Brief Information of the Compound and Protein
Compound Name
(2R,3R,4S,5R)-2-[4-amino-5-(1-methylpyrazol-3-yl)pyrrolo[2,3-d]pyrimidin-7-yl]-5-[[2-(methylamino)quinolin-7-yl]oxymethyl]oxolane-3,4-diol
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PubChem ID
CID: 156327795
Canonical SMILES
CNc1ccc2ccc(OC[C@H]3O[C@H]([C@H](O)[C@@H]3O)n3cc(-c4ccn(C)n4)c4c(N)ncnc34)cc2n1
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Compound Formula C25H26N8O4
Compound Structure
Protein Name
N6-adenosine-methyltransferase catalytic subunit
Protein Classification
Enzyme
>
Transferase
Uniprot ID
Q86U44
Gene Name
METTL3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000071 MOLM-13 Homo sapiens (Human)  1
1
IC50 < 1000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 < 10 nM