Brief Information of the Compound and Protein
Compound Name
(2R,3S,5R)-5-(4-amino-5-pyrazol-1-yl-pyrrolo[2,3-d]pyrimidin-7-yl)-2-[[2-(azetidin-1-yl)-7-quinolyl]oxymethyl]tetrahydrofuran-3-ol
    Show/Hide
PubChem ID
CID: 156730065
Canonical SMILES
Nc1ncnc2c1c(-n1cccn1)cn2[C@H]1C[C@H](O)[C@@H](COc2ccc3ccc(N4CCC4)nc3c2)O1
    Show/Hide
Compound Formula C26H26N8O3
Compound Structure
Protein Name
N6-adenosine-methyltransferase catalytic subunit
Protein Classification
Enzyme
>
Transferase
Uniprot ID
Q86U44
Gene Name
METTL3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000071 MOLM-13 Homo sapiens (Human)  1
1
IC50 < 1000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 < 10 nM