| Compound ID |
Compound Name |
Compound Formula |
|
CP0378763
|
5-({4-[(3S)-4-(5-Bromo-2,3-dihydro-1H-inden-1-yl)-3-methylpiperazin-1-yl]-4-methylpiperidin-1-yl}carbonyl)-4,6-dimethylpyrimidine
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|
C27H36BrN5O
|
1
|
| 1 |
IC50 = 1.1 nM
|
|
|
|
CP0317835
|
(4,6-Dimethyl-pyrimidin-5-yl)-(4-{(S)-4-[(R)-2-methoxy-1-(4-trifluoromethyl-phenyl)-ethyl]-3-methyl-piperazin-1-yl}-4-methyl-piperidin-1-yl)-methanone
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|
C28H38F3N5O2
|
1
|
| 1 |
IC50 = 1.2 nM
|
|
|
|
CP0465684
|
4,6-Dimethyl-5-[(4-methyl-4-{(3S)-3-methyl-4-[5-(trifluoromethyl)-2,3-dihydro-1H-inden-1-yl]piperazin-1-yl}piperidin-1-yl)carbonyl]pyrimidine
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|
C28H36F3N5O
|
1
|
| 1 |
IC50 = 1.2 nM
|
|
|
|
CP0180768
|
5-[(4-(3S)-4-[(1R,2R)-2-ethoxy-5-(trifluoromethyl)-2,3-dihydro-1H-inden-1-yl]-3-methylpiperazin-1-yl-4-methylpiperidin-1-yl)carbonyl]-4,6-dimethylpyrimidine
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|
C30H40F3N5O2
|
2
|
| 1 |
IC50 = 3 nM
|
|
|
| 2 |
Kd = 3.1 nM
|
|
|
|
CP0503934
|
5-[(4-(3S)-4-[(1R,2R)-2-methoxy-5-(trifluoromethyl)-2,3-dihydro-1H-inden-1-yl]-3-methylpiperazin-1-yl-4-methylpiperidin-1-yl)carbonyl]-4,6-dimethylpyrimidine
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|
C29H38F3N5O2
|
1
|
| 1 |
IC50 = 3.5 nM
|
|
|
|
CP0681545
|
1-(6-((2-(Dimethylamino)ethyl)(methyl)amino)-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridine-5-carbonyl)-3-(3-isopropoxyphenyl)urea Hydrochloride
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|
C24H34ClN7O3
|
2
|
| 1 |
IC50 = 400 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
|
CP0378480
|
1-(1,3-Dimethyl-1H-pyrazolo[3,4-b]pyridine-5-carbonyl)-3-(4-fluoro-3-(trifluoromethyl)phenyl)urea
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|
C17H13F4N5O2
|
2
|
| 1 |
IC50 = 2900 nM
|
|
|
| 2 |
IC50 > 10000 nM
|
|
|
