Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-(5-tert-butyl-2-pyridin-3-ylpyrazol-3-yl)-2-[4-(6-imidazol-1-ylpyridin-3-yl)triazol-1-yl]acetamide
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 PubChem ID
CID: 90645511
Canonical SMILES
CC(C)(C)c1cc(NC(=O)Cn2cc(nn2)-c2ccc(nc2)-n2ccnc2)n(n1)-c1cccnc1
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Compound Formula C24H24N10O
Compound Structure
Protein Name
 Protein Info 
High affinity nerve growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Trk family
Uniprot ID
P04629
Gene Name
NTRK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000043 U2OS
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 7 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 9 nM
2 Kd = 0.94 nM