General Information of the Protein
Protein ID
PT06374
Protein Name
Calcium release-activated calcium channel protein 1
Secondarily
Protein Name
Protein orai-1
Transmembrane protein 142A
Gene Name
ORAI1
Secondarily
Gene Name
Cracm1
Tmem142a
Sequence
MHPEPAPPPNNSNPELPLSGGSSTSGSRRSRRRSGDGEPTGAPPLPPPPAVSYPDWIGQSYSEVMSLNEHSMQALSWRKLYLSRAKLKASSRTSALLSGFAMVAMVEVQLDTDHDYPPGLLIVFSACTTVLVAVHLFALMISTCILPNIEAVSNVHNLNSVKESPHERMHRHIELAWAFSTVIGTLLFLAEVVLLCWVKFLPLKRQAGQPSPTKPPTEPAVVVANSSNNGGITPGEAAAIASTAIMVPCGLVFIVFAVHFYRSLVSHKTDRQFQELNELAEFARLQDQLDHRGDHSLTPGTHYA
    Show/Hide
Organism
Rattus norvegicus, Rat
Protein Classification
Ion channel
>
Other ion channel
>
Miscellaneous ion channel
>
Ca2+ release-activated Ca2+ channel family
Function
Ca(2+) release-activated Ca(2+) (CRAC) channel subunit which mediates Ca(2+) influx following depletion of intracellular Ca(2+) stores and channel activation by the Ca(2+) sensor, STIM1. CRAC channels are the main pathway for Ca(2+) influx in T-cells and promote the immune response to pathogens by activating the transcription factor NFAT. Plays a prominent role in Ca(2+) influx at the basolateral membrane of mammary epithelial cells independently of the Ca(2+) content of endoplasmic reticulum or Golgi stores. May mediate transepithelial transport of large quantities of Ca(2+) for milk secretion.
    Show/Hide
Uniprot ID
Q5M848
Ensembl ID
ENSG00000276045
Subcellular Location
Cell membrane
Basolateral cell membrane
Map of Molecular Bioactivity Related to the Protein
Map of Molecular Bioactivity Related to the Protein

Protein
Cell Line
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Protein
Cell Line ID: CL000278 , RBL-2H3
 Cell Line Info 
Compound ID Compound Name Compound Formula
CP0635842
 Compound Info 
N-(2,6-difluorobenzyl)-4-fluoro-5-(1-methyl-3-(trifluoromethyl)-1H-pyrazol-5-yl)pyridin-2-amine
   Show/Hide
C17H12F6N4
  1
1
IC50 = 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0639320
 Compound Info 
5-(2,5-bis(trifluoromethyl)phenoxy)-N-(2,4,6-trifluorobenzyl)pyridin-2-amine
   Show/Hide
C20H11F9N2O
  1
1
IC50 = 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0639359
 Compound Info 
5-(2,2-difluoro-6-methylbenzo[d]1,3-dioxolen-5-yl)-2-[2,6-difluorophenyl)methoxy]pyrimidine
   Show/Hide
C19H12F4N2O3
  1
1
IC50 = 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0639458
 Compound Info 
2-(2,6-difluorobenzyloxy)-5-(1-methyl-3-(trifluoromethyl)pyrazol-5-yl)pyridine
   Show/Hide
C17H12F5N3O
  1
1
IC50 = 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0967650
 Compound Info 
N-(3-fluoro-2-methylbenzyl)-5-(2-methyl-4-(trifluoromethyl)-1H-imidazol-1-yl)pyridin-2-amine
   Show/Hide
C18H16F4N4
  1
1
IC50 = 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0633640
 Compound Info 
5-(2,5-dimethylthiazol-4-yl)-N-(2-fluorobenzyl)pyridin-2-amine
   Show/Hide
C17H16FN3S
  1
1
IC50 < 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0633671
 Compound Info 
N-(2,6-difluorobenzyl)-5-(2-(trifluoromethyl)phenoxy)pyridin-2-amine
   Show/Hide
C19H13F5N2O
  1
1
IC50 < 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0633672
 Compound Info 
N-(2-fluorobenzyl)-5-(1-methyl-3-(trifluoromethyl)-1H-pyrazol-5-yl)pyrimidin-2-amine
   Show/Hide
C16H13F4N5
  1
1
