Protein Information

General Information of the Protein

Protein ID	PT00004
Protein Name	Pol polyprotein
Gene Name	POL
Sequence	PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF Show/Hide
Organism	Human immunodeficiency virus 1
Protein Classification	Enzyme > Protease > Aspartic protease > Aspartic protease AA clan > Aspartic protease A2A subfamily
Uniprot ID	Q72874

Map of Molecular Bioactivity Related to the Protein

Map of Molecular Bioactivity Related to the Protein Protein Cell Line Compound Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity

Table of Molecular Bioactivities Related to the Protein

Cell Line ID: CL000108 , CCRF-CEM

Cell Line Info

Compound ID	Compound Name	Compound Formula
CP0122475 Compound Info	methyl (2S)-3-methyl-2-[[(2S,3S)-3-methyl-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoyl]amino]propanoyl]amino]-3-phenylpropanoyl]-prop-2-enylamino]propanoyl]amino]pentanoyl]amino]butanoate Show/Hide	C38H60N6O9	1
1	IC50 = 3892.983233 nM Bioactivity Info	TI LI LO TS
CP0296159 Compound Info	methyl (2S)-3-methyl-2-[[(2S,3S)-3-methyl-2-[[(2S)-2-[[(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoyl]-prop-2-enylamino]propanoyl]amino]pentanoyl]amino]butanoate Show/Hide	C32H50N4O7	1
1	IC50 > 16590.07582 nM Bioactivity Info	TI LI LO TS
CP0182290 Compound Info	methyl (2S)-2-[[(2S,3S)-2-[[2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-3-hydroxy-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoyl]amino]propanoyl]amino]propanoyl]amino]-3-phenylpropanoyl]-prop-2-enylamino]acetyl]amino]-3-methylpentanoyl]amino]-3-methylbutanoate Show/Hide	C40H63N7O11	1
1	IC50 > 24450.47556 nM Bioactivity Info	TI LI LO TS
CP0217312 Compound Info	methyl (2S)-2-[[(2S,3S)-2-[[2-[2,3-dichloropropyl-[(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoyl]amino]acetyl]amino]-3-methylpentanoyl]amino]-3-methylbutanoate Show/Hide	C31H48Cl2N4O7	1
1	IC50 > 50481.31585 nM Bioactivity Info	TI LI LO TS
CP0046266 Compound Info	methyl (2S)-3-methyl-2-[[(2S,3S)-3-methyl-2-[[2-[[(2S)-2-[[(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]propanoyl]amino]-3-phenylpropanoyl]-prop-2-enylamino]acetyl]amino]pentanoyl]amino]butanoate Show/Hide	C34H53N5O8	1
1	IC50 = 54104.84519 nM Bioactivity Info	TI LI LO TS
CP0105952 Compound Info	methyl (2S)-2-[[(2S,3S)-2-[[2-[2,3-dibromopropyl-[(2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoyl]amino]acetyl]amino]-3-methylpentanoyl]amino]-3-methylbutanoate Show/Hide	C31H48Br2N4O7	1
1	IC50 = 56789.7936 nM Bioactivity Info	TI LI LO TS

