Cell Line Information

General Information of the Cell Line

Cell Line ID	CL000262
Cell Line Name	MT-2
Synonyms	MT2 MT-2J MT-2Org
Category	Transformed cell line
Organism	Homo sapiens (Human)
Cellosaurus ID	CVCL_2631
Tissue Information	Umbilical cord blood
Disease	None

Map of Molecular Bioactivity Related to the Cell Line

Map of Molecular Bioactivity Related to the Cell Line Cell Line Protein Compound Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity

Table of Molecular Bioactivities Related to the Cell Line

Protein ID: PT03623, Gag-Pol polyprotein

Protein Info

Compound ID	Compound Name	Compound Formula
CP0470674 Compound Info	4-[(1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-3a-[[2-[bis(2-hydroxyethyl)amino]ethylamino]methyl]-5a,5b,8,8,11a-pentamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,11,11b,12,13,13a,13b-tetradecahydrocyclopenta[a]chrysen-9-yl]benzoic acid Show/Hide	C43H66N2O4	2
1	EC50 = 0.34 nM Bioactivity Info	TI LI LO TS
2	IC50 = 1 nM Bioactivity Info	TI LI LO TS
CP0405454 Compound Info	4-[(1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-5a,5b,8,8,11a-pentamethyl-3a-[[3-(2-oxopyrrolidin-1-yl)propylamino]methyl]-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,11,11b,12,13,13a,13b-tetradecahydrocyclopenta[a]chrysen-9-yl]benzoic acid Show/Hide	C44H64N2O3	3
1	EC50 = 0.68 nM Bioactivity Info	TI LI LO TS
2	EC50 = 2 nM Bioactivity Info	TI LI LO TS
3	IC50 = 1.7 nM Bioactivity Info	TI LI LO TS
CP0470659 Compound Info	4-[(1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-3a-[[2-(1,1-dioxo-1,4-thiazinan-4-yl)ethylamino]methyl]-5a,5b,8,8,11a-pentamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,11,11b,12,13,13a,13b-tetradecahydrocyclopenta[a]chrysen-9-yl]benzoic acid Show/Hide	C43H64N2O4S	2
1	EC50 = 0.7 nM Bioactivity Info	TI LI LO TS
2	IC50 = 1.3 nM Bioactivity Info	TI LI LO TS
CP0513629 Compound Info	4-[(1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-5a,5b,8,8,11a-pentamethyl-3a-[[3-(4-methylpiperazin-1-yl)propylamino]methyl]-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,11,11b,12,13,13a,13b-tetradecahydrocyclopenta[a]chrysen-9-yl]benzoic acid Show/Hide	C45H69N3O2	2
1	EC50 = 0.7 nM Bioactivity Info	TI LI LO TS
2	IC50 = 0.4 nM Bioactivity Info	TI LI LO TS
CP0472851 Compound Info	4-[(1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-5a,5b,8,8,11a-pentamethyl-3a-[[[2-(methylamino)acetyl]amino]methyl]-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,11,11b,12,13,13a,13b-tetradecahydrocyclopenta[a]chrysen-9-yl]benzoic acid Show/Hide	C40H58N2O3	3
1	EC50 = 0.78 nM Bioactivity Info	TI LI LO TS
2	EC50 = 3.8 nM Bioactivity Info	TI LI LO TS
3	IC50 = 8.8 nM Bioactivity Info	TI LI LO TS
CP0393926 Compound Info	4-[(1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-3a-[[3-(1,1-dioxo-1,4-thiazinan-4-yl)propylamino]methyl]-5a,5b,8,8,11a-pentamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,11,11b,12,13,13a,13b-tetradecahydrocyclopenta[a]chrysen-9-yl]benzoic acid Show/Hide	C44H66N2O4S	8
1	EC50 = 0.94 nM Bioactivity Info	TI LI LO TS
2	EC50 = 1 nM Bioactivity Info	TI LI LO TS
3	EC50 = 1.7 nM Bioactivity Info	TI LI LO TS
4	EC50 = 2 nM Bioactivity Info	TI LI LO TS
5	EC50 = 7 nM Bioactivity Info	TI LI LO TS
6	EC50 = 15 nM Bioactivity Info	TI LI LO TS
7	EC50 > 4000 nM Bioactivity Info	TI LI LO TS
8	IC50 = 2.5 nM Bioactivity Info	TI LI LO TS
CP0394384 Compound Info	4-[(1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-5a,5b,8,8,11a-pentamethyl-1-prop-1-en-2-yl-3a-[[2-(4-sulfamoylphenyl)ethylamino]methyl]-1,2,3,4,5,6,7,7a,11,11b,12,13,13a,13b-tetradecahydrocyclopenta[a]chrysen-9-yl]benzoic acid Show/Hide	C45H62N2O4S	2
