Brief Information of the Compound and Protein
Compound Name
(3S,5S)-7-cyclohexyl-1-ethyl-3-hydroxy-1,7-diazaspiro[4.4]nonan-6-one
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PubChem ID
CID: 168294109
Canonical SMILES
CCN1C[C@@H](O)C[C@]11CCN(C2CCCCC2)C1=O
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Compound Formula C15H26N2O2
Compound Structure
Protein Name
11-beta-hydroxysteroid dehydrogenase 1
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P28845
Gene Name
HSD11B1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000752 PBMC iPSC #1 Homo sapiens (Human)  1
1
IC50 = 21 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 15 nM