Cell Line ID: CL000407 , CEM-SS

Cell Line Info

Cell Line ID: CL000394 , H9

Cell Line Info

Cell Line ID: CL000262 , MT-2

Cell Line Info

Cell Line ID: CL000247 , MT-4

Cell Line Info

Cell Line ID: CL000752 , PBMC iPSC #1

Cell Line Info

Biochemical Assays

Compound ID	Compound Name	Compound Formula
CP0040838 Compound Info	(2S)-1-[(2S,4R)-4-benzyl-2-hydroxy-4-{[(1S,2R)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]carbamoyl}butyl]-N-tert-butyl-4-(pyridin-3-ylmethyl)piperazine-2-carboxamide Show/Hide	C36H47N5O4	29
1	IC50 = 0.36 nM
2	IC50 = 0.41 nM
3	IC50 = 0.56 nM
4	IC50 = 0.59 nM
5	IC50 = 0.6 nM
6	IC50 = 1.6 nM
7	IC50 = 20.1 nM
8	IC50 = 35.3 nM
9	IC50 = 43.6 nM
10	IC50 = 61 nM
11	IC50 = 61.2 nM
12	IC50 = 89 nM
13	IC50 = 370 nM
14	Kd = 1.07 nM
15	Ki = 0.07 nM
16	Ki = 0.24 nM
17	Ki = 0.28 nM
18	Ki = 0.31 nM
19	Ki = 0.37 nM
20	Ki = 0.52 nM
21	Ki = 0.6 nM
22	Ki = 0.8 nM
23	Ki = 1.34 nM
24	Ki = 2.51 nM
25	Ki = 7 nM
26	Ki = 10.4 nM
27	Ki = 15 nM
28	Ki = 40 nM
29	Ki = 50 nM
CP0038005 Compound Info	(3S)-oxolan-3-yl N-[(2S,3R)-4-[(4-aminobenzene)(2-methylpropyl)sulfonamido]-3-hydroxy-1-phenylbutan-2-yl]carbamate Show/Hide	C25H35N3O6S	15
1	IC50 = 1 nM
2	Kd = 1.1 nM
3	Ki = 0.04 nM
4	Ki = 0.057 nM
5	Ki = 0.08 nM
6	Ki < 0.1 nM
7	Ki = 0.1 nM
8	Ki = 0.15 nM
9	Ki = 0.16 nM
10	Ki = 0.17 nM
11	Ki = 0.21 nM
12	Ki = 0.23 nM
13	Ki = 0.6 nM
14	Ki = 1.4 nM
15	Ki = 1.6 nM
CP0306936 Compound Info	4-Hydroxy-3-(2-isopropyl-phenylsulfanyl)-6-m-tolyl-pyran-2-one Show/Hide	C21H20O3S	1
1	IC50 = 14 nM
CP0041607 Compound Info	(AZT) 1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione Show/Hide	C10H13N5O4	2
1	IC50 = 16 nM
2	IC50 = 23 nM
CP0113693 Compound Info	Aptivus Show/Hide	C31H33F3N2O5S	2
1	IC50 = 30 nM
2	Ki < 1 nM
CP0811023 Compound Info	5-Cyano-pyridine-2-sulfonic acid {3-[1-((R)-4-hydroxy-2-oxo-6-phenethyl-6-propyl-5,6-dihydro-2H-pyran-3-yl)-propyl]-phenyl}-amide Show/Hide	C31H33N3O5S	1
1	IC50 = 40 nM
CP0685123 Compound Info	5-Cyano-pyridine-2-sulfonic acid {3-[1-((R)-4-hydroxy-2-oxo-6-phenethyl-6-propyl-5,6-dihydro-2H-pyran-3-yl)-propyl]-phenyl}-amide Show/Hide	C31H33N3O5S	3
1	IC50 = 110 nM
2	Ki = 0.04 nM
3	Ki = 0.1 nM
CP0685136 Compound Info	5-Cyano-pyridine-2-sulfonic acid {3-[1-((S)-4-hydroxy-2-oxo-6-phenethyl-6-propyl-5,6-dihydro-2H-pyran-3-yl)-propyl]-phenyl}-amide Show/Hide	C31H33N3O5S	3
1	IC50 = 490 nM
2	Ki = 0.04 nM
3	Ki = 0.1 nM
CP0713224 Compound Info	1-Methyl-1H-imidazole-4-sulfonic acid {3-[1-(4-hydroxy-2-oxo-6-phenethyl-6-propyl-5,6-dihydro-2H-pyran-3-yl)-propyl]-phenyl}-amide Show/Hide	C29H35N3O5S	3