1	EC50 = 1.4 nM Bioactivity Info	TI LI LO TS
2	IC50 = 3.4 nM Bioactivity Info	TI LI LO TS
CP0547758 Compound Info	4-[(1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-5a,5b,8,8,11a-pentamethyl-3a-[(3-piperidin-1-ylpropylamino)methyl]-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,11,11b,12,13,13a,13b-tetradecahydrocyclopenta[a]chrysen-9-yl]benzoic acid Show/Hide	C45H68N2O2	2
1	EC50 = 1.4 nM Bioactivity Info	TI LI LO TS
2	IC50 = 2.4 nM Bioactivity Info	TI LI LO TS
CP0472850 Compound Info	4-[(1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-5a,5b,8,8,11a-pentamethyl-3a-[(2-morpholin-4-ylethylamino)methyl]-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,11,11b,12,13,13a,13b-tetradecahydrocyclopenta[a]chrysen-9-yl]benzoic acid Show/Hide	C43H64N2O3	2
1	EC50 = 1.5 nM Bioactivity Info	TI LI LO TS
2	IC50 = 2 nM Bioactivity Info	TI LI LO TS
CP0470671 Compound Info	4-[(1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-3a-[(2-acetamidoethylamino)methyl]-5a,5b,8,8,11a-pentamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,11,11b,12,13,13a,13b-tetradecahydrocyclopenta[a]chrysen-9-yl]benzoic acid Show/Hide	C41H60N2O3	3
1	EC50 = 1.7 nM Bioactivity Info	TI LI LO TS
2	EC50 = 4.2 nM Bioactivity Info	TI LI LO TS
3	IC50 = 3.6 nM Bioactivity Info	TI LI LO TS
CP0394383 Compound Info	4-[(1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-3a-[[3-(1,1-dioxo-1,4-thiazinan-4-yl)propyl-methylamino]methyl]-5a,5b,8,8,11a-pentamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,11,11b,12,13,13a,13b-tetradecahydrocyclopenta[a]chrysen-9-yl]benzoic acid Show/Hide	C45H68N2O4S	2
1	EC50 = 2 nM Bioactivity Info	TI LI LO TS
2	IC50 = 6 nM Bioactivity Info	TI LI LO TS
CP0472853 Compound Info	4-[(1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-3a-[[cyclopropyl-[3-(1,1-dioxo-1,4-thiazinan-4-yl)propyl]amino]methyl]-5a,5b,8,8,11a-pentamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,11,11b,12,13,13a,13b-tetradecahydrocyclopenta[a]chrysen-9-yl]benzoic acid Show/Hide	C47H70N2O4S	2
1	EC50 = 2 nM Bioactivity Info	TI LI LO TS
2	IC50 = 5 nM Bioactivity Info	TI LI LO TS
CP0566677 Compound Info	4-[(1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-3a-[(3-aminopropylamino)methyl]-5a,5b,8,8,11a-pentamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,11,11b,12,13,13a,13b-tetradecahydrocyclopenta[a]chrysen-9-yl]benzoic acid Show/Hide	C40H60N2O2	2
1	EC50 = 2 nM Bioactivity Info	TI LI LO TS
2	IC50 = 3.6 nM Bioactivity Info	TI LI LO TS
CP0489812 Compound Info	4-[(1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-3a-[[2-(dimethylamino)ethylamino]methyl]-5a,5b,8,8,11a-pentamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,11,11b,12,13,13a,13b-tetradecahydrocyclopenta[a]chrysen-9-yl]benzoic acid Show/Hide	C41H62N2O2	3
1	EC50 = 2.2 nM Bioactivity Info	TI LI LO TS
2	EC50 = 8.7 nM Bioactivity Info	TI LI LO TS
3	IC50 = 2.5 nM Bioactivity Info	TI LI LO TS
CP0470673 Compound Info	4-[(1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-3a-[2-(dimethylamino)ethylcarbamoyl]-5a,5b,8,8,11a-pentamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,11,11b,12,13,13a,13b-tetradecahydrocyclopenta[a]chrysen-9-yl]benzoic acid Show/Hide	C41H60N2O3	6
1	EC50 = 2.3 nM Bioactivity Info	TI LI LO TS
2	EC50 = 3 nM Bioactivity Info	TI LI LO TS
3	EC50 = 11 nM Bioactivity Info	TI LI LO TS
4	EC50 = 23 nM Bioactivity Info	TI LI LO TS
5	EC50 = 42 nM Bioactivity Info	TI LI LO TS
6	IC50 = 7.8 nM Bioactivity Info	TI LI LO TS
