General Information of the Compound
| Compound ID |
CP0457115
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| Compound Name |
N-(pyrimidin-2-ylmethyl)-2-(2-thiophen-2-ylindol-1-yl)acetamide
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| Structure |
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| Formula |
C19H16N4OS
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| Molecular Weight |
348.431
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| Canonical SMILES |
O=C(Cn1c(cc2ccccc12)-c1cccs1)NCc1ncccn1
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| InChI |
InChI=1S/C19H16N4OS/c24-19(22-12-18-20-8-4-9-21-18)13-23-15-6-2-1-5-14(15)11-16(23)17-7-3-10-25-17/h1-11H,12-13H2,(H,22,24)
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| InChIKey |
PKAMBYZNJPJUFT-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00934, High affinity nerve growth factor receptor
Protein ID: PT00936, NT-3 growth factor receptor