1	IC50 = 500 nM
2	Ki = 1 nM
3	Ki = 1.2 nM
CP0658725 Compound Info	Quinoline-8-sulfonic acid {3-[1-(4-hydroxy-2-oxo-6-phenethyl-6-propyl-5,6-dihydro-2H-pyran-3-yl)-propyl]-phenyl}-amide Show/Hide	C34H36N2O5S	3
1	IC50 = 1000 nM
2	Ki = 3 nM
3	Ki = 3.1 nM
CP0674852 Compound Info	4-Cyano-N-{3-[1-(4-hydroxy-2-oxo-6-phenethyl-6-propyl-5,6-dihydro-2H-pyran-3-yl)-propyl]-phenyl}-benzenesulfonamide Show/Hide	C32H34N2O5S	3
1	IC50 = 1100 nM
2	Ki = 8 nM
3	Ki = 8.2 nM
CP0661213 Compound Info	4-Fluoro-N-{3-[1-(4-hydroxy-2-oxo-6-phenethyl-6-propyl-5,6-dihydro-2H-pyran-3-yl)-propyl]-phenyl}-benzenesulfonamide Show/Hide	C31H34FNO5S	3
1	IC50 = 1200 nM
2	Ki = 6 nM
3	Ki = 6.1 nM
CP0661103 Compound Info	N-{3-[1-(4-Hydroxy-2-oxo-6-phenethyl-6-propyl-5,6-dihydro-2H-pyran-3-yl)-propyl]-phenyl}-benzenesulfonamide Show/Hide	C31H35NO5S	2
1	IC50 = 1600 nM
2	Ki = 17 nM
CP0328607 Compound Info	2-Butanol deriv. 17 Show/Hide	C34H40N2O3	1
1	IC50 = 11500 nM
CP0371571 Compound Info	2-Butanol deriv. 16 Show/Hide	C30H38N2O3	1
1	IC50 = 63000 nM
CP0714228 Compound Info	5-Cyano-pyridine-2-sulfonic acid {3-[1-((S)-4-hydroxy-2-oxo-6-phenethyl-6-propyl-5,6-dihydro-2H-pyran-3-yl)-propyl]-phenyl}-amide Show/Hide	C31H33N3O5S	2
1	IC50 > 1000 nM
2	Ki = 0.12 nM
CP0086074 Compound Info	Atazanavir Show/Hide	C38H52N6O7	2
1	Kd = 0.4 nM
2	Ki = 0.24 nM
CP0670346 Compound Info	5-Trifluoromethyl-pyridine-2-sulfonic acid {3-[1-((S)-4-hydroxy-2-oxo-6-phenethyl-6-propyl-5,6-dihydro-2H-pyran-3-yl)-propyl]-phenyl}-amide Show/Hide	C31H33F3N2O5S	1
1	Ki = 0.018 nM
CP0370605 Compound Info	(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl N-[(2S,3R)-4-[(4-aminobenzene)(cyclohexyloxy)sulfonamido]-3-hydroxy-1-phenylbutan-2-yl]carbamate Show/Hide	C29H39N3O8S	1
1	Ki = 0.018 nM
CP0808342 Compound Info	1-Methyl-1H-imidazole-4-sulfonic acid {3-[1-((R)-4-hydroxy-2-oxo-6-phenethyl-6-propyl-5,6-dihydro-2H-pyran-3-yl)-propyl]-phenyl}-amide Show/Hide	C29H35N3O5S	1
1	Ki = 0.06 nM
CP0310135 Compound Info	N-alkoxysulfonamide analog 9 Show/Hide	C30H43N3O8S	1
1	Ki = 0.09 nM
CP0692315 Compound Info	5-Cyano-pyridine-2-sulfonic acid {3-[1-(4-hydroxy-2-oxo-6-phenethyl-6-propyl-5,6-dihydro-2H-pyran-3-yl)-propyl]-phenyl}-amide Show/Hide	C31H33N3O5S	1
1	Ki = 0.1 nM
CP0788411 Compound Info	1-Methyl-1H-imidazole-4-sulfonic acid {3-[1-((S)-4-hydroxy-2-oxo-6-phenethyl-6-propyl-5,6-dihydro-2H-pyran-3-yl)-propyl]-phenyl}-amide Show/Hide	C29H35N3O5S	1
1	Ki = 0.12 nM
