Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-[(3S,4S)-3-fluoro-1-[2-[4-(trifluoromethoxy)phenyl]acetyl]piperidin-4-yl]oxy-5-(1-methylimidazol-4-yl)pyridine-3-carboxamide
    Show/Hide
 PubChem ID
CID: 118167694
Canonical SMILES
Cn1cnc(c1)-c1cnc(O[C@H]2CCN(C[C@@H]2F)C(=O)Cc2ccc(OC(F)(F)F)cc2)c(c1)C(N)=O
    Show/Hide
Compound Formula C24H23F4N5O4
Compound Structure
Protein Name
 Protein Info 
High affinity nerve growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Trk family
Uniprot ID
P04629
Gene Name
NTRK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000043 U2OS
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 5400 nM
   TI
   LI
   LO
   TS