Brief Information of the Compound and Protein
Compound Name
US9199981, F89
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Canonical SMILES
Cc1ccn2c(cnc2c1)C(=O)Nc1cc(ccc1C)-c1noc(n1)[C@H]1C[C@@](O)(C1)C(F)(F)F
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Compound Formula C23H20F3N5O3
Compound Structure
Protein Name
Mast/stem cell growth factor receptor Kit
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
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TK protein kinase group
>
Tyrosine protein kinase PDGFR family
Uniprot ID
P10721
Gene Name
KIT
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000138 M-07e Homo sapiens (Human)  1
1
IC50 = 25 nM
   TI
   LI
   LO
   TS