1-[3-(2-methoxyethoxy)-4-phenoxyphenyl]-3-(3-methylphenyl)-1,3,5-triazinane-2,4,6-trione

1-(3-bromo-4-phenoxyphenyl)-3-phenyl-1,3,5-triazinane-2,4,6-trione

1-(3-chlorophenyl)-3-[3-(2-methoxyethoxy)-4-phenoxyphenyl]-1,3,5-triazinane-2,4,6-trione

1-(2-methoxy-4-phenoxyphenyl)-3-phenyl-1,3,5-triazinane-2,4,6-trione

1-[3-(2-methoxyethoxy)-4-phenoxyphenyl]-3-(4-methylphenyl)-1,3,5-triazinane-2,4,6-trione

1-(3-methoxy-4-phenoxyphenyl)-3-phenyl-1,3,5-triazinane-2,4,6-trione

1-(3-methyl-4-phenoxyphenyl)-3-phenyl-1,3,5-triazinane-2,4,6-trione

1-(4-phenoxy-3-propan-2-yloxyphenyl)-3-phenyl-1,3,5-triazinane-2,4,6-trione

1-(3-ethoxy-4-phenoxyphenyl)-3-phenyl-1,3,5-triazinane-2,4,6-trione

1-(4-chlorophenyl)-3-[3-(2-methoxyethoxy)-4-phenoxyphenyl]-1,3,5-triazinane-2,4,6-trione

1-methyl-3-[3-(oxetan-3-ylmethoxy)-4-phenoxyphenyl]-1,3,5-triazinane-2,4,6-trione

1-[3-(oxetan-3-ylmethoxy)-4-phenoxyphenyl]-3-phenyl-1,3,5-triazinane-2,4,6-trione

1-[3-(oxolan-3-yloxy)-4-phenoxyphenyl]-3-phenyl-1,3,5-triazinane-2,4,6-trione

1-(3-methoxyphenyl)-3-(4-phenoxyphenyl)-1,3,5-triazinane-2,4,6-trione

1-(4-phenoxyphenyl)-3-phenyl-1,3,5-triazinane-2,4,6-trione

1-[(4S)-4-[2-amino-5-(1-methylimidazol-4-yl)pyridin-3-yl]oxy-3,3-difluoropyrrolidin-1-yl]-2-[4-(trifluoromethoxy)phenyl]ethanone

N-[(5-fluoro-2-methylsulfonylphenyl)methyl]-3-(1-methylpyrazol-4-yl)-1H-indazol-5-amine

N-[(5-fluoro-2-methylsulfonylphenyl)methyl]-3-(6-piperazin-1-ylpyridin-3-yl)-1H-indazol-5-amine

1-[4-(4-amino-7-propan-2-ylpyrrolo[2,3-d]pyrimidine-5-carbonyl)pyridin-2-yl]-3-(2,4-difluorophenyl)urea

N-[(5-fluoro-2-methylsulfonylphenyl)methyl]-3-pyridin-3-yl-1H-indazol-5-amine

1-propan-2-yl-1-(1H-pyrrolo[2,3-b]pyridin-3-ylmethyl)-3-[4-(trifluoromethoxy)phenyl]urea

N-[4-(4-amino-7-propan-2-ylpyrrolo[2,3-d]pyrimidine-5-carbonyl)pyridin-2-yl]-2-(2,4-difluorophenyl)acetamide

N-[5-[2-amino-7-(1-hydroxy-2-methylpropan-2-yl)pyrrolo[2,3-d]pyrimidine-5-carbonyl]pyridin-3-yl]-2-(4-chlorophenyl)acetamide

PF06273340

N-[5-(4-amino-7-propan-2-ylpyrrolo[2,3-d]pyrimidine-5-carbonyl)pyridin-3-yl]-2-(4-chlorophenyl)acetamide

US8846698, 250

N-(5-tert-butyl-2-pyridin-3-ylpyrazol-3-yl)-2-[4-(6-imidazol-1-ylpyridin-3-yl)triazol-1-yl]acetamide

5-(1-methylimidazol-4-yl)-2-[1-[2-[4-(trifluoromethoxy)phenyl]acetyl]piperidin-4-yl]oxybenzamide

6-(1-methylpyrazol-4-yl)-3-[(3R)-1-[2-[4-(trifluoromethoxy)phenyl]acetyl]pyrrolidin-3-yl]oxypyridine-2-carboxamide

1-[(3R,4R)-3-[2-amino-5-(1-methylimidazol-4-yl)pyridin-3-yl]oxy-4-fluoropyrrolidin-1-yl]-2-[4-(trifluoromethoxy)phenyl]ethanone

