Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-methyl-4-[5-[1-[(1R)-3-oxospiro[2-benzofuran-1,3'-pyrrolidine]-1'-carbonyl]cyclopropyl]pyridin-2-yl]benzamide
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 PubChem ID
CID: 66661933
Canonical SMILES
CNC(=O)c1ccc(cc1)-c1ccc(cn1)C1(CC1)C(=O)N1CC[C@@]2(C1)OC(=O)c1ccccc21
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Compound Formula C28H25N3O4
Compound Structure
Protein Name
 Protein Info 
11-beta-hydroxysteroid dehydrogenase 1
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P28845
Gene Name
HSD11B1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000752 PBMC iPSC #1
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 21 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 16 nM