Brief Information of the Compound and Protein
Compound Name
2-[3,3-difluoro-1-[2-[4-(trifluoromethoxy)phenyl]acetyl]piperidin-4-yl]oxy-5-(1-methylimidazol-4-yl)benzamide
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PubChem ID
CID: 132014694
Canonical SMILES
Cn1cnc(c1)-c1ccc(OC2CCN(CC2(F)F)C(=O)Cc2ccc(OC(F)(F)F)cc2)c(c1)C(N)=O
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Compound Formula C25H23F5N4O4
Compound Structure
Protein Name
High affinity nerve growth factor receptor
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase Trk family
Uniprot ID
P04629
Gene Name
NTRK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000043 U2OS Homo sapiens (Human)  1
1
IC50 = 2800 nM
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