Brief Information of the Compound and Protein
Compound Name
ethyl 4-[3-(2-aminoquinazolin-6-yl)-4-methyl-2-oxopyridin-1-yl]benzoate
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PubChem ID
CID: 24879244
SID: 50134650
Canonical SMILES
CCOC(=O)c1ccc(cc1)-n1ccc(C)c(-c2ccc3nc(N)ncc3c2)c1=O
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Compound Formula C23H20N4O3
Compound Structure
Protein Name
Mast/stem cell growth factor receptor Kit
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase PDGFR family
Uniprot ID
P10721
Gene Name
KIT
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000138 M-07e Homo sapiens (Human)  1
1
IC50 = 68 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 17 nM