Brief Information of the Compound and Protein
Compound Name
N-[4-[2-(3-piperidin-1-ylanilino)pyrimidin-4-yl]phenyl]acetamide
    Show/Hide
PubChem ID
CID: 24877440
SID: 50132835
Canonical SMILES
CC(=O)Nc1ccc(cc1)-c1ccnc(Nc2cccc(c2)N2CCCCC2)n1
    Show/Hide
Compound Formula C23H25N5O
Compound Structure
Protein Name
Tyrosine-protein kinase JAK2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase JakB family
Uniprot ID
O60674
Gene Name
JAK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000082 HEL Homo sapiens (Human)  2
1
IC50 = 956.1 nM
   TI
   LI
   LO
   TS
2
IC50 = 1328 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 6.5 nM
2 IC50 = 13.8 nM