Brief Information of the Compound and Protein
Compound Name
5-(2,2-difluoro-6-methylbenzo[d]1,3-dioxolen-5-yl)-2-[2,6-difluorophenyl)methoxy]pyrimidine
    Show/Hide
PubChem ID
CID: 71105441
Canonical SMILES
Cc1cc2c(cc1-c1cnc(OCc3c(F)cccc3F)nc1)OC(F)(F)O2
    Show/Hide
Compound Formula C19H12F4N2O3
Compound Structure
Protein Name
Calcium release-activated calcium channel protein 1
Protein Classification
Ion channel
>
Other ion channel
>
Miscellaneous ion channel
>
Ca2+ release-activated Ca2+ channel family
Uniprot ID
Q5M848
Gene Name
ORAI1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000278 RBL-2H3 Rattus norvegicus (Rat)  1
1
IC50 = 600 nM
   TI
   LI
   LO
   TS