CP0411287 Compound Info	4-[(1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-3a-[(2-imidazol-1-ylethylamino)methyl]-5a,5b,8,8,11a-pentamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,11,11b,12,13,13a,13b-tetradecahydrocyclopenta[a]chrysen-9-yl]benzoic acid Show/Hide	C42H59N3O2	3
1	EC50 = 2.5 nM Bioactivity Info	TI LI LO TS
2	EC50 = 3.2 nM Bioactivity Info	TI LI LO TS
3	IC50 = 4 nM Bioactivity Info	TI LI LO TS
CP0476661 Compound Info	4-[(1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-3a-[[3-(2-hydroxyethylamino)propylamino]methyl]-5a,5b,8,8,11a-pentamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,11,11b,12,13,13a,13b-tetradecahydrocyclopenta[a]chrysen-9-yl]benzoic acid Show/Hide	C42H64N2O3	2
1	EC50 = 2.7 nM Bioactivity Info	TI LI LO TS
2	IC50 = 6.7 nM Bioactivity Info	TI LI LO TS
CP0485161 Compound Info	4-[(1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-3a-[(3-hydroxypropylamino)methyl]-5a,5b,8,8,11a-pentamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,11,11b,12,13,13a,13b-tetradecahydrocyclopenta[a]chrysen-9-yl]benzoic acid Show/Hide	C40H59NO3	2
1	EC50 = 2.7 nM Bioactivity Info	TI LI LO TS
2	IC50 = 13 nM Bioactivity Info	TI LI LO TS
CP0405455 Compound Info	4-[(1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-5a,5b,8,8,11a-pentamethyl-3a-[(3-morpholin-4-ylpropylamino)methyl]-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,11,11b,12,13,13a,13b-tetradecahydrocyclopenta[a]chrysen-9-yl]benzoic acid Show/Hide	C44H66N2O3	3
1	EC50 = 2.8 nM Bioactivity Info	TI LI LO TS
2	EC50 = 8.2 nM Bioactivity Info	TI LI LO TS
3	IC50 = 3.8 nM Bioactivity Info	TI LI LO TS
CP0526356 Compound Info	4-[(1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-3a-[[2-(2-hydroxyethylamino)ethylamino]methyl]-5a,5b,8,8,11a-pentamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,11,11b,12,13,13a,13b-tetradecahydrocyclopenta[a]chrysen-9-yl]benzoic acid Show/Hide	C41H62N2O3	2
1	EC50 = 3.3 nM Bioactivity Info	TI LI LO TS
2	IC50 = 0.42 nM Bioactivity Info	TI LI LO TS
CP0470658 Compound Info	4-[(1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-3a-[[2-(diethylamino)ethylamino]methyl]-5a,5b,8,8,11a-pentamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,11,11b,12,13,13a,13b-tetradecahydrocyclopenta[a]chrysen-9-yl]benzoic acid Show/Hide	C43H66N2O2	2
1	EC50 = 4.3 nM Bioactivity Info	TI LI LO TS
2	IC50 = 1.6 nM Bioactivity Info	TI LI LO TS
CP0470662 Compound Info	4-[(1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-5a,5b,8,8,11a-pentamethyl-3a-[[3-(N-methylanilino)propylamino]methyl]-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,11,11b,12,13,13a,13b-tetradecahydrocyclopenta[a]chrysen-9-yl]benzoic acid Show/Hide	C47H66N2O2	2
1	EC50 = 4.7 nM Bioactivity Info	TI LI LO TS
2	IC50 = 2.9 nM Bioactivity Info	TI LI LO TS
CP0411286 Compound Info	4-[(1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-5a,5b,8,8,11a-pentamethyl-3a-[(2-piperazin-1-ylethylamino)methyl]-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,11,11b,12,13,13a,13b-tetradecahydrocyclopenta[a]chrysen-9-yl]benzoic acid Show/Hide	C43H65N3O2	3
1	EC50 = 5 nM Bioactivity Info	TI LI LO TS
2	EC50 = 26 nM Bioactivity Info	TI LI LO TS
3	IC50 = 44 nM Bioactivity Info	TI LI LO TS
CP0472852 Compound Info	4-[(1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-3a-[[2-(4,4-difluoropiperidin-1-yl)ethylamino]methyl]-5a,5b,8,8,11a-pentamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,11,11b,12,13,13a,13b-tetradecahydrocyclopenta[a]chrysen-9-yl]benzoic acid Show/Hide	C44H64F2N2O2	2
