Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-[4-[[(3R,5S)-7-cyclohexyl-3-hydroxy-6-oxo-1,7-diazaspiro[4.4]nonan-1-yl]methyl]phenyl]-N-methylpyridine-2-carboxamide
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 PubChem ID
CID: 168282373
Canonical SMILES
CNC(=O)c1ccc(cn1)-c1ccc(CN2C[C@H](O)C[C@]22CCN(C3CCCCC3)C2=O)cc1
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Compound Formula C27H34N4O3
Compound Structure
Protein Name
 Protein Info 
11-beta-hydroxysteroid dehydrogenase 1
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P28845
Gene Name
HSD11B1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000752 PBMC iPSC #1
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 7.2 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 3 nM