1-Acyl-1H-[1,2,4]triazole-3,5-diamine Analogue 3b

1-[[(1S)-1-cyclopropylethyl]amino]-7-(1-methylpyrazol-4-yl)-5H-pyrido[4,3-b]indole-4-carboxamide

7-(2-aminopyrimidin-5-yl)-1-[[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]amino]-5H-pyrido[4,3-b]indole-4-carboxamide

1-(dicyclopropylmethylamino)-7-pyridazin-3-yl-5H-pyrido[4,3-b]indole-4-carboxamide

7-(2-aminopyrimidin-5-yl)-1-(dicyclopropylmethylamino)-5H-pyrido[4,3-b]indole-4-carboxamide

1-[[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]amino]-7-(1H-pyrazol-4-yl)-5H-pyrido[4,3-b]indole-4-carboxamide

1-(dicyclopropylmethylamino)-7-(1H-pyrazol-4-yl)-5H-pyrido[4,3-b]indole-4-carboxamide

1-[[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]amino]-7-(1-methylpyrazol-4-yl)-5H-pyrido[4,3-b]indole-4-carboxamide

1-(1-cyclopropylpropylamino)-7-(1-methylpyrazol-4-yl)-5H-pyrido[4,3-b]indole-4-carboxamide

7-(6-aminopyridin-3-yl)-1-[[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]amino]-5H-pyrido[4,3-b]indole-4-carboxamide

1-[[(1R)-1-cyclopropylethyl]amino]-7-(1-methylpyrazol-4-yl)-5H-pyrido[4,3-b]indole-4-carboxamide

1-[(1-cyclopropyl-2-methylpropyl)amino]-7-(1-methylpyrazol-4-yl)-5H-pyrido[4,3-b]indole-4-carboxamide

7-(5-aminopyrazin-2-yl)-1-(dicyclopropylmethylamino)-5H-pyrido[4,3-b]indole-4-carboxamide

1-[[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]amino]-7-[6-(1,1-dioxo-1,4-thiazinan-4-yl)pyridazin-3-yl]-5H-pyrido[4,3-b]indole-4-carboxamide

1-(dicyclopropylmethylamino)-7-(1-methylpyrazol-4-yl)-5H-pyrido[4,3-b]indole-4-carboxamide

INCB-018424

(2R)-2-amino-N-[4-[2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]phenyl]propanamide

1-[[(1R)-1-cyclobutyl-2,2,2-trifluoroethyl]amino]-7-(1-methylpyrazol-4-yl)-5H-pyrido[4,3-b]indole-4-carboxamide

4-[[(2S)-3,3-dimethylbutan-2-yl]amino]-7-(1-methylpyrazol-4-yl)-9H-carbazole-1-carboxamide

(2R)-N-[4-[2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]phenyl]pyrrolidine-2-carboxamide

N-[4-[5-methyl-2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]phenyl]acetamide

N-[3-[[4-(4-acetamidophenyl)pyrimidin-2-yl]amino]phenyl]-2,6-dichlorobenzamide

1-[[(1S)-1-cyclopropyl-2,2,2-trifluoroethyl]amino]-7-(1-methylpyrazol-4-yl)-5H-pyrido[4,3-b]indole-4-carboxamide

1-[[(1R)-1-cyclopropyl-2,2,2-trifluoroethyl]amino]-7-(2-morpholin-4-ylpyrimidin-5-yl)-5H-pyrido[4,3-b]indole-4-carboxamide

N-[4-[2-(3-morpholin-4-ylanilino)pyrimidin-4-yl]phenyl]acetamide

(2R)-2-amino-3-hydroxy-N-[4-[2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]phenyl]propanamide

(2R)-1-methyl-N-[4-[2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]phenyl]pyrrolidine-2-carboxamide

N-[4-[2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]phenyl]acetamide

N-[4-[2-(3-piperidin-1-ylanilino)pyrimidin-4-yl]phenyl]acetamide

N-[4-(2-anilinopyrimidin-4-yl)phenyl]acetamide

3-[2-[5-methyl-2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]-6,7-dihydro-4H-furo[3,2-c]pyridin-5-yl]-3-oxopropanenitrile

(2S)-2-amino-N-[4-[2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]phenyl]propanamide

5-methyl-4-(5-methylsulfonyl-6,7-dihydro-4H-furo[3,2-c]pyridin-2-yl)-N-(4-morpholin-4-ylphenyl)pyrimidin-2-amine

4-(5-methylsulfonyl-6,7-dihydro-4H-furo[3,2-c]pyridin-2-yl)-N-[4-(2-pyrrolidin-1-ylethoxy)phenyl]pyrimidin-2-amine

3-[2-[2-(3,5-difluoro-4-morpholin-4-ylanilino)-5-methylpyrimidin-4-yl]-6,7-dihydro-4H-furo[3,2-c]pyridin-5-yl]-3-oxopropanenitrile

3-[2-[5-methyl-2-(3,4,5-trimethoxyanilino)pyrimidin-4-yl]-6,7-dihydro-4H-furo[3,2-c]pyridin-5-yl]-3-oxopropanenitrile

(2R)-1-ethyl-N-[4-[2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]phenyl]pyrrolidine-2-carboxamide

N-(3,5-difluoro-4-morpholin-4-ylphenyl)-5-methyl-4-(5-methylsulfonyl-6,7-dihydro-4H-furo[3,2-c]pyridin-2-yl)pyrimidin-2-amine

N-[4-[2-(4-morpholin-4-ylanilino)-5-(trifluoromethyl)pyrimidin-4-yl]phenyl]acetamide

2-[5-methyl-2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]-1-benzofuran-5-carbonitrile

3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)piperidin-1-yl)-3-oxopropanenitrile

3-[2-[2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]-6,7-dihydro-4H-furo[3,2-c]pyridin-5-yl]-3-oxopropanenitrile

N-[4-[5-fluoro-2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]phenyl]acetamide

3-[2-[2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]-6,7-dihydro-4H-furo[3,2-c]pyridin-5-yl]-3-oxopropanenitrile

N-[3-[[4-(4-acetamidophenyl)pyrimidin-2-yl]amino]propyl]-2,6-dichlorobenzamide

5-methyl-4-(5-methylsulfonyl-6,7-dihydro-4H-furo[3,2-c]pyridin-2-yl)-N-phenylpyrimidin-2-amine

N-[6-[[4-(4-acetamidophenyl)pyrimidin-2-yl]amino]pyridin-2-yl]-2,6-dichlorobenzamide

N-[4-[6-(4-morpholin-4-ylanilino)pyrimidin-4-yl]phenyl]acetamide

N-[4-[2-[[1-(2,6-dichlorobenzoyl)azetidin-3-yl]methylamino]pyrimidin-4-yl]phenyl]acetamide

N-[4-[6-methyl-2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]phenyl]acetamide

N-[3-[[4-(4-acetamidophenyl)pyrimidin-2-yl]amino]phenyl]benzamide

(3S)-N-[4-[2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]phenyl]pyrrolidine-3-carboxamide

(2R)-N-[4-[2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]phenyl]-5-oxopyrrolidine-2-carboxamide

N-[3-[[4-(4-acetamidophenyl)pyrimidin-2-yl]amino]cyclohexyl]-2,6-dichlorobenzamide

N-[3-[[4-(4-acetamidophenyl)pyrimidin-2-yl]amino]phenyl]-2-chlorobenzamide