IC50 < 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0633673
 Compound Info 
5-(2,2-difluoro-6-methylbenzo[d]1,3-dioxolen-5-yl)-2-[2-chloro-6-fluorophenyl)methoxy]pyrimidine
   Show/Hide
C19H12ClF3N2O3
  1
1
IC50 < 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0633676
 Compound Info 
5-(6-chloro-2,2-difluorobenzo[d][1,3]dioxol-5-yl)-N-(3-fluorobenzyl)pyridin-2-amine
   Show/Hide
C19H12ClF3N2O2
  1
1
IC50 < 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0634218
 Compound Info 
N-(2,4,6-trifluorobenzyl)-5-(2-(trifluoromethyl)phenoxy)pyridin-2-amine
   Show/Hide
C19H12F6N2O
  1
1
IC50 < 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0634219
 Compound Info 
N-(2,6-difluoro-4-methoxybenzyl)-5-(5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)pyridin-2-amine
   Show/Hide
C18H15F5N4O
  1
1
IC50 < 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0634220
 Compound Info 
5-(2,2-difluoro-6-methylbenzo[d][1,3]dioxol-5-yl)-N-(2,4,6-trifluorobenzyl)pyridin-2-amine
   Show/Hide
C20H13F5N2O2
  1
1
IC50 < 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0634221
 Compound Info 
5-(6-chloro-2,2-difluorobenzo[d][1,3]dioxol-5-yl)-N-(2-chloro-4-fluorobenzyl)pyridin-2-amine
   Show/Hide
C19H11Cl2F3N2O2
  1
1
IC50 < 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0634222
 Compound Info 
5-(6-chloro-2,2-difluorobenzo[d][1,3]dioxol-5-yl)-N-(2-chloro-3-fluorobenzyl)pyridin-2-amine
   Show/Hide
C19H11Cl2F3N2O2
  1
1
IC50 < 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0634620
 Compound Info 
N-(2,6-difluoro-4-methoxybenzyl)-5-(2,2-difluoro-6-methylbenzo[d][1,3]dioxol-5-yl)pyrimidin-2-amine
   Show/Hide
C20H15F4N3O3
  1
1
IC50 < 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0634621
 Compound Info 
N-(2,6-difluorobenzyl)-5-(2-(trifluoromethyl)phenoxy)pyrimidin-2-amine
   Show/Hide
C18H12F5N3O
  1
1
IC50 < 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0634798
 Compound Info 
6-(1-ethyl-3-(trifluoromethyl)-1H-pyrazol-5-yl)-N-(2,4,6-trifluorobenzyl)pyridin-3-amine
   Show/Hide
C18H14F6N4
  1
1
IC50 < 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0635620
 Compound Info 
5-(6-chloro-2,2-difluorobenzo[d][1,3]dioxol-5-yl)-N-(2-chlorobenzyl)pyridin-2-amine
   Show/Hide
C19H12Cl2F2N2O2
  1
1
IC50 < 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0635621
 Compound Info 
5-(2,2-difluoro-6-methylbenzo[d][1,3]dioxol-5-yl)-N-(2,6-difluorobenzyl)pyridin-2-amine
   Show/Hide
C20H14F4N2O2
  1
1
IC50 < 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0635622
 Compound Info 
5-(6-chloro-2,2-difluorobenzo[d][1,3]dioxol-5-yl)-N-(2,6-difluorobenzyl)pyridin-2-amine
   Show/Hide
C19H11ClF4N2O2
  1
1
IC50 < 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0635654
 Compound Info 
5-(3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl)-N-(2,6-difluorobenzyl)pyridin-2-amine
   Show/Hide
C17H10F8N4
  1
1
IC50 < 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0635715
 Compound Info 
N-((3,5-difluoropyridin-4-yl)methyl)-5-(1-methyl-3-(trifluoromethyl)-1H-pyrazol-5-yl)pyridin-2-amine
   Show/Hide
C16H12F5N5
  1
1
IC50 < 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0636048
 Compound Info 
6-(1-methyl-3-(trifluoromethyl)-1H-pyrazol-5-yl)-N-(2,4,6-trifluorobenzyl)pyridin-3-amine
   Show/Hide
C17H12F6N4
  1
1
