Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[4-[5-methyl-2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]phenyl]acetamide
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 PubChem ID
CID: 24877791
SID: 50133181
Canonical SMILES
CC(=O)Nc1ccc(cc1)-c1nc(Nc2ccc(cc2)N2CCOCC2)ncc1C
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Compound Formula C23H25N5O2
Compound Structure
Protein Name
 Protein Info 
Tyrosine-protein kinase JAK2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase JakB family
Uniprot ID
O60674
Gene Name
JAK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000082 HEL
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 447 nM
   TI
   LI
   LO
   TS
2
IC50 = 608.9 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 5.1 nM
2 IC50 = 28.7 nM