Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-cyclopropyl-1-[[3-(1,3-thiazol-2-yl)phenyl]methyl]-3-[4-(trifluoromethoxy)phenyl]urea
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 PubChem ID
CID: 74627728
Canonical SMILES
FC(F)(F)Oc1ccc(NC(=O)N(Cc2cccc(c2)-c2nccs2)C2CC2)cc1
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Compound Formula C21H18F3N3O2S
Compound Structure
Protein Name
 Protein Info 
High affinity nerve growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Trk family
Uniprot ID
P04629
Gene Name
NTRK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000043 U2OS
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 549 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 4233 nM
2 Kd = 400 nM