Brief Information of the Compound and Protein
Compound Name
5-(2,2-difluoro-6-methylbenzo[d][1,3]dioxol-5-yl)-N-(2,6-difluorobenzyl)pyridin-2-amine
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PubChem ID
CID: 71086602
SID: 163470276
Canonical SMILES
Cc1cc2c(cc1-c1ccc(NCc3c(F)cccc3F)nc1)OC(F)(F)O2
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Compound Formula C20H14F4N2O2
Compound Structure
Protein Name
Calcium release-activated calcium channel protein 1
Protein Classification
Ion channel
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Other ion channel
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Miscellaneous ion channel
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Ca2+ release-activated Ca2+ channel family
Uniprot ID
Q5M848
Gene Name
ORAI1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000278 RBL-2H3 Rattus norvegicus (Rat)  1
1
IC50 < 600 nM
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