Brief Information of the Compound and Protein
Compound Name
N-[4-(2-anilinopyrimidin-4-yl)phenyl]acetamide
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PubChem ID
CID: 69023801
Canonical SMILES
CC(=O)Nc1ccc(cc1)-c1ccnc(Nc2ccccc2)n1
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Compound Formula C18H16N4O
Compound Structure
Protein Name
Tyrosine-protein kinase JAK2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase JakB family
Uniprot ID
O60674
Gene Name
JAK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000082 HEL Homo sapiens (Human)  2
1
IC50 = 1004.3 nM
   TI
   LI
   LO
   TS
2
IC50 = 1971 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 12.8 nM
2 IC50 = 27.4 nM