Brief Information of the Compound and Protein
Compound Name
3-(1-propan-2-yloxyisoquinolin-3-yl)-1,4-dihydro-1,2,4-triazol-5-one
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PubChem ID
CID: 162415034
Canonical SMILES
CC(C)Oc1nc(cc2ccccc12)-c1n[nH]c(=O)[nH]1
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Compound Formula C14H14N4O2
Compound Structure
Protein Name
Tyrosine-protein kinase BTK
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Tec family
Uniprot ID
Q06187
Gene Name
BTK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000174 Raji Homo sapiens (Human)  1
1
EC50 = 100 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 10 nM