US8846698, 253

6-amino-5-[(3S)-4,4-difluoro-1-[2-[4-(trifluoromethoxy)phenyl]acetyl]pyrrolidin-3-yl]oxy-N-methylpyridine-3-carboxamide

5-(1-methylpyrazol-4-yl)-2-[1-[2-[4-(trifluoromethoxy)phenyl]acetyl]piperidin-4-yl]oxybenzamide

N-(5-cyclopropyl-2-phenylpyrazol-3-yl)-2-[4-[4-(4-methylimidazol-1-yl)phenyl]triazol-1-yl]acetamide

5-(1-methylimidazol-4-yl)-2-[1-[2-[4-(trifluoromethoxy)phenyl]acetyl]piperidin-4-yl]oxypyridine-3-carboxamide

6-amino-5-[(3S)-4,4-difluoro-1-[2-[4-(trifluoromethoxy)phenyl]acetyl]pyrrolidin-3-yl]oxy-N-ethylpyridine-3-carboxamide

2-[1-[2-[3-fluoro-4-(trifluoromethoxy)phenyl]acetyl]piperidin-4-yl]oxy-5-(1-methylimidazol-4-yl)benzamide

5-(1-methylimidazol-4-yl)-2-[1-[(2S)-2-[4-(trifluoromethoxy)phenyl]propanoyl]piperidin-4-yl]oxybenzamide

US8846698, 69

N-[2-ethyl-5-[7-[(2R)-1-hydroxypropan-2-yl]-6,7-dihydro-5H-cyclopenta[d]pyrimidine-5-carbonyl]pyridin-3-yl]-2-[4-(trifluoromethyl)phenyl]acetamide

US9163021, 21

N-[(2-methylsulfonylphenyl)methyl]-3-(6-piperazin-1-ylpyridin-3-yl)-1H-indazol-5-amine

US9163021, 26

N-[(5-fluoro-2-methylsulfonylphenyl)methyl]-3-pyridin-2-yl-1H-indazol-5-amine

US8846698, 90

6-(1-methylpyrazol-4-yl)-3-[1-[2-[4-(trifluoromethoxy)phenyl]acetyl]piperidin-4-yl]oxypyridine-2-carboxamide

4-[2-carbamoyl-4-(1-methylpyrazol-4-yl)phenoxy]-N-[4-(trifluoromethoxy)phenyl]piperidine-1-carboxamide

N-[2-[[[3-(6-piperazin-1-ylpyridin-3-yl)-1H-indazol-5-yl]amino]methyl]phenyl]methanesulfonamide

5-(1H-pyrazol-5-yl)-1-[2-[4-(trifluoromethoxy)phenoxy]ethyl]indole-2-carboxylic acid

US9163021, 90

N-[2-[[[3-(6-methoxypyridin-3-yl)-1H-indazol-5-yl]amino]methyl]phenyl]methanesulfonamide

2-[1-[2-(4-cyclopropyloxy-3-fluorophenyl)acetyl]piperidin-4-yl]oxy-5-(1-methylimidazol-4-yl)benzamide

N-(5-cyclopropyl-2-phenylpyrazol-3-yl)-2-[4-[3-methoxy-4-(4-methylimidazol-1-yl)phenyl]triazol-1-yl]acetamide

1-(3,5-dichlorophenyl)-3-[2-methoxy-5-(7-propan-2-yl-6,7-dihydro-5H-cyclopenta[d]pyrimidine-5-carbonyl)pyridin-3-yl]urea

N-[2-[[[3-(5-methoxypyridin-3-yl)-1H-indazol-5-yl]amino]methyl]phenyl]methanesulfonamide

1-propan-2-yl-1-[[3-(1,3-thiazol-2-yl)phenyl]methyl]-3-[4-(trifluoromethoxy)phenyl]urea

4-(3-ethoxyphenyl)-1-[2-[4-(trifluoromethoxy)phenoxy]ethyl]pyrrolo[3,2-c]pyridine-2-carboxylic acid

US8846698, 71

N-[2-[[[3-(6-methoxypyridin-2-yl)-1H-indazol-5-yl]amino]methyl]phenyl]methanesulfonamide

N-(1H-benzimidazol-2-ylmethyl)-2-(2-thiophen-2-ylindol-1-yl)acetamide

N-benzyl-3-(6-piperazin-1-ylpyridin-3-yl)-1H-indazol-5-amine

N-[5-(4-amino-7-propan-2-ylpyrrolo[2,3-d]pyrimidine-5-carbonyl)pyridin-3-yl]-2-(4-cyanophenyl)acetamide

N-[(5-fluoro-2-methylsulfonylphenyl)methyl]-3-(1-methylpyrazol-3-yl)-1H-indazol-5-amine