1	EC50 = 6 nM Bioactivity Info	TI LI LO TS
2	IC50 = 11 nM Bioactivity Info	TI LI LO TS
CP0476662 Compound Info	4-[(1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-3a-[[2-[di(propan-2-yl)amino]ethylamino]methyl]-5a,5b,8,8,11a-pentamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,11,11b,12,13,13a,13b-tetradecahydrocyclopenta[a]chrysen-9-yl]benzoic acid Show/Hide	C45H70N2O2	2
1	EC50 = 6.7 nM Bioactivity Info	TI LI LO TS
2	IC50 = 4.4 nM Bioactivity Info	TI LI LO TS
CP0518045 Compound Info	4-[(1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-5a,5b,8,8,11a-pentamethyl-3a-[[2-(4-methylpiperazin-1-yl)ethylamino]methyl]-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,11,11b,12,13,13a,13b-tetradecahydrocyclopenta[a]chrysen-9-yl]benzoic acid Show/Hide	C44H67N3O2	3
1	EC50 = 7.7 nM Bioactivity Info	TI LI LO TS
2	EC50 = 23 nM Bioactivity Info	TI LI LO TS
3	IC50 = 29 nM Bioactivity Info	TI LI LO TS
CP0518044 Compound Info	4-[(1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-5a,5b,8,8,11a-pentamethyl-1-prop-1-en-2-yl-3a-[(2-pyridin-2-ylethylamino)methyl]-1,2,3,4,5,6,7,7a,11,11b,12,13,13a,13b-tetradecahydrocyclopenta[a]chrysen-9-yl]benzoic acid Show/Hide	C44H60N2O2	3
1	EC50 = 8 nM Bioactivity Info	TI LI LO TS
2	EC50 = 16 nM Bioactivity Info	TI LI LO TS
3	IC50 = 19 nM Bioactivity Info	TI LI LO TS
CP0275785 Compound Info	2,2-Dimethyl-succinic acid 4-((1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-3a-carboxy-1-isopropenyl-5a,5b,8,8,11a-pentamethyl-icosahydro-cyclopenta[a]chrysen-9-yl) ester Show/Hide	C36H56O6	6
1	EC50 = 10 nM Bioactivity Info	TI LI LO TS
2	EC50 = 10.4 nM Bioactivity Info	TI LI LO TS
3	EC50 = 74 nM Bioactivity Info	TI LI LO TS
4	EC50 = 970 nM Bioactivity Info	TI LI LO TS
5	EC50 = 1120 nM Bioactivity Info	TI LI LO TS
6	IC50 = 552 nM Bioactivity Info	TI LI LO TS
CP0518047 Compound Info	4-[(1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-3a-[[3-carboxypropanoyl-[2-(dimethylamino)ethyl]amino]methyl]-5a,5b,8,8,11a-pentamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,11,11b,12,13,13a,13b-tetradecahydrocyclopenta[a]chrysen-9-yl]benzoic acid Show/Hide	C45H66N2O5	3
1	EC50 = 14 nM Bioactivity Info	TI LI LO TS
2	EC50 = 21 nM Bioactivity Info	TI LI LO TS
3	IC50 = 62 nM Bioactivity Info	TI LI LO TS
CP0405456 Compound Info	(1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-9-(4-carboxyphenyl)-5a,5b,8,8,11a-pentamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,11,11b,12,13,13a,13b-tetradecahydrocyclopenta[a]chrysene-3a-carboxylic acid Show/Hide	C37H50O4	3
1	EC50 = 16 nM Bioactivity Info	TI LI LO TS
2	EC50 = 150 nM Bioactivity Info	TI LI LO TS
3	IC50 = 233 nM Bioactivity Info	TI LI LO TS
CP0394381 Compound Info	4-[(1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-3a-[[3-(dimethylamino)propylamino]methyl]-5a,5b,8,8,11a-pentamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,11,11b,12,13,13a,13b-tetradecahydrocyclopenta[a]chrysen-9-yl]benzoic acid Show/Hide	C42H64N2O2	3
1	EC50 = 27 nM Bioactivity Info	TI LI LO TS
2	EC50 = 160 nM Bioactivity Info	TI LI LO TS
3	IC50 = 79 nM Bioactivity Info	TI LI LO TS
CP0470657 Compound Info	4-[(1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-5a,5b,8,8,11a-pentamethyl-3a-[(2-piperidin-1-ylethylamino)methyl]-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,11,11b,12,13,13a,13b-tetradecahydrocyclopenta[a]chrysen-9-yl]benzoic acid Show/Hide	C44H66N2O2	3
1	EC50 = 51 nM Bioactivity Info	TI LI LO TS
2	EC50 = 210 nM Bioactivity Info	TI LI LO TS
3	IC50 = 390 nM Bioactivity Info	TI LI LO TS

