Brief Information of the Compound and Protein
Compound Name
N1-(7-((5-(4-amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)pyridin-3-yl)methoxy)-2-cyclobutylquinolin-4-yl)-N2,N2-dimethylethane-1,2-diamine
    Show/Hide
PubChem ID
CID: 156304005
Canonical SMILES
CN(C)CCNc1cc(C2CCC2)nc2cc(OCc3cncc(-n4ccc5c(N)ncnc54)c3)ccc12
    Show/Hide
Compound Formula C29H32N8O
Compound Structure
Protein Name
N6-adenosine-methyltransferase catalytic subunit
Protein Classification
Enzyme
>
Transferase
Uniprot ID
Q86U44
Gene Name
METTL3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000071 MOLM-13 Homo sapiens (Human)  1
1
IC50 = 1000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 < 10 nM