Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-(dicyclopropylmethylamino)-7-pyridazin-3-yl-5H-pyrido[4,3-b]indole-4-carboxamide
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 PubChem ID
CID: 42636016
SID: 81075064
Canonical SMILES
NC(=O)c1cnc(NC(C2CC2)C2CC2)c2c3ccc(cc3[nH]c12)-c1cccnn1
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Compound Formula C23H22N6O
Compound Structure
Protein Name
 Protein Info 
Tyrosine-protein kinase JAK2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase JakB family
Uniprot ID
O60674
Gene Name
JAK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000082 HEL
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 28 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 2 nM