Protein ID: PT00004, Pol polyprotein

Protein Info

Protein ID: PT00005, Reverse transcriptase/RNaseH

Protein Info

Protein ID: PT03634, Transmembrane protease serine 6

Protein Info

Cell Viability or Cytotoxicity Assay

Compound ID	Compound Name	Compound Formula
CP0041607 Compound Info	(AZT) 1-(4-Azido-5-hydroxymethyl-tetrahydro-furan-2-yl)-5-methyl-1H-pyrimidine-2,4-dione Show/Hide	C10H13N5O4	1
1	CC50 > 200000 nM	TI LI LO TS
CP0377875 Compound Info	[(2R,5R)-5-(6-aminopurin-9-yl)-4-fluoro-2,5-dihydrofuran-2-yl]oxymethylphosphonic acid Show/Hide	C10H11FN5O5P	1
1	CC50 > 1000000 nM	TI LI LO TS
CP0394383 Compound Info	4-[(1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-3a-[[3-(1,1-dioxo-1,4-thiazinan-4-yl)propyl-methylamino]methyl]-5a,5b,8,8,11a-pentamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,11,11b,12,13,13a,13b-tetradecahydrocyclopenta[a]chrysen-9-yl]benzoic acid Show/Hide	C45H68N2O4S	1
1	CC50 = 10000 nM	TI LI LO TS
CP0405455 Compound Info	4-[(1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-5a,5b,8,8,11a-pentamethyl-3a-[(3-morpholin-4-ylpropylamino)methyl]-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,11,11b,12,13,13a,13b-tetradecahydrocyclopenta[a]chrysen-9-yl]benzoic acid Show/Hide	C44H66N2O3	1
1	CC50 = 2200 nM	TI LI LO TS
CP0417263 Compound Info	N'-[4-[(3S,6S,9S,12S,15S,20S,23S,26S,29S,32S)-20-[[(2S)-1-amino-5-carbamimidamido-1-oxopentan-2-yl]carbamoyl]-15-[[(2S)-2-[[(2S)-5-carbamimidamido-2-[[(2S)-5-carbamimidamido-2-[(4-fluorobenzoyl)amino]pentanoyl]amino]pentanoyl]amino]-3-naphthalen-2-ylpropanoyl]amino]-6,26-bis(3-carbamimidamidopropyl)-9,23-bis[3-(carbamoylamino)propyl]-12,29-bis[(4-hydroxyphenyl)methyl]-2,5,8,11,14,22,25,28,31-nonaoxo-17,18-dithia-1,4,7,10,13,21,24,27,30-nonazabicyclo[30.3.0]pentatriacontan-3-yl]butyl]-N-[8-[4-[[2-(4-chloroanilino)-2-oxoacetyl]amino]piperidin-1-yl]octyl]butanediamide Show/Hide	C122H179ClFN39O23S2	1
1	CC50 = 8600 nM	TI LI LO TS
CP0470657 Compound Info	4-[(1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-5a,5b,8,8,11a-pentamethyl-3a-[(2-piperidin-1-ylethylamino)methyl]-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,11,11b,12,13,13a,13b-tetradecahydrocyclopenta[a]chrysen-9-yl]benzoic acid Show/Hide	C44H66N2O2	1
1	CC50 = 4000 nM	TI LI LO TS
CP0470658 Compound Info	4-[(1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-3a-[[2-(diethylamino)ethylamino]methyl]-5a,5b,8,8,11a-pentamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,11,11b,12,13,13a,13b-tetradecahydrocyclopenta[a]chrysen-9-yl]benzoic acid Show/Hide	C43H66N2O2	1
1	CC50 = 20000 nM	TI LI LO TS
CP0470659 Compound Info	4-[(1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-3a-[[2-(1,1-dioxo-1,4-thiazinan-4-yl)ethylamino]methyl]-5a,5b,8,8,11a-pentamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,11,11b,12,13,13a,13b-tetradecahydrocyclopenta[a]chrysen-9-yl]benzoic acid Show/Hide	C43H64N2O4S	1
1	CC50 = 2600 nM	TI LI LO TS
CP0470662 Compound Info	4-[(1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-5a,5b,8,8,11a-pentamethyl-3a-[[3-(N-methylanilino)propylamino]methyl]-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,11,11b,12,13,13a,13b-tetradecahydrocyclopenta[a]chrysen-9-yl]benzoic acid Show/Hide	C47H66N2O2	1
1	CC50 = 11000 nM	TI LI LO TS
