Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-[[(2S)-3,3-dimethylbutan-2-yl]amino]-7-(1-methylpyrazol-4-yl)-9H-carbazole-1-carboxamide
    Show/Hide
 PubChem ID
CID: 56683053
Canonical SMILES
C[C@H](Nc1ccc(C(N)=O)c2[nH]c3cc(ccc3c12)-c1cnn(C)c1)C(C)(C)C
    Show/Hide
Compound Formula C23H27N5O
Compound Structure
Protein Name
 Protein Info 
Tyrosine-protein kinase JAK2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase JakB family
Uniprot ID
O60674
Gene Name
JAK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000082 HEL
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 370 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 5 nM