| Compound ID |
Compound Name |
Compound Formula |
|
CP0781574
|
(S)-5-(1-((1-Acryloylpyrrolidin-3-yl)oxy)-isoquinolin-3-yl)-2,4-dihydro-3H-1,2,4-triazol-3-one
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|
C18H17N5O3
|
1
|
| 1 |
EC50 = 1.259 nM
|
|
|
|
CP0072538
|
4-amino-8-(5-methyl-1H-indazol-6-yl)cinnoline-3-carboxamide
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|
C17H14N6O
|
2
|
| 1 |
EC50 = 28 nM
|
|
|
| 2 |
IC50 = 4000 nM
|
|
|
|
CP0356200
|
4-amino-8-(1H-indazol-6-yl)cinnoline-3-carboxamide
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|
C16H12N6O
|
2
|
| 1 |
EC50 = 92 nM
|
|
|
| 2 |
IC50 = 12000 nM
|
|
|
|
CP0284384
|
3-(1-propan-2-yloxyisoquinolin-3-yl)-1,4-dihydro-1,2,4-triazol-5-one
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|
C14H14N4O2
|
1
|
| 1 |
EC50 = 100 nM
|
|
|
|
CP0546193
|
3-[1-(propan-2-ylamino)isoquinolin-3-yl]-1,4-dihydro-1,2,4-triazol-5-one
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|
C14H15N5O
|
1
|
| 1 |
EC50 = 158.49 nM
|
|
|
|
CP0573587
|
3-(1-propoxyisoquinolin-3-yl)-1,4-dihydro-1,2,4-triazol-5-one
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|
C14H14N4O2
|
1
|
| 1 |
EC50 = 398.11 nM
|
|
|
|
CP0968712
|
(R)-5-(1-((1-acryloylpyrrolidin-3-yl)oxy)isoquinolin-3-yl)-2,4-dihydro-3H-1,2,4-triazol-3-one
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|
C18H17N5O3
|
1
|
| 1 |
EC50 = 501.19 nM
|
|
|
|
CP0570423
|
3-[1-(ethylamino)isoquinolin-3-yl]-1,4-dihydro-1,2,4-triazol-5-one
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|
C13H13N5O
|
1
|
| 1 |
EC50 = 794.33 nM
|
|
|
|
CP0072541
|
4-amino-8-(4-methylpyridin-3-yl)cinnoline-3-carboxamide
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|
C15H13N5O
|
2
|
| 1 |
EC50 = 28600 nM
|
|
|
| 2 |
IC50 = 100000 nM
|
|
|
|
CP0119698
|
4-amino-8-(1-methylpyrazol-4-yl)cinnoline-3-carboxamide
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|
C13H12N6O
|
2
|
| 1 |
EC50 > 50000 nM
|
|
|
| 2 |
IC50 = 240000 nM
|
|
|
|
CP0204006
|
4-aminocinnoline-3-carboxamide
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|
C9H8N4O
|
1
|
| 1 |
IC50 = 3500 nM
|
|
|
|
CP0133162
|
4-amino-8-(1H-indol-6-yl)cinnoline-3-carboxamide
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|
C17H13N5O
|
1
|
| 1 |
IC50 = 850000 nM
|
|
|