CP0470674 Compound Info	4-[(1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-3a-[[2-[bis(2-hydroxyethyl)amino]ethylamino]methyl]-5a,5b,8,8,11a-pentamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,11,11b,12,13,13a,13b-tetradecahydrocyclopenta[a]chrysen-9-yl]benzoic acid Show/Hide	C43H66N2O4	1
1	CC50 = 6800 nM	TI LI LO TS
CP0472850 Compound Info	4-[(1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-5a,5b,8,8,11a-pentamethyl-3a-[(2-morpholin-4-ylethylamino)methyl]-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,11,11b,12,13,13a,13b-tetradecahydrocyclopenta[a]chrysen-9-yl]benzoic acid Show/Hide	C43H64N2O3	1
1	CC50 = 5000 nM	TI LI LO TS
CP0472851 Compound Info	4-[(1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-5a,5b,8,8,11a-pentamethyl-3a-[[[2-(methylamino)acetyl]amino]methyl]-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,11,11b,12,13,13a,13b-tetradecahydrocyclopenta[a]chrysen-9-yl]benzoic acid Show/Hide	C40H58N2O3	1
1	CC50 = 16000 nM	TI LI LO TS
CP0472852 Compound Info	4-[(1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-3a-[[2-(4,4-difluoropiperidin-1-yl)ethylamino]methyl]-5a,5b,8,8,11a-pentamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,11,11b,12,13,13a,13b-tetradecahydrocyclopenta[a]chrysen-9-yl]benzoic acid Show/Hide	C44H64F2N2O2	1
1	CC50 = 8500 nM	TI LI LO TS
CP0472853 Compound Info	4-[(1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-3a-[[cyclopropyl-[3-(1,1-dioxo-1,4-thiazinan-4-yl)propyl]amino]methyl]-5a,5b,8,8,11a-pentamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,11,11b,12,13,13a,13b-tetradecahydrocyclopenta[a]chrysen-9-yl]benzoic acid Show/Hide	C47H70N2O4S	1
1	CC50 = 7000 nM	TI LI LO TS
CP0476662 Compound Info	4-[(1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-3a-[[2-[di(propan-2-yl)amino]ethylamino]methyl]-5a,5b,8,8,11a-pentamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,11,11b,12,13,13a,13b-tetradecahydrocyclopenta[a]chrysen-9-yl]benzoic acid Show/Hide	C45H70N2O2	1
1	CC50 = 3700 nM	TI LI LO TS
CP0485161 Compound Info	4-[(1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-3a-[(3-hydroxypropylamino)methyl]-5a,5b,8,8,11a-pentamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,11,11b,12,13,13a,13b-tetradecahydrocyclopenta[a]chrysen-9-yl]benzoic acid Show/Hide	C40H59NO3	1
1	CC50 = 4600 nM	TI LI LO TS
CP0489812 Compound Info	4-[(1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-3a-[[2-(dimethylamino)ethylamino]methyl]-5a,5b,8,8,11a-pentamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,11,11b,12,13,13a,13b-tetradecahydrocyclopenta[a]chrysen-9-yl]benzoic acid Show/Hide	C41H62N2O2	1
1	CC50 = 1200 nM	TI LI LO TS
CP0518045 Compound Info	4-[(1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-5a,5b,8,8,11a-pentamethyl-3a-[[2-(4-methylpiperazin-1-yl)ethylamino]methyl]-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,11,11b,12,13,13a,13b-tetradecahydrocyclopenta[a]chrysen-9-yl]benzoic acid Show/Hide	C44H67N3O2	1
1	CC50 = 970 nM	TI LI LO TS
CP0526356 Compound Info	4-[(1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-3a-[[2-(2-hydroxyethylamino)ethylamino]methyl]-5a,5b,8,8,11a-pentamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,11,11b,12,13,13a,13b-tetradecahydrocyclopenta[a]chrysen-9-yl]benzoic acid Show/Hide	C41H62N2O3	1
