Brief Information of the Compound and Protein
Compound Name
N-[2-ethyl-5-[7-[(2R)-1-hydroxypropan-2-yl]-6,7-dihydro-5H-cyclopenta[d]pyrimidine-5-carbonyl]pyridin-3-yl]-2-[4-(trifluoromethyl)phenyl]acetamide
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PubChem ID
CID: 134155803
Canonical SMILES
CCc1ncc(cc1NC(=O)Cc1ccc(cc1)C(F)(F)F)C(=O)C1CC([C@@H](C)CO)c2ncncc12
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Compound Formula C27H27F3N4O3
Compound Structure
Protein Name
High affinity nerve growth factor receptor
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TK protein kinase group
>
Tyrosine protein kinase Trk family
Uniprot ID
P04629
Gene Name
NTRK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000043 U2OS Homo sapiens (Human)  1
1
IC50 = 13 nM
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