| Compound ID |
Compound Name |
Compound Formula |
|
CP0542662
|
4-[3-[2-(6-chloropyridin-2-yl)oxyethyl]-2-methylimidazo[4,5-b]pyridin-5-yl]pyridine-2,6-diamine
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|
C19H18ClN7O
|
1
|
| 1 |
IC50 = 26 nM
|
|
|
|
CP0546345
|
4-[2-methyl-3-(2,2,2-trifluoroethyl)imidazo[4,5-b]pyridin-5-yl]pyridine-2,6-diamine
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|
C14H13F3N6
|
1
|
| 1 |
IC50 = 28 nM
|
|
|
|
CP0546346
|
4-[3-[2-(6-bromopyridin-2-yl)oxyethyl]-2-methylimidazo[4,5-b]pyridin-5-yl]pyridine-2,6-diamine
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|
C19H18BrN7O
|
1
|
| 1 |
IC50 = 32 nM
|
|
|
|
CP0573622
|
4-[3-(2,2-difluoroethyl)-2-methylimidazo[4,5-b]pyridin-5-yl]pyridine-2,6-diamine
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|
C14H14F2N6
|
1
|
| 1 |
IC50 = 34 nM
|
|
|
|
CP0542659
|
4-[2-methyl-3-(2-phenoxyethyl)imidazo[4,5-b]pyridin-5-yl]pyridine-2,6-diamine
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|
C20H20N6O
|
1
|
| 1 |
IC50 = 35 nM
|
|
|
|
CP0567799
|
4-[3-[(2R)-2-(6-bromopyridin-2-yl)oxypropyl]-2-methylimidazo[4,5-b]pyridin-5-yl]pyridine-2,6-diamine
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|
C20H20BrN7O
|
1
|
| 1 |
IC50 = 44 nM
|
|
|
|
CP0572103
|
4-[2-methyl-3-(4,4,4-trifluorobutyl)imidazo[4,5-b]pyridin-5-yl]pyridine-2,6-diamine
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|
C16H17F3N6
|
1
|
| 1 |
IC50 = 47 nM
|
|
|
|
CP0571356
|
4-[2-methyl-3-[(2S)-2-phenoxypropyl]imidazo[4,5-b]pyridin-5-yl]pyridine-2,6-diamine
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|
C21H22N6O
|
1
|
| 1 |
IC50 = 73 nM
|
|
|
|
CP0578032
|
4-(3-cyclopentyl-2-methylimidazo[4,5-b]pyridin-5-yl)pyridine-2,6-diamine
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|
C17H20N6
|
1
|
| 1 |
IC50 = 80 nM
|
|
|
|
CP0579328
|
4-[2-methyl-3-(2-pyridin-2-yloxyethyl)imidazo[4,5-b]pyridin-5-yl]pyridine-2,6-diamine
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|
C19H19N7O
|
1
|
| 1 |
IC50 = 89 nM
|
|
|
|
CP0175586
|
4-(3-cyclopropyl-2-methylimidazo[4,5-b]pyridin-5-yl)pyridine-2,6-diamine
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|
C15H16N6
|
1
|
| 1 |
IC50 = 90 nM
|
|
|
|
CP0546343
|
4-(3-butyl-2-methylimidazo[4,5-b]pyridin-5-yl)pyridine-2,6-diamine
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|
C16H20N6
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0546344
|
4-[3-(2-cyclohexylethyl)-2-methylimidazo[4,5-b]pyridin-5-yl]pyridine-2,6-diamine
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|
C20H26N6
|
1
|
| 1 |
IC50 = 110 nM
|
|
|
|
CP0344179
|
4-[2-methyl-3-[(2R)-2-phenoxypropyl]imidazo[4,5-b]pyridin-5-yl]pyridine-2,6-diamine
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|
C21H22N6O
|
1
|
| 1 |
IC50 = 111 nM
|
|
|
|
CP0574230
|
4-(2,3-dibutylimidazo[4,5-b]pyridin-5-yl)pyridine-2,6-diamine
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|
C19H26N6
|
1
|
| 1 |
IC50 = 128 nM
|
|
|
|
CP0542660
|
4-[2-methyl-3-[(2R)-2-pyridin-2-yloxypropyl]imidazo[4,5-b]pyridin-5-yl]pyridine-2,6-diamine
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|
C20H21N7O
|
1
|
| 1 |
IC50 = 131 nM
|
|
|
|
CP0567798
|
4-(3-butyl-2-ethylimidazo[4,5-b]pyridin-5-yl)pyridine-2,6-diamine
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|
C17H22N6
|
1
|
| 1 |
IC50 = 153 nM
|
|
|
|
CP0574231
|
4-[3-[2-(furan-2-yl)ethyl]-2-methylimidazo[4,5-b]pyridin-5-yl]pyridine-2,6-diamine
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|
C18H18N6O
|
1
|
| 1 |
IC50 = 226 nM
|
|
|
|
CP0573621
|
4-(3-tert-butyl-2-methylimidazo[4,5-b]pyridin-5-yl)pyridine-2,6-diamine
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|
C16H20N6
|
1
|
| 1 |
IC50 = 228 nM
|
|
|
|
CP0576679
|
4-(2,3-dimethylimidazo[4,5-b]pyridin-5-yl)pyridine-2,6-diamine
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|
C13H14N6
|
1
|
| 1 |
IC50 = 250 nM
|
|
|
|
CP0569842
|
4-[3-(3-methoxypropyl)-2-methylimidazo[4,5-b]pyridin-5-yl]pyridine-2,6-diamine
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|
C16H20N6O
|
1
|
| 1 |
IC50 = 280 nM
|
|
|
|
CP0573620
|
4-(1-benzofuran-5-yl)pyridine-2,6-diamine
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|
C13H11N3O
|
1
|
| 1 |
IC50 = 500 nM
|
|
|
|
CP0574232
|
4-(2,3-dimethyl-1-benzofuran-5-yl)pyridine-2,6-diamine
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|
C15H15N3O
|
1
|
| 1 |
IC50 = 1650 nM
|
|
|
|
CP0576298
|
4-(2-methyl-1-benzofuran-5-yl)pyridine-2,6-diamine
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|
C14H13N3O
|
1
|
| 1 |
IC50 = 1800 nM
|
|
|
|
CP0542658
|
4-[3-[(4-fluorophenyl)methyl]-2-methylimidazo[4,5-b]pyridin-5-yl]pyridine-2,6-diamine
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|
C19H17FN6
|
1
|
| 1 |
IC50 = 3000 nM
|
|
|
|
CP0579329
|
4-[2-methyl-3-[(2S)-2-pyridin-2-yloxypropyl]imidazo[4,5-b]pyridin-5-yl]pyridine-2,6-diamine
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|
C20H21N7O
|
1
|
| 1 |
IC50 > 300 nM
|
|
|