1	CC50 = 2000 nM	TI LI LO TS
CP0553548 Compound Info	2-chloro-N-[6-cyano-3-[2-[2-(2,4-dioxopyrimidin-1-yl)ethoxy]phenoxy]-4-methylnaphthalen-1-yl]-N-methylacetamide Show/Hide	C27H23ClN4O5	1
1	CC50 = 32000 nM	TI LI LO TS
CP0566677 Compound Info	4-[(1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-3a-[(3-aminopropylamino)methyl]-5a,5b,8,8,11a-pentamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,11,11b,12,13,13a,13b-tetradecahydrocyclopenta[a]chrysen-9-yl]benzoic acid Show/Hide	C40H60N2O2	1
1	CC50 = 120 nM	TI LI LO TS
CP0697005 Compound Info	(4S)-5-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[3-[[(2S)-6-[[2-[4-[3-[[(3S,4aR,6aR,6bS,8aS,11R,12S,12aS,14aR,14bR)-4,4,6a,6b,11,12,14b-heptamethyl-8a-prop-2-enoxycarbonyl-2,3,4a,5,6,7,8,9,10,11,12,12a,14,14a-tetradecahydro-1H-picen-3-yl]oxy]-3-oxopropyl]triazol-1-yl]acetyl]amino]-1-amino-1-oxohexan-2-yl]amino]-3-oxopropyl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]amino]-5-amino-1,5-dioxopentan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]amino]-4-amino-1,4-dioxobutan-2-yl]amino]-6-amino-1-oxohexan-2-yl]amino]-4-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-4-amino-4-oxobutanoyl]amino]-4-amino-4-oxobutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-hydroxybutanoyl]amino]-3-hydroxypropanoyl]amino]-4-methylpentanoyl]amino]-3-methylpentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-hydroxypropanoyl]amino]-4-methylpentanoyl]amino]-3-methylpentanoyl]amino]-4-carboxybutanoyl]amino]-4-carboxybutanoyl]amino]-3-hydroxypropanoyl]amino]-5-amino-5-oxopentanoyl]amino]-4-amino-4-oxobutanoyl]amino]-5-amino-5-oxopentanoyl]amino]-5-amino-5-oxopentanoyl]amino]-5-oxopentanoic acid Show/Hide	C182H286N44O57	1
1	CC50 = 7.92 nM	TI LI LO TS
CP0808980 Compound Info	(4S)-5-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[3-[[(2S)-6-[[2-[4-[3-[[(1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-5a,5b,8,8,11a-pentamethyl-3a-prop-2-enoxycarbonyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysen-9-yl]oxy]-3-oxopropyl]triazol-1-yl]acetyl]amino]-1-amino-1-oxohexan-2-yl]amino]-3-oxopropyl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]amino]-5-amino-1,5-dioxopentan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]amino]-4-amino-1,4-dioxobutan-2-yl]amino]-6-amino-1-oxohexan-2-yl]amino]-4-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-4-amino-4-oxobutanoyl]amino]-4-amino-4-oxobutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-hydroxybutanoyl]amino]-3-hydroxypropanoyl]amino]-4-methylpentanoyl]amino]-3-methylpentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-hydroxypropanoyl]amino]-4-methylpentanoyl]amino]-3-methylpentanoyl]amino]-4-carboxybutanoyl]amino]-4-carboxybutanoyl]amino]-3-hydroxypropanoyl]amino]-5-amino-5-oxopentanoyl]amino]-4-amino-4-oxobutanoyl]amino]-5-amino-5-oxopentanoyl]amino]-5-amino-5-oxopentanoyl]amino]-5-oxopentanoic acid Show/Hide	C182H286N44O57	1
1	CC50 = 14.3 nM	TI LI LO TS
