Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-amino-8-(5-methyl-1H-indazol-6-yl)cinnoline-3-carboxamide
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 PubChem ID
CID: 71765510
Canonical SMILES
Cc1cc2cn[nH]c2cc1-c1cccc2c(N)c(nnc12)C(N)=O
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Compound Formula C17H14N6O
Compound Structure
Protein Name
 Protein Info 
Tyrosine-protein kinase BTK
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Tec family
Uniprot ID
Q06187
Gene Name
BTK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000174 Raji
 Cell Line Info 
Homo sapiens (Human)  2
1
EC50 = 28 nM
   TI
   LI
   LO
   TS
2
IC50 = 4000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 2 nM