CP0706790 Compound Info	{(1S,2R)-3-[Cyclopentyloxy-(4-methoxy-benzenesulfonyl)-amino]-2-hydroxy-1-phenyl-propyl}-carbamic acid tetrahydro-furan-3-yl ester Show/Hide	C27H36N2O8S	1
1	Ki = 0.19 nM
CP0670345 Compound Info	5-Amino-pyridine-2-sulfonic acid {3-[1-(4-hydroxy-2-oxo-6-phenethyl-6-propyl-5,6-dihydro-2H-pyran-3-yl)-2,2-dimethyl-propyl]-phenyl}-amide Show/Hide	C32H39N3O5S	1
1	Ki = 0.2 nM
CP0771905 Compound Info	1-Methyl-1H-imidazole-4-sulfonic acid {3-[1-((R)-4-hydroxy-2-oxo-6-phenethyl-6-propyl-5,6-dihydro-2H-pyran-3-yl)-propyl]-phenyl}-amide Show/Hide	C29H35N3O5S	1
1	Ki = 0.3 nM
CP0812076 Compound Info	1-Methyl-1H-imidazole-4-sulfonic acid {3-[cyclopropyl-(4-hydroxy-2-oxo-6,6-dipropyl-5,6-dihydro-2H-pyran-3-yl)-methyl]-phenyl}-amide Show/Hide	C25H33N3O5S	1
1	Ki = 0.52 nM
CP0095253 Compound Info	2-Benzyl-5-(10-sec-butyl-9,12-dioxo-2-oxa-8,11-diaza-bicyclo[13.2.2]nonadeca-1(18),15(19),16-trien-13-ylamino)-4-hydroxy-pentanoic acid (2-hydroxy-indan-1-yl)-amide Show/Hide	C41H54N4O6	1
1	Ki = 0.6 nM
CP0801491 Compound Info	1-Methyl-1H-imidazole-4-sulfonic acid {3-[cyclopropyl-(4-hydroxy-2-oxo-6-phenethyl-6-propyl-5,6-dihydro-2H-pyran-3-yl)-methyl]-phenyl}-amide Show/Hide	C30H35N3O5S	1
1	Ki = 0.71 nM
CP0147413 Compound Info	4-hydroxy-3-(1-phenylpropyl)-2H-chromen-2-one Show/Hide	C18H16O3	2
1	Ki = 0.8 nM
2	Ki = 1000 nM
CP0648742 Compound Info	1-Methyl-1H-imidazole-4-sulfonic acid {3-[1-(4-hydroxy-2-oxo-6,6-dipropyl-5,6-dihydro-2H-pyran-3-yl)-2,2-dimethyl-propyl]-phenyl}-amide Show/Hide	C26H37N3O5S	1
1	Ki = 0.87 nM
CP0683500 Compound Info	1-Methyl-1H-imidazole-4-sulfonic acid {3-[1-(4-hydroxy-2-oxo-6,6-diphenethyl-5,6-dihydro-2H-pyran-3-yl)-propyl]-phenyl}-amide Show/Hide	C34H37N3O5S	1
1	Ki = 1 nM
CP0713211 Compound Info	1-Methyl-1H-imidazole-4-sulfonic acid {3-[1-((S)-4-hydroxy-2-oxo-6-phenethyl-6-propyl-5,6-dihydro-2H-pyran-3-yl)-propyl]-phenyl}-amide Show/Hide	C29H35N3O5S	1
1	Ki = 1 nM
CP0771894 Compound Info	1-Methyl-1H-imidazole-4-sulfonic acid {3-[1-(4-hydroxy-2-oxo-6-phenethyl-6-propyl-5,6-dihydro-2H-pyran-3-yl)-2,2-dimethyl-propyl]-phenyl}-amide Show/Hide	C31H39N3O5S	1
1	Ki = 1.2 nM
CP0659942 Compound Info	1-Methyl-1H-imidazole-4-sulfonic acid (3-{1-[6,6-bis-(2-cyclopropyl-ethyl)-4-hydroxy-2-oxo-5,6-dihydro-2H-pyran-3-yl]-propyl}-phenyl)-amide Show/Hide	C28H37N3O5S	1
1	Ki = 1.7 nM
CP0098725 Compound Info	(10S,13S,1'R)-13-[1'-HYDROXY-2'-(N-P-AMINOBENZENESULFONYL-1''-AMINO-3''-METHYLBUTYL)ETHYL]-8,11-DIOXO-10-ISOPROPYL-2-OXA-9,12-DIAZABICYCLO [13.2.2]NONADECA-15,17,18-TRIENE Show/Hide	C32H48N4O6S	1
1	Ki = 1.7 nM
