Brief Information of the Compound and Protein
Compound Name
1-(3,5-dichlorophenyl)-3-[2-methoxy-5-(7-propan-2-yl-6,7-dihydro-5H-cyclopenta[d]pyrimidine-5-carbonyl)pyridin-3-yl]urea
    Show/Hide
PubChem ID
CID: 134148467
Canonical SMILES
COc1ncc(cc1NC(=O)Nc1cc(Cl)cc(Cl)c1)C(=O)C1CC(C(C)C)c2ncncc12
    Show/Hide
Compound Formula C24H23Cl2N5O3
Compound Structure
Protein Name
High affinity nerve growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Trk family
Uniprot ID
P04629
Gene Name
NTRK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000043 U2OS Homo sapiens (Human)  1
1
IC50 = 48 nM
   TI
   LI
   LO
   TS