4-(3-ethoxyphenyl)-1-(2-phenoxyethyl)pyrrolo[3,2-c]pyridine-2-carboxylic acid

N-(1H-benzimidazol-2-ylmethyl)-2-[5-fluoro-2-(1,3-oxazol-2-yl)indol-1-yl]acetamide

5-phenylmethoxy-3-(6-piperazin-1-ylpyridin-3-yl)-1H-indazole

5-cyano-1-[2-[4-(trifluoromethoxy)phenoxy]ethyl]indole-2-carboxylic acid

N-[2-[[[3-(6-piperidin-4-yloxypyridin-3-yl)-1H-indazol-5-yl]amino]methyl]phenyl]methanesulfonamide

1-[2-(4-chlorophenoxy)ethyl]-4-(3-ethoxyphenyl)pyrrolo[3,2-c]pyridine-2-carboxylic acid

N-[(5-phenyl-1H-imidazol-2-yl)methyl]-2-(2-thiophen-2-ylindol-1-yl)acetamide

N-(1H-benzimidazol-2-ylmethyl)-2-[2-(1,3-oxazol-2-yl)indol-1-yl]acetamide

N-(imidazo[1,2-a]pyridin-2-ylmethyl)-2-(2-thiophen-2-ylindol-1-yl)acetamide

N-[2-[[[3-[6-(piperidin-4-ylamino)pyridin-3-yl]-1H-indazol-5-yl]amino]methyl]phenyl]methanesulfonamide

N-(2-phenylpropan-2-yl)-3-(6-piperazin-1-ylpyridin-3-yl)-1H-indazol-5-amine

N-benzyl-N-methyl-3-(6-piperazin-1-ylpyridin-3-yl)-1H-indazol-5-amine

1-cyclopropyl-1-[[3-(1,3-thiazol-2-yl)phenyl]methyl]-3-[4-(trifluoromethoxy)phenyl]urea

N-(pyridin-2-ylmethyl)-2-(2-thiophen-2-ylindol-1-yl)acetamide

2-[2-(5-methylthiophen-2-yl)indol-1-yl]-N-(pyridin-2-ylmethyl)acetamide

5-(1-methylimidazol-4-yl)-2-[1-[(2R)-2-[4-(trifluoromethoxy)phenyl]propanoyl]piperidin-4-yl]oxybenzamide

2-(5-fluoro-2-phenylindol-1-yl)-N-(pyridin-2-ylmethyl)acetamide

2-(4-fluoro-2-phenylindol-1-yl)-N-(pyridin-2-ylmethyl)acetamide

N-(pyridin-2-ylmethyl)-2-[2-(1,2-thiazol-3-yl)indol-1-yl]acetamide

1-[(3S,4S)-3-[2-amino-5-(1-methylimidazol-4-yl)pyridin-3-yl]oxy-4-fluoropyrrolidin-1-yl]-2-[4-(trifluoromethoxy)phenyl]ethanone

N-(1H-imidazol-2-ylmethyl)-2-(2-thiophen-2-ylindol-1-yl)acetamide

2-(2-phenylindol-1-yl)-N-(pyridin-2-ylmethyl)acetamide

1-[(4R)-4-[2-amino-5-(1-methylimidazol-4-yl)pyridin-3-yl]oxy-3,3-difluoropyrrolidin-1-yl]-2-[4-(trifluoromethoxy)phenyl]ethanone

2-[(3R,4S)-3-fluoro-1-[2-[4-(trifluoromethoxy)phenyl]acetyl]piperidin-4-yl]oxy-5-(1-methylimidazol-4-yl)pyridine-3-carboxamide

2-[2-(1,3-oxazol-2-yl)indol-1-yl]-N-(pyridin-2-ylmethyl)acetamide

6-(1-methylpyrazol-4-yl)-3-[(3S)-1-[2-[4-(trifluoromethoxy)phenyl]acetyl]pyrrolidin-3-yl]oxypyridine-2-carboxamide

N-(pyridin-2-ylmethyl)-2-[2-(1,3-thiazol-2-yl)indol-1-yl]acetamide

2-(6-fluoro-2-phenylindol-1-yl)-N-(pyridin-2-ylmethyl)acetamide

2-[3,3-difluoro-1-[2-[4-(trifluoromethoxy)phenyl]acetyl]piperidin-4-yl]oxy-5-(1-methylimidazol-4-yl)benzamide

2-[(3S,4R)-3-fluoro-1-[2-[4-(trifluoromethoxy)phenyl]acetyl]piperidin-4-yl]oxy-5-(1-methylimidazol-4-yl)pyridine-3-carboxamide