CP0915391 Compound Info	(4S)-4-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[3-[[2-[4-[[(4aS,6aR,6aS,6bR,8aR,10S,12aR,14bS)-10-hydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carbonyl]oxymethyl]triazol-1-yl]acetyl]amino]propanoylamino]-4-amino-4-oxobutanoyl]amino]-4-amino-4-oxobutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-hydroxybutanoyl]amino]-3-hydroxypropanoyl]amino]-4-methylpentanoyl]amino]-3-methylpentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-hydroxypropanoyl]amino]-4-methylpentanoyl]amino]-3-methylpentanoyl]amino]-4-carboxybutanoyl]amino]-4-carboxybutanoyl]amino]-3-hydroxypropanoyl]amino]-5-amino-5-oxopentanoyl]amino]-4-amino-4-oxobutanoyl]amino]-5-amino-5-oxopentanoyl]amino]-5-amino-5-oxopentanoyl]amino]-5-[[(2S)-6-amino-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-5-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-1-oxohexan-2-yl]amino]-5-oxopentanoic acid Show/Hide	C169H266N42O54	1
1	CC50 > 25 nM	TI LI LO TS
CP0946257 Compound Info	(4S)-4-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S,3R)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[3-[[2-[4-[[(1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-acetyloxy-5a,5b,8,8,11a-pentamethyl-1-prop-1-en-2-yl-1,2,3,4,5,6,7,7a,9,10,11,11b,12,13,13a,13b-hexadecahydrocyclopenta[a]chrysene-3a-carbonyl]oxymethyl]triazol-1-yl]acetyl]amino]propanoylamino]-4-amino-4-oxobutanoyl]amino]-4-amino-4-oxobutanoyl]amino]-3-(4-hydroxyphenyl)propanoyl]amino]-3-hydroxybutanoyl]amino]-3-hydroxypropanoyl]amino]-4-methylpentanoyl]amino]-3-methylpentanoyl]amino]-3-(1H-imidazol-5-yl)propanoyl]amino]-3-hydroxypropanoyl]amino]-4-methylpentanoyl]amino]-3-methylpentanoyl]amino]-4-carboxybutanoyl]amino]-4-carboxybutanoyl]amino]-3-hydroxypropanoyl]amino]-5-amino-5-oxopentanoyl]amino]-4-amino-4-oxobutanoyl]amino]-5-amino-5-oxopentanoyl]amino]-5-amino-5-oxopentanoyl]amino]-5-[[(2S)-6-amino-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-5-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-1-oxohexan-2-yl]amino]-5-oxopentanoic acid Show/Hide	C171H268N42O55	1
1	CC50 > 25 nM	TI LI LO TS
CP0955149 Compound Info	(4aS,6aR,6aS,6bR,8aR,10S,12aR,14bS)-10-[3-[1-[2-[[3-[[(2S)-4-amino-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S,3R)-1-[[(2S)-1-[[(2S)-1-[[(2S,3S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S,3S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-5-amino-1-[[(2S)-4-amino-1-[[(2S)-5-amino-1-[[(2S)-5-amino-1-[[(2S)-1-[[(2S)-6-amino-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-5-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-1-oxohexan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-(1H-imidazol-5-yl)-1-oxopropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-3-oxopropyl]amino]-2-oxoethyl]triazol-4-yl]propanoyloxy]-2,2,6a,6b,9,9,12a-heptamethyl-1,3,4,5,6,6a,7,8,8a,10,11,12,13,14b-tetradecahydropicene-4a-carboxylic acid Show/Hide	C171H268N42O55	1
1	CC50 > 25 nM	TI LI LO TS
CP0963501 Compound Info	(S)-N-(2-amino-1-(4-(hydroxymethyl)thiazol-2-yl)ethyl)-5-(3-fluoro-4-(trifluoromethyl)phenyl)-1H-pyrrole-2-carboxamide Show/Hide	C18H16F4N4O2S	1
1	CC50 = 22100 nM	TI LI LO TS

Protein family and CMB statistics Related to the Cell Line

Cell Lines Derived from the same Tissue Source (Umbilical cord blood)

Cell Line Name		Organism	Disease
iPS-SCU-CD34+ #1	Cell Line Info	Homo sapiens (Human)	-
MT-4	Cell Line Info	Homo sapiens (Human)	-
C8166	Cell Line Info	Homo sapiens (Human)	-

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About MolBiC

Correspondence

Prof. Feng ZHU

Prof. Leo, Lianyi Han