General Information of the Protein
Protein ID
PT06617
Protein Name
Taste receptor type 2 member 60
Secondarily
Protein Name
Taste receptor type 2 member 56
Gene Name
TAS2R60
Sequence
MNGDHMVLGSSVTDKKAIILVTILLLLRLVAIAGNGFITAALGVEWVLRRMLLPCDKLLVSLGASRFCLQSVVMGKTIYVFLHPMAFPYNPVLQFLAFQWDFLNAATLWSSTWLSVFYCVKIATFTHPVFFWLKHKLSGWLPWMLFSSVGLSSFTTILFFIGNHRMYQNYLRNHLQPWNVTGDSIRSYCEKFYLFPLKMITWTMPTAVFFICMILLITSLGRHRKKALLTTSGFREPSVQAHIKALLALLSFAMLFISYFLSLVFSAAGIFPPLDFKFWVWESVIYLCAAVHPIILLFSNCRLRAVLKSRRSSRCGTP
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Organism
Homo sapiens, Human
Protein Classification
Membrane receptor
>
Taste family G protein-coupled receptor
>
Taste receptor (taste family GPCR)
Function
Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity).
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Uniprot ID
Primary ID:
P59551

Secondarily ID:
A4D2G8
Q645W8
Q7RTR7
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Ensembl ID
ENSG00000185899
HGNC ID
HGNC:20639
Subcellular Location
Membrane
Map of Molecular Bioactivity Related to the Protein
Map of Molecular Bioactivity Related to the Protein

Protein
Cell Line
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Protein
Cell Line ID: CL000043 , U2OS
Compound ID Compound Name Compound Formula
CP0006743
4-methoxy-N-(2,4,6-trimethylphenyl)benzenesulfonamide
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C16H19NO3S
 1
1
EC50 > 50118.72 nM
   TI
   LI
   LO
   TS