCR-ABL1 positive
Daudi
 Cell Line Info 
Homo sapiens (Human) EBV-related Burkitt lymphoma
HEL
 Cell Line Info 
Homo sapiens (Human) Erythroleukemia
UKE-1
 Cell Line Info 
Homo sapiens (Human) Essential thrombocythemia
L-1236
 Cell Line Info 
Homo sapiens (Human) Hodgkin lymphoma
Granta-519
 Cell Line Info 
Homo sapiens (Human) Mantle cell lymphoma
JeKo-1
 Cell Line Info 
Homo sapiens (Human) Mantle cell lymphoma
Mino
 Cell Line Info 
Homo sapiens (Human) Mantle cell lymphoma
HMC-1
 Cell Line Info 
Homo sapiens (Human) Mast cell leukemia
NK-92
 Cell Line Info 
Homo sapiens (Human) Natural killer cell lymphoblastic leukemia/lymphoma
NK
 Cell Line Info 
Homo sapiens (Human) Natural killer cell lymphoblastic leukemia/lymphoma
KHYG-1
 Cell Line Info 
Homo sapiens (Human) Natural killer cell lymphoblastic leukemia/lymphoma
RPMI-8226
 Cell Line Info 
Homo sapiens (Human) Plasma cell myeloma
OPM-2
 Cell Line Info 
Homo sapiens (Human) Plasma cell myeloma
U266B1
 Cell Line Info 
Homo sapiens (Human) Plasma cell myeloma
KMS-18
 Cell Line Info 
Homo sapiens (Human) Plasma cell myeloma
MM1.S
 Cell Line Info 
Homo sapiens (Human) Plasma cell myeloma
MM1.R
 Cell Line Info 
Homo sapiens (Human) Plasma cell myeloma
OPM-1
 Cell Line Info 
Homo sapiens (Human) Plasma cell myeloma
RPMI-8226/Dox40
 Cell Line Info 
Homo sapiens (Human) Plasma cell myeloma
HuT 78
 Cell Line Info 
Homo sapiens (Human) Sezary syndrome
H9
 Cell Line Info 
Homo sapiens (Human) Sezary syndrome
CREM010i-SS9-1
 Cell Line Info 
Homo sapiens (Human) Sickle cell disease
RBL-1
 Cell Line Info 
Rattus norvegicus (Rat) Rat leukemia
RBL-2H3
 Cell Line Info 
Rattus norvegicus (Rat) Rat leukemia
LCL Orang Asli K28
 Cell Line Info 
Homo sapiens (Human) -
JY
 Cell Line Info 
Homo sapiens (Human) -
C.M.L.
 Cell Line Info 
Homo sapiens (Human) -
BON
 Cell Line Info 
Homo sapiens (Human) -
PBMC iPSC #1
 Cell Line Info 
Homo sapiens (Human) -
LCL 721
 Cell Line Info 
Homo sapiens (Human) -