N-(1,3-thiazol-2-ylmethyl)-2-(2-thiophen-2-ylindol-1-yl)acetamide

N-[(2-phenyl-1H-imidazol-5-yl)methyl]-2-(2-thiophen-2-ylindol-1-yl)acetamide

N-(pyridin-2-ylmethyl)-2-[2-(1,2-thiazol-5-yl)indol-1-yl]acetamide

N-(pyridin-4-ylmethyl)-2-(2-thiophen-2-ylindol-1-yl)acetamide

2-[(3S,4S)-3-fluoro-1-[2-[4-(trifluoromethoxy)phenyl]acetyl]piperidin-4-yl]oxy-5-(1-methylimidazol-4-yl)pyridine-3-carboxamide

N-(1,3-oxazol-2-ylmethyl)-2-(2-thiophen-2-ylindol-1-yl)acetamide

2-[(3R,4S)-3-fluoro-1-[2-[4-(trifluoromethoxy)phenyl]acetyl]piperidin-4-yl]oxy-4-(2-hydroxy-2-methylpropoxy)benzamide

N-(pyrimidin-2-ylmethyl)-2-(2-thiophen-2-ylindol-1-yl)acetamide

N-(pyridin-3-ylmethyl)-2-(2-thiophen-2-ylindol-1-yl)acetamide

N-(1H-imidazol-5-ylmethyl)-2-(2-thiophen-2-ylindol-1-yl)acetamide

2-(2-pyridin-2-ylindol-1-yl)-N-(pyridin-2-ylmethyl)acetamide

2-[2-(5-methylfuran-2-yl)indol-1-yl]-N-(pyridin-2-ylmethyl)acetamide

2-[(3S,4R)-3-fluoro-1-[2-[4-(trifluoromethoxy)phenyl]acetyl]piperidin-4-yl]oxy-4-(2-hydroxy-2-methylpropoxy)benzamide

2-(2-phenylpyrrolo[2,3-c]pyridin-1-yl)-N-(pyridin-2-ylmethyl)acetamide

1-[2-[4-(trifluoromethoxy)phenoxy]ethyl]pyrrolo[3,2-c]pyridine-2-carboxylic acid

2-(2-phenylpyrrolo[3,2-c]pyridin-1-yl)-N-(pyridin-2-ylmethyl)acetamide

2-(7-fluoro-2-phenylindol-1-yl)-N-(pyridin-2-ylmethyl)acetamide

2-[(3S,4R)-3-fluoro-1-[2-[4-(trifluoromethoxy)phenyl]acetyl]piperidin-4-yl]oxy-4-(1-hydroxy-2-methylpropan-2-yl)oxybenzamide

2-(2-pyridin-4-ylindol-1-yl)-N-(pyridin-2-ylmethyl)acetamide

N-(pyrazin-2-ylmethyl)-2-(2-thiophen-2-ylindol-1-yl)acetamide

N-methyl-N-(pyridin-2-ylmethyl)-2-(2-thiophen-2-ylindol-1-yl)acetamide

N-(pyridin-2-ylmethyl)-2-[2-(1,3-thiazol-5-yl)indol-1-yl]acetamide

2-[(3S,4S)-3-fluoro-1-[2-[4-(trifluoromethoxy)phenyl]acetyl]piperidin-4-yl]oxy-4-(2-hydroxy-2-methylpropoxy)benzamide

N-(pyridin-2-ylmethyl)-2-thiophen-2-ylindole-1-carboxamide

2-[(3R,4R)-3-fluoro-1-[2-[4-(trifluoromethoxy)phenyl]acetyl]piperidin-4-yl]oxy-5-(1-methylimidazol-4-yl)pyridine-3-carboxamide

N-[2-(2-thiophen-2-ylindol-1-yl)ethyl]pyridine-2-carboxamide

2-(2-phenylpyrrolo[3,2-b]pyridin-1-yl)-N-(pyridin-2-ylmethyl)acetamide

N-[2-(2-thiophen-2-ylindol-1-yl)ethyl]pyridine-2-sulfonamide

N-[(1-methylimidazol-2-yl)methyl]-2-(2-thiophen-2-ylindol-1-yl)acetamide

2-(2-pyridin-3-ylindol-1-yl)-N-(pyridin-2-ylmethyl)acetamide

N-(pyridin-2-ylmethyl)-2-(2-thiophen-2-ylindol-1-yl)ethanamine

N-pyridin-2-yl-2-(2-thiophen-2-ylindol-1-yl)acetamide

N-(2-pyridin-2-ylethyl)-2-thiophen-2-ylindole-1-carboxamide

2-(2-phenylpyrrolo[2,3-b]pyridin-1-yl)-N-(pyridin-2-ylmethyl)acetamide

5-(2-phenylethyl)-3-(6-piperazin-1-ylpyridin-3-yl)-1H-indazole

N-benzyl-2-(2-thiophen-2-ylindol-1-yl)acetamide