IC50 < 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0636119
 Compound Info 
5-(6-chloro-2,2-difluorobenzo[d][1,3]dioxol-5-yl)-N-(2-methoxybenzyl)pyridin-2-amine
   Show/Hide
C20H15ClF2N2O3
  1
1
IC50 < 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0636180
 Compound Info 
N-(4-chloro-2,6-difluorobenzyl)-5-(6-chloro-4-methylpyridin-3-yl)pyrimidin-2-amine
   Show/Hide
C17H12Cl2F2N4
  1
1
IC50 < 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0636968
 Compound Info 
5-(1-methyl-3-(trifluoromethyl)-1H-pyrazol-5-yl)-N-(2,3,6-trifluorobenzyl)pyridin-2-amine
   Show/Hide
C17H12F6N4
  1
1
IC50 < 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0637163
 Compound Info 
N-(2-fluoro-6-methylbenzyl)-5-(1-methyl-3-(trifluoromethyl)-1H-pyrazol-5-yl)pyridin-2-amine
   Show/Hide
C18H16F4N4
  1
1
IC50 < 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0637164
 Compound Info 
5-(2,2-difluoro-6-methyl-1,3-benzodioxol-5-yl)-N-[(2,6-difluorophenyl)methyl]pyrimidin-2-amine
   Show/Hide
C19H13F4N3O2
  1
1
IC50 < 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0637165
 Compound Info 
5-(2,5-dimethylthiazol-4-yl)-N-(2,4,6-trifluorobenzyl)pyridin-2-amine
   Show/Hide
C17H14F3N3S
  1
1
IC50 < 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0637938
 Compound Info 
N-(2-chlorobenzyl)-5-(2,2-difluoro-6-methylbenzo[d][1,3]dioxol-5-yl)pyridin-2-amine
   Show/Hide
C20H15ClF2N2O2
  1
1
IC50 < 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0637939
 Compound Info 
5-(2,5-bis(trifluoromethyl)phenoxy)-N-(2,6-difluorobenzyl)pyridin-2-amine
   Show/Hide
C20H12F8N2O
  1
1
IC50 < 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0637941
 Compound Info 
N-(2,6-difluorobenzyl)-5-(5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)pyridin-2-amine
   Show/Hide
C17H13F5N4
  1
1
IC50 < 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0637942
 Compound Info 
5-(3,5-bis(trifluoromethyl)-1H-pyrazol-1-yl)-N-(2,4,6-trifluorobenzyl)pyridin-2-amine
   Show/Hide
C17H9F9N4
  1
1
IC50 < 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0638207
 Compound Info 
N-(2,6-difluorobenzyl)-5-(7-methyl-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)pyridin-2-amine
   Show/Hide
C21H18F2N2O2
  1
1
IC50 < 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0638208
 Compound Info 
5-(2,2-difluoro-6-methylbenzo[d][1,3]dioxol-5-yl)-N-(2,3,6-trifluorobenzyl)pyridin-2-amine
   Show/Hide
C20H13F5N2O2
  1
1
IC50 < 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0638209
 Compound Info 
5-(2,2-difluoro-6-methylbenzo[d][1,3]dioxol-5-yl)-N-(2-methylbenzyl)pyridin-2-amine
   Show/Hide
C21H18F2N2O2
  1
1
IC50 < 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0638247
 Compound Info 
N-(2,6-difluorobenzyl)-5-(5-fluoro-2-(trifluoromethyl)phenoxy)pyridin-2-amine
   Show/Hide
C19H12F6N2O
  1
1
IC50 < 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0638249
 Compound Info 
N-(2,6-difluorobenzyl)-5-(6-methoxy-4-methylpyridin-3-yl)pyrimidin-2-amine
   Show/Hide
C18H16F2N4O
  1
1
IC50 < 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0638250
 Compound Info 
N-((3,5-difluoropyridin-4-yl)methyl)-5-(5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)pyridin-2-amine
   Show/Hide
C16H12F5N5
  1
1
