| Compound ID |
Compound Name |
Compound Formula |
|
CP0296536
|
(2R)-2-[(2S)-4-[5-fluoro-3-(hydroxymethyl)-6-(2H-pyrazolo[3,4-b]pyridin-3-yl)pyridin-2-yl]piperazin-2-yl]-3-methylbutan-2-ol
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|
C21H27FN6O2
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0155925
|
(2R)-2-[(2S)-4-[3,5-difluoro-6-(2H-pyrazolo[3,4-b]pyridin-3-yl)pyridin-2-yl]piperazin-2-yl]-3-methylbutan-2-ol
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|
C20H24F2N6O
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0115289
|
5-fluoro-2-[(3S)-3-[(2R)-2-hydroxy-3-methylbutan-2-yl]piperazin-1-yl]-6-(2H-pyrazolo[3,4-b]pyridin-3-yl)pyridin-3-ol
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|
C20H25FN6O2
|
1
|
| 1 |
IC50 = 4 nM
|
|
|
|
CP0301373
|
(2R)-2-[(2S)-4-[5-fluoro-6-(2H-pyrazolo[3,4-b]pyridin-3-yl)pyridin-2-yl]piperazin-2-yl]-3-methylbutan-2-ol
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|
C20H25FN6O
|
1
|
| 1 |
IC50 = 6 nM
|
|
|
|
CP0115546
|
(2R)-2-[(2S)-4-[3-chloro-5-fluoro-6-(2H-pyrazolo[3,4-b]pyridin-3-yl)pyridin-2-yl]piperazin-2-yl]-3-methylbutan-2-ol
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|
C20H24ClFN6O
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
|
CP0246631
|
5-fluoro-2-[(3S)-3-[(2R)-2-hydroxy-3-methylbutan-2-yl]piperazin-1-yl]-6-(2H-pyrazolo[3,4-b]pyridin-3-yl)pyridine-3-carbonitrile
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|
C21H24FN7O
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0246626
|
(2R)-2-[(2S)-4-[5-chloro-6-(2H-pyrazolo[3,4-b]pyridin-3-yl)pyridin-2-yl]piperazin-2-yl]-3-methylbutan-2-ol
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|
C20H25ClN6O
|
1
|
| 1 |
IC50 = 170 nM
|
|
|
|
CP0203505
|
(2R)-3-methyl-2-[(2S)-4-[6-(2H-pyrazolo[3,4-b]pyridin-3-yl)-5-(trifluoromethyl)pyridin-2-yl]piperazin-2-yl]butan-2-ol
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|
C21H25F3N6O
|
1
|
| 1 |
IC50 = 420 nM
|
|
|