CP0724374 Compound Info	1-Methyl-1H-imidazole-4-sulfonic acid {3-[1-(4-hydroxy-2-oxo-6,6-dipropyl-5,6-dihydro-2H-pyran-3-yl)-propyl]-phenyl}-amide Show/Hide	C24H33N3O5S	1
1	Ki = 1.8 nM
CP0722620 Compound Info	5-Cyano-pyridine-2-sulfonic acid {3-[1-(4-hydroxy-2-oxo-6-phenethyl-6-propyl-5,6-dihydro-2H-pyran-3-yl)-2,2-dimethyl-propyl]-phenyl}-amide Show/Hide	C33H37N3O5S	1
1	Ki = 1.9 nM
CP0720021 Compound Info	5-Nitro-pyridine-2-sulfonic acid {3-[1-(4-hydroxy-2-oxo-6-phenethyl-6-propyl-5,6-dihydro-2H-pyran-3-yl)-2,2-dimethyl-propyl]-phenyl}-amide Show/Hide	C32H37N3O7S	1
1	Ki = 2.3 nM
CP0826059 Compound Info	1-Methyl-1H-imidazole-4-sulfonic acid {3-[1-(4-hydroxy-2-oxo-6,6-dipentyl-5,6-dihydro-2H-pyran-3-yl)-propyl]-phenyl}-amide Show/Hide	C28H41N3O5S	1
1	Ki = 2.6 nM
CP0212933 Compound Info	tert-butyl N-[(2S)-1-[3-[cyclopropyl-(4-hydroxy-2-oxo-5,6,7,8,9,10-hexahydrocycloocta[b]pyran-3-yl)methyl]anilino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]carbamate Show/Hide	C32H40N4O6	1
1	Ki = 3 nM
CP0724036 Compound Info	1-Methyl-1H-imidazole-4-sulfonic acid [3-(1-{6-[2-(4-fluoro-phenyl)-ethyl]-4-hydroxy-2-oxo-6-propyl-5,6-dihydro-2H-pyran-3-yl}-propyl)-phenyl]-amide Show/Hide	C29H34FN3O5S	1
1	Ki = 3 nM
CP0785301 Compound Info	1-Methyl-1H-imidazole-4-sulfonic acid {3-[1-(4-hydroxy-6,6-diisobutyl-2-oxo-5,6-dihydro-2H-pyran-3-yl)-propyl]-phenyl}-amide Show/Hide	C26H37N3O5S	1
1	Ki = 3 nM
CP0078416 Compound Info	2-Aminobenzyl-Substituted AHPPA deriv. 1 Show/Hide	C45H55N7O7	1
1	Ki = 3.4 nM
CP0309996 Compound Info	(2-{3-[Cyclopropyl-(4-hydroxy-2-oxo-5,6,7,8,9,10-hexahydro-2H-cycloocta[b]pyran-3-yl)-methyl]-phenylcarbamoyl}-ethyl)-carbamic acid tert-butyl ester Show/Hide	C29H38N2O6	1
1	Ki = 4 nM
CP0680926 Compound Info	5-Trifluoromethyl-pyridine-2-sulfonic acid {3-[1-(4-hydroxy-2-oxo-6-phenethyl-6-propyl-5,6-dihydro-2H-pyran-3-yl)-2,2-dimethyl-propyl]-phenyl}-amide Show/Hide	C33H37F3N2O5S	1
1	Ki = 4.3 nM
CP0288634 Compound Info	({3-[Cyclopropyl-(4-hydroxy-2-oxo-5,6,7,8,9,10-hexahydro-2H-cycloocta[b]pyran-3-yl)-methyl]-phenylcarbamoyl}-methyl)-carbamic acid tert-butyl ester Show/Hide	C28H36N2O6	1
1	Ki = 5.5 nM
CP0178456 Compound Info	((S)-1-{3-[Cyclopropyl-(4-hydroxy-2-oxo-5,6,7,8,9,10-hexahydro-2H-cycloocta[b]pyran-3-yl)-methyl]-phenylcarbamoyl}-ethyl)-carbamic acid tert-butyl ester Show/Hide	C29H38N2O6	1
1	Ki = 6.9 nM
CP0740732 Compound Info	3-(Cyclopropyl-phenyl-methyl)-2,5,6,7,8,9,10,11-octahydro-cyclonona[b]pyran-4-ol Show/Hide	C22H28O2	1
1	Ki = 11.7 nM