IC50 < 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0638438
 Compound Info 
N2-(2-fluorobenzyl)-5-(1-methyl-3-(trifluoromethyl)-1H-pyrazol-5-yl)pyridine-2,6-diamine
   Show/Hide
C17H15F4N5
  1
1
IC50 < 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0638698
 Compound Info 
6-(1-ethyl-3-(trifluoromethyl)-1H-pyrazol-5-yl)-N-(2-fluorobenzyl)pyridin-3-amine
   Show/Hide
C18H16F4N4
  1
1
IC50 < 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0639027
 Compound Info 
N-(2,6-difluorobenzyl)-5-(1-methyl-3-(trifluoromethyl)-1H-pyrazol-5-yl)pyrimidin-2-amine
   Show/Hide
C16H12F5N5
  1
1
IC50 < 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0639028
 Compound Info 
N-(2,6-difluorobenzyl)-5-fluoro-6-(1-methyl-3-(trifluoromethyl)-1H-pyrazol-5-yl)pyridin-3-amine
   Show/Hide
C17H12F6N4
  1
1
IC50 < 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0639029
 Compound Info 
N-(2-fluorobenzyl)-5-(1-methyl-3-(trifluoromethyl)-1H-pyrazol-5-yl)pyridin-2-amine
   Show/Hide
C17H14F4N4
  1
1
IC50 < 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0639030
 Compound Info 
5-(7-chloro-2,3-dihydro-[1,4]dioxino[2,3-b]pyridin-6-yl)-N-(4-fluoro-2-methylbenzyl)pyridin-2-amine
   Show/Hide
C20H17ClFN3O2
  1
1
IC50 < 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0639031
 Compound Info 
5-(7-chloro-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-N-(2,6-difluorobenzyl)pyridin-2-amine
   Show/Hide
C20H15ClF2N2O2
  1
1
IC50 < 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0639032
 Compound Info 
5-(2,2-difluoro-6-methylbenzo[d][1,3]dioxol-5-yl)-N-(2,4,6-trifluorobenzyl)pyrazin-2-amine
   Show/Hide
C19H12F5N3O2
  1
1
IC50 < 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0639033
 Compound Info 
5-(2,2-difluoro-6-methylbenzo[d][1,3]dioxol-5-yl)-N-(2-fluorobenzyl)pyridin-2-amine
   Show/Hide
C20H15F3N2O2
  1
1
IC50 < 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0639034
 Compound Info 
N-(2,6-difluorobenzyl)-5-(6-methyl-2,3-dihydro-1H-inden-5-yl)pyridin-2-amine
   Show/Hide
C22H20F2N2
  1
1
IC50 < 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0639149
 Compound Info 
N-((3,5-difluoropyridin-4-yl)methyl)-5-(5-fluoro-2-(trifluoromethyl)phenoxy)pyridin-2-amine
   Show/Hide
C18H11F6N3O
  1
1
IC50 < 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0639321
 Compound Info 
N-(2,6-difluorobenzyl)-6-(1-ethyl-3-(trifluoromethyl)-1H-pyrazol-5-yl)pyridin-3-amine
   Show/Hide
C18H15F5N4
  1
1
IC50 < 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0639322
 Compound Info 
5-(1-methyl-3-(trifluoromethyl)-1H-pyrazol-5-yl)-N-(2,4-difluorobenzyl)pyridin-2-amine
   Show/Hide
C17H13F5N4
  1
1
IC50 < 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0639323
 Compound Info 
N-(2,6-difluorobenzyl)-5-(1-methyl-3-(trifluoromethyl)-1H-pyrazol-5-yl)pyridin-2-amine
   Show/Hide
C17H13F5N4
  1
1
IC50 < 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0639324
 Compound Info 
5-(2,2-difluoro-6-methylbenzo[d]1,3-dioxolen-5-yl)-2-[(2,6-difluorophenyl)methoxy]pyridine
   Show/Hide
C20H13F4NO3
  1
1
IC50 < 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0639325
 Compound Info 
5-(7-chloro-2,3-dihydro-[1,4]dioxino[2,3-b]pyridin-6-yl)-N-(2,6-difluorobenzyl)pyridin-2-amine
   Show/Hide
C19H14ClF2N3O2
  1
1
IC50 < 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0639326
