Brief Information of the Compound and Protein
Compound Name
7-(2-aminopyrimidin-5-yl)-1-(dicyclopropylmethylamino)-5H-pyrido[4,3-b]indole-4-carboxamide
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PubChem ID
CID: 42635901
SID: 81074946
Canonical SMILES
NC(=O)c1cnc(NC(C2CC2)C2CC2)c2c3ccc(cc3[nH]c12)-c1cnc(N)nc1
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Compound Formula C23H23N7O
Compound Structure
Protein Name
Tyrosine-protein kinase JAK2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase JakB family
Uniprot ID
O60674
Gene Name
JAK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000082 HEL Homo sapiens (Human)  1
1
IC50 = 29 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1 nM