CP0654420 Compound Info	4-Cyano-N-{3-[1-(4-hydroxy-2-oxo-6-phenethyl-6-propyl-5,6-dihydro-2H-pyran-3-yl)-2,2-dimethyl-propyl]-phenyl}-benzenesulfonamide Show/Hide	C34H38N2O5S	1
1	Ki = 12 nM
CP0114373 Compound Info	(3-{3-[Cyclopropyl-(4-hydroxy-2-oxo-5,6,7,8,9,10-hexahydro-2H-cycloocta[b]pyran-3-yl)-methyl]-phenylcarbamoyl}-propyl)-carbamic acid tert-butyl ester Show/Hide	C30H40N2O6	1
1	Ki = 14 nM
CP0189615 Compound Info	((R)-1-{3-[Cyclopropyl-(4-hydroxy-2-oxo-5,6,7,8,9,10-hexahydro-2H-cycloocta[b]pyran-3-yl)-methyl]-phenylcarbamoyl}-ethyl)-carbamic acid tert-butyl ester Show/Hide	C29H38N2O6	1
1	Ki = 32 nM
CP0806241 Compound Info	N-{3-[Cyclopropyl-(4-hydroxy-2-oxo-5,6,7,8,9,10-hexahydro-2H-cycloocta[b]pyran-3-yl)-methyl]-phenyl}-2-phenyl-acetamide Show/Hide	C29H31NO4	1
1	Ki = 33 nM
CP0777024 Compound Info	4-Hydroxy-6-phenethyl-3-(1-phenyl-propyl)-6-propyl-5,6-dihydro-pyran-2-one Show/Hide	C25H30O3	1
1	Ki = 35 nM
CP0748757 Compound Info	N-{3-[Cyclopropyl-(4-hydroxy-2-oxo-5,6,7,8,9,10-hexahydro-2H-cycloocta[b]pyran-3-yl)-methyl]-phenyl}-benzamide Show/Hide	C28H29NO4	1
1	Ki = 42 nM
CP0045716 Compound Info	(S)-2-{3-[Cyclopropyl-(4-hydroxy-2-oxo-5,6,7,8,9,10-hexahydro-2H-cycloocta[b]pyran-3-yl)-methyl]-phenylcarbamoyl}-pyrrolidine-1-carboxylic acid tert-butyl ester Show/Hide	C31H40N2O6	1
1	Ki = 43 nM
CP0726144 Compound Info	N-{3-[Cyclopropyl-(4-hydroxy-2-oxo-5,6,7,8,9,10-hexahydro-2H-cycloocta[b]pyran-3-yl)-methyl]-phenyl}-4-fluoro-benzamide Show/Hide	C28H28FNO4	1
1	Ki = 55 nM
CP0178506 Compound Info	1-{3-[Cyclopropyl-(4-hydroxy-2-oxo-5,6,7,8,9,10-hexahydro-2H-cycloocta[b]pyran-3-yl)-methyl]-phenyl}-3-ethyl-urea Show/Hide	C24H30N2O4	1
1	Ki = 72 nM
CP0045712 Compound Info	N-[3-[cyclopropyl-(4-hydroxy-2-oxo-5,6,7,8,9,10-hexahydrocycloocta[b]pyran-3-yl)methyl]phenyl]butanamide Show/Hide	C25H31NO4	1
1	Ki = 240 nM
CP0657801 Compound Info	1-{3-[Cyclopropyl-(4-hydroxy-2-oxo-5,6,7,8,9,10-hexahydro-2H-cycloocta[b]pyran-3-yl)-methyl]-phenyl}-3-phenyl-urea Show/Hide	C28H30N2O4	1
1	Ki = 450 nM
CP0671238 Compound Info	(E)-N-{3-[Cyclopropyl-(4-hydroxy-2-oxo-5,6,7,8,9,10-hexahydro-2H-cycloocta[b]pyran-3-yl)-methyl]-phenyl}-3-phenyl-acrylamide Show/Hide	C30H31NO4	1
1	Ki = 470 nM
CP0269149 Compound Info	2-Butanol deriv. 8 Show/Hide	C26H36N2O3	1
1	Ki = 20000 nM

Similar Protein(s) and Bioactivity Statistics

100% Identity

Protein ID	Protein Name	Protein Organism
PT03623	Gag-Pol polyprotein	Human immunodeficiency virus type 1 group M subtype B (isolate HXB2), HIV-1	Protein Info

Cite

About MolBiC

Correspondence

Prof. Feng ZHU

Prof. Leo, Lianyi Han