General Information of the Compound
| Compound ID |
CP0382395
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| Compound Name |
N-[[4-(6,7-dimethoxyquinazolin-4-yl)oxyphenyl]carbamoyl]-2-methylbenzamide
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| Structure |
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| Formula |
C25H22N4O5
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| Molecular Weight |
458.474
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| Canonical SMILES |
COc1cc2ncnc(Oc3ccc(NC(=O)NC(=O)c4ccccc4C)cc3)c2cc1OC
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| InChI |
InChI=1S/C25H22N4O5/c1-15-6-4-5-7-18(15)23(30)29-25(31)28-16-8-10-17(11-9-16)34-24-19-12-21(32-2)22(33-3)13-20(19)26-14-27-24/h4-14H,1-3H3,(H2,28,29,30,31)
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| InChIKey |
PEPJPELNFRAZNQ-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00888, Mast/stem cell growth factor receptor Kit
Protein ID: PT01092, Platelet-derived growth factor receptor alpha