 Compound Info 
N-(2-chloro-6-fluorobenzyl)-5-(2,2-difluoro-6-methylbenzo[d][1,3]dioxol-5-yl)pyridin-2-amine
   Show/Hide
C20H14ClF3N2O2
  1
1
IC50 < 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0639354
 Compound Info 
5-(5-fluoro-2-(trifluoromethyl)phenoxy)-N-(2,4,6-trifluorobenzyl)pyridin-2-amine
   Show/Hide
C19H11F7N2O
  1
1
IC50 < 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0639355
 Compound Info 
5-(5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)-N-(2,4,6-trifluorobenzyl)pyridin-2-amine
   Show/Hide
C17H12F6N4
  1
1
IC50 < 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0639356
 Compound Info 
5-(2-methyl-4-(trifluoromethyl)-1H-imidazol-1-yl)-N-(2,4,6-trifluorobenzyl)pyridin-2-amine
   Show/Hide
C17H12F6N4
  1
1
IC50 < 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0639357
 Compound Info 
N-(2,6-difluorobenzyl)-5-(2-methyl-4-(trifluoromethyl)-1H-imidazol-1-yl)pyridin-2-amine
   Show/Hide
C17H13F5N4
  1
1
IC50 < 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0639358
 Compound Info 
5-(1-methyl-3-(trifluoromethyl)-1H-pyrazol-5-yl)-N-(2,4,6-trifluorobenzyl)pyridin-2-amine
   Show/Hide
C17H12F6N4
  1
1
IC50 < 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0639360
 Compound Info 
6-(2,2-difluoro-6-methylbenzo[d][1,3]dioxol-5-yl)-N-(2,6-difluorobenzyl)pyridin-3-amine
   Show/Hide
C20H14F4N2O2
  1
1
IC50 < 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0850823
 Compound Info 
N-(3-fluoro-2-methylbenzyl)-5-(5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)pyridin-2-amine
   Show/Hide
C18H16F4N4
  1
1
IC50 < 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0862348
 Compound Info 
5-(6-chloro-2,2-difluorobenzo[d][1,3]dioxol-5-yl)-N-(2-(trifluoromethyl)benzyl)pyridin-2-amine
   Show/Hide
C20H12ClF5N2O2
  1
1
IC50 < 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0896532
 Compound Info 
N-(5-fluoro-2-methylbenzyl)-5-(6-methyl-2,3-dihydro-1H-inden-5-yl)pyridin-2-amine
   Show/Hide
C23H23FN2
  1
1
IC50 < 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0946466
 Compound Info 
5-(6-chloro-2,2-difluorobenzo[d][1,3]dioxol-5-yl)-N-(5-fluoro-2-methoxybenzyl)pyridin-2-amine
   Show/Hide
C20H14ClF3N2O3
  1
1
IC50 < 600 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0634217
 Compound Info 
5-(2-ethylphenoxy)-N-(2,4,6-trifluorobenzyl)pyridin-2-amine
   Show/Hide
C20H17F3N2O
  1
1
IC50 > 1200 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0636779
 Compound Info 
2-(2,6-difluorobenzyloxy)-5-(1-methyl-3-(trifluoromethyl)-1H-pyrazol-5-yl)pyrimidine
   Show/Hide
C16H11F5N4O
  1
1
IC50 > 1200 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0637940
 Compound Info 
N-(2,6-difluorobenzyl)-5-(2-ethylphenoxy)pyridin-2-amine
   Show/Hide
C20H18F2N2O
  1
1
IC50 > 1200 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0896533
 Compound Info 
N-((3,5-difluoropyridin-4-yl)methyl)-5-(2-methyl-4-(trifluoromethyl)-1H-imidazol-1-yl)pyridin-2-amine
   Show/Hide
C16H12F5N5
  1
1
IC50 > 1200 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Similar Protein(s) and Bioactivity Statistics
50% Identity
Protein ID Protein Name Protein Organism
PT06229 Calcium release-activated calcium channel protein 1 Homo sapiens, Human
 Protein Info