Brief Information of the Compound and Protein
Compound Name
US9199981, F8
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PubChem ID
CID: 71280382
SID: 163493036
Canonical SMILES
Cc1ccc(cc1NC(=O)c1cnc2ccccn12)-c1noc(n1)C1CC2(C1)OCCO2
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Compound Formula C23H21N5O4
Compound Structure
Protein Name
Mast/stem cell growth factor receptor Kit
Protein Classification
Enzyme
>
Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase PDGFR family
Uniprot ID
P10721
Gene Name
KIT
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000138 M-07e Homo sapiens (Human)  1
1
IC50 = 55 nM
   TI
   LI
   LO
   TS