Brief Information of the Compound and Protein
Compound Name
2-[5-methyl-2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]-1-benzofuran-5-carbonitrile
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PubChem ID
CID: 134150297
Canonical SMILES
Cc1cnc(Nc2ccc(cc2)N2CCOCC2)nc1-c1cc2cc(ccc2o1)C#N
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Compound Formula C24H21N5O2
Compound Structure
Protein Name
Tyrosine-protein kinase JAK2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase JakB family
Uniprot ID
O60674
Gene Name
JAK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000082 HEL Homo sapiens (Human)  1
1
IC50 = 3088 nM
   TI
   LI
   LO
   TS
CL000128 TF-1 Homo sapiens (Human)  1
1
IC50 = 1052 nM
   TI
   LI
   LO
   TS