Brief Information of the Compound and Protein
Compound Name
 Compound Info 
US8846698, 250
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 PubChem ID
CID: 90683761
Canonical SMILES
CC(C)n1cc(C(=O)c2cncc(NC(=O)Cc3ccc(Cl)cc3)c2)c2cnc(N)nc12
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Compound Formula C23H21ClN6O2
Compound Structure
Protein Name
 Protein Info 
High affinity nerve growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Trk family
Uniprot ID
P04629
Gene Name
NTRK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000043 U2OS
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 6 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 3.48 nM