Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(2R)-2-amino-N-[4-[2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]phenyl]propanamide
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 PubChem ID
CID: 57991398
Canonical SMILES
C[C@@H](N)C(=O)Nc1ccc(cc1)-c1ccnc(Nc2ccc(cc2)N2CCOCC2)n1
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Compound Formula C23H26N6O2
Compound Structure
Protein Name
 Protein Info 
Tyrosine-protein kinase JAK2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase JakB family
Uniprot ID
O60674
Gene Name
JAK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000082 HEL
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 327.7 nM
   TI
   LI
   LO
   TS
2
IC50